Autophagy Ontology
ATGO (Autophagy Ontology) is a hierarchical functional ontology of autophagy processes built through Active Interaction Mapping of genetic interaction data from Saccharomyces cerevisiae. The second-generation ontology contains 220 functions representing autophagy organization including vesicle transport, cell cycle, and stress response pathways.
[{"category": "Individual", "label": "Trey Ideker"}, {"category": "Individual", "label": "Subramaniam Subramani"}]
[{"category": "OntologyProduct", "description": "Second-generation hierarchical ontology of 220 autophagy functions built from 156,364 synthetic-lethal genetic interactions across autophagy-activating conditions in Saccharomyces cerevisiae.", "id": "atgo.ontology", "name": "ATGO Hierarchical Ontology", "original_source": ["atgo"], "product_url": "http://atgo.ucsd.edu/", "warnings": ["File was not able to be retrieved when checked on 2026-01-06_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError(\"HTTPConnection(host='atgo.ucsd.edu', port=80)_ Failed to establish a new connection_ [Errno 111] Connection refused\"))", "File was not able to be retrieved when checked on 2026-01-06_ Timeout connecting to URL", "File was not able to be retrieved when checked on 2025-12-13_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fb70a995de0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-11_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f1820ddb470>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-11_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f20808aa410>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-11_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f8e7e642bd0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-11_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f643ec4e980>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-09_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f27e2fc30a0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-08_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f1b77aa6c50>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-08_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fa6d3a1cca0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-07_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fa0ec285880>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-05_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f3acffafe50>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-04_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f3d84d44ca0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-04_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fd6e7c0c320>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-04_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fe0f79162c0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-11-26_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f435f93f250>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-11-25_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f7a1bb3c350>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-11-25_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fecb4d8bdf0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-11-22_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fa9b784b9a0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))"]}]
{"activity_status": "inactive", "category": "Ontology", "contacts": [{"category": "Individual", "label": "Trey Ideker"}, {"category": "Individual", "label": "Subramaniam Subramani"}], "creation_date": "2025-10-30T00:00:00Z", "description": "ATGO (Autophagy Ontology) is a hierarchical functional ontology of autophagy processes built through Active Interaction Mapping of genetic interaction data from Saccharomyces cerevisiae. The second-generation ontology contains 220 functions representing autophagy organization including vesicle transport, cell cycle, and stress response pathways.", "domains": ["biological systems", "systems biology"], "homepage_url": "http://atgo.ucsd.edu/", "id": "atgo", "infores_id": "atgo", "last_modified_date": "2025-11-22T00:00:00Z", "layout": "resource_detail", "name": "Autophagy Ontology", "products": [{"category": "OntologyProduct", "description": "Second-generation hierarchical ontology of 220 autophagy functions built from 156,364 synthetic-lethal genetic interactions across autophagy-activating conditions in Saccharomyces cerevisiae.", "id": "atgo.ontology", "name": "ATGO Hierarchical Ontology", "original_source": ["atgo"], "product_url": "http://atgo.ucsd.edu/", "warnings": ["File was not able to be retrieved when checked on 2026-01-06_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError(\"HTTPConnection(host='atgo.ucsd.edu', port=80)_ Failed to establish a new connection_ [Errno 111] Connection refused\"))", "File was not able to be retrieved when checked on 2026-01-06_ Timeout connecting to URL", "File was not able to be retrieved when checked on 2025-12-13_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fb70a995de0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-11_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f1820ddb470>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-11_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f20808aa410>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-11_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f8e7e642bd0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-11_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f643ec4e980>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-09_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f27e2fc30a0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-08_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f1b77aa6c50>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-08_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fa6d3a1cca0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-07_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fa0ec285880>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-05_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f3acffafe50>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-04_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f3d84d44ca0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-04_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fd6e7c0c320>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-12-04_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fe0f79162c0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-11-26_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f435f93f250>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-11-25_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7f7a1bb3c350>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-11-25_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fecb4d8bdf0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))", "File was not able to be retrieved when checked on 2025-11-22_ Error connecting to URL_ HTTPConnectionPool(host='atgo.ucsd.edu', port=80)_ Max retries exceeded with url_ / (Caused by NewConnectionError('<urllib3.connection.HTTPConnection object at 0x7fa9b784b9a0>_ Failed to establish a new connection_ [Errno 111] Connection refused'))"]}], "publications": [{"authors": ["Michael H Kramer", "Jean-Claude Farr\u00e9", "Koyel Mitra", "Michael Ku Yu", "Keiichiro Ono", "Barry Demchak", "Katherine Licon", "Mikayla Flagg", "Rama Balakrishnan", "J Michael Cherry", "Trey Ideker", "Subramaniam Subramani"], "doi": "10.1016/j.molcel.2016.12.024", "id": "PMID:28132844", "journal": "Molecular Cell", "title": "Active Interaction Mapping Reveals the Hierarchical Organization of Autophagy", "year": "2017"}], "synonyms": ["ATGO"], "taxon": ["NCBITaxon:4932"]}