Ontology for Biomarkers of Clinical Interest
An OWL-formatted ontology that formally defines biomarkers of clinical interest for diseases, phenotypes, and effects, including the FDA-NIH BEST-aligned biomarker role classifications (diagnostic, prognostic, predictive, monitoring, pharmacodynamic/response, safety, and susceptibility/risk biomarkers). OBCI is developed by the clinical-biomarkers group associated with the GlyGen and OncoMX biomarker data resources, and supplies the "role" / best-classification vocabulary used by downstream biomarker knowledge graphs.
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