Clinical Knowledge Graph (CKG)
The Clinical Knowledge Graph (CKG) is an open-source platform that integrates proteomics and clinical data with knowledge from diverse biomedical databases and literature to support precision medicine. The CKG has reported scale of ~16 million nodes and ~220 million relationships and provides tooling for analysis, reporting, and knowledge discovery.
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{"activity_status": "active", "category": "KnowledgeGraph", "contacts": [{"category": "Organization", "contact_details": [{"contact_type": "url", "value": "https://github.com/MannLabs"}], "label": "Mann Labs"}], "description": "The Clinical Knowledge Graph (CKG) is an open-source platform that integrates proteomics and clinical data with knowledge from diverse biomedical databases and literature to support precision medicine. The CKG has reported scale of ~16 million nodes and ~220 million relationships and provides tooling for analysis, reporting, and knowledge discovery.", "domains": ["clinical", "proteomics", "biomedical", "health"], "evaluation_page": "resource/clinicalkg/clinicalkg_eval.html", "homepage_url": "https://ckg.readthedocs.io/", "id": "clinicalkg", "layout": "resource_detail", "license": {"id": "https://opensource.org/licenses/MIT", "label": "MIT License"}, "name": "Clinical Knowledge Graph (CKG)", "products": [{"category": "GraphProduct", "description": "Neo4j database dump of the Clinical Knowledge Graph and additional relationships", "dump_format": "neo4j", "edge_count": 220000000, "format": "mixed", "id": "clinicalkg.graph", "name": "CKG Graph Dump", "node_count": 16000000, "original_source": ["uniprot", "tissues", "string", "stitch", "smpdb", "signor", "sider", "refseq", "reactome", "phosphositeplus", "pfam", "oncokb", "mutationds", "intact", "hpa", "hmdb", "hgnc", "gwascatalog", "foodb", "drugbank", "disgenet", "diseases", "dgidb", "corum", "cancer-genome-interpreter", "doid", "bto", "efo", "go", "hp", "snomedct", "mod", "mi", "ms", "uo"], "product_url": "https://data.mendeley.com/datasets/mrcf7f4tc2/1"}], "publications": [{"authors": ["Alberto Santos", "Ana R. Cola\u00e7o", "Annelaura B. Nielsen", "Matthias Mann"], "doi": "10.1101/2020.05.09.084897", "id": "doi:10.1101/2020.05.09.084897", "journal": "bioRxiv", "title": "Clinical Knowledge Graph Integrates Proteomics Data into Clinical Decision-Making", "year": "2020"}], "repository": "https://github.com/MannLabs/CKG", "taxon": ["NCBITaxon:9606"]}