Connectivity Map
The Connectivity Map (CMap) is a collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules and simple pattern-matching algorithms that together enable the discovery of functional connections between drugs, genes, and diseases through common gene-expression changes. The original CMap resource is now integrated into the CLUE platform.
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Crawford", "David Peck", "Joshua W. Modell", "Irene C. Blat", "Matthew J. Wrobel", "Jim Lerner", "Jean-Philippe Brunet", "Aravind Subramanian", "Kenneth N. Ross", "Michael Reich", "Haley Hieronymus", "Guo Wei", "Scott A. Armstrong", "Stephen J. Haggarty", "Paul A. Clemons", "Ru Wei", "Steven A. Carr", "Eric S. Lander", "Todd R. Golub"], "doi": "10.1126/science.1132939", "id": "https://doi.org/10.1126/science.1132939", "journal": "Science", "title": "The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease", "year": "2006"}], "repository": "https://clue.io/about", "taxon": ["NCBITaxon:9606"]}