CollecTRI
CollecTRI is a comprehensive collection of signed transcription factor (TF)-target gene regulatory interactions compiled from 12 different resources. It provides high-confidence regulons with expanded TF coverage and the sign (activation or repression) of each interaction, enabling accurate estimation of transcription factor activities from gene expression data. The regulons are distributed through the decoupler ecosystem and OmniPath for downstream enrichment and footprint analysis.
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