Pharos
Pharos is the user interface to the Target Central Resource Database (TCRD), providing comprehensive information about protein targets with a focus on the druggable genome. Developed by the NIH Illuminating the Druggable Genome (IDG) program, Pharos classifies targets into four Target Development Levels (TDLs) - Tclin (targets with approved drugs), Tchem (targets with high-quality chemical probes), Tbio (targets with biological data), and Tdark (understudied targets with little functional knowledge). The platform integrates data from over 80 datasets covering protein structure, function, pathways, expression, diseases, drugs, ligands, and publications.
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