DepMap
The Cancer Dependency Map (DepMap) is a genome-wide pooled CRISPR-Cas9 knockout and small molecule screen of cancer cell lines. The goal of DepMap is to systematically identify cancer dependencies and the biomarkers that predict them. DepMap provides open access to key cancer dependencies, analytical tools, and visualization resources for the research community.
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"doi": "10.1038/ng.3984", "id": "doi:10.1038/ng.3984", "journal": "Nature Genetics", "title": "Computational correction of copy number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells", "year": "2017"}, {"authors": ["Tsherniak A", "Vazquez F", "Montgomery PG", "Weir BA", "Kryukov G", "Cowley GS"], "doi": "10.1016/j.cell.2017.06.010", "id": "doi:10.1016/j.cell.2017.06.010", "journal": "Cell", "title": "Defining a Cancer Dependency Map", "year": "2017"}], "repository": "https://github.com/broadinstitute/depmap_omics", "taxon": ["NCBITaxon:9606"]}