Probe Miner
Probe Miner is a public resource for the objective, quantitative, and data-driven assessment of chemical probes for protein targets, developed at the Institute of Cancer Research. It integrates large-scale, publicly available medicinal chemistry and bioactivity data to score small molecules against six objective criteria, enabling researchers to evaluate the suitability of compounds as chemical probes for a given protein target. The resource helps reduce the misuse of poor-quality chemical probes in target validation and chemical biology by surfacing potency, selectivity, and cell-based activity evidence in a transparent, reproducible way.
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