HomoloGene
HomoloGene was NCBI's database of homologs (genes with common ancestry) from completely sequenced eukaryotic genomes. The database organized genes into homology groups representing putative orthologs and paralogs across multiple species. HomoloGene was retired in January 2024 and replaced by the NCBI Orthologs dataset, which is now accessible through NCBI Datasets and the Gene database. The last HomoloGene build (build 68) was produced in 2014 and is no longer aligned with current data in NCBI RefSeq and Gene. Historical data from build 68 remains available on FTP for archival purposes only.
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