ToxCast
ToxCast (US EPA Toxicity Forecaster) is a high-throughput screening program generating bioactivity profiles for thousands of environmental chemicals across diverse in vitro assays to prioritize substances for hazard characterization, integrate exposure and pathway information, and support predictive toxicology.
[]
[{"category": "Product", "description": "The EPA has developed the Adverse Outcome Pathway Database (AOP-DB) to better characterize adverse outcomes of toxicological interest that are relevant to human health and the environment. Since its inception, the AOP-DB has been developed with the aim of integrating AOP molecular target information with other publicly available datasets to facilitate computational analyses of AOP information.", "id": "aop-db.data", "name": "AOP-DB Data", "original_source": ["aop-wiki", "ctd", "toxcast", "disgenet", "ncbigene", "string", "1000genomes", "ensembl", "gwascatalog"], "product_url": "https://catalog.data.gov/dataset/adverse-outcome-pathway-database-aop-db-version-2", "secondary_source": ["aop-db"]}, {"category": "GraphicalInterface", "description": "Landing page describing the ToxCast high-throughput screening program and providing links to data and documentation.", "id": "toxcast.portal", "name": "EPA ToxCast Portal", "product_url": "https://www.epa.gov/chemical-research/toxicity-forecasting"}, {"category": "ProgrammingInterface", "description": "REST API providing programmatic access to ToxCast-related assay, chemical, and bioactivity data via the CompTox Chemicals Dashboard.", "id": "toxcast.api", "name": "CompTox Chemicals Dashboard API (ToxCast)", "product_url": "https://api-ccte.epa.gov/dashboard/"}, {"category": "Product", "description": "Bulk release archives (assay annotations, hit-call data, summary tables) for ToxCast phases.", "id": "toxcast.downloads", "name": "ToxCast Bulk Data Downloads", "product_url": "https://www.epa.gov/chemical-research/toxicity-forecasting#data"}]
{"activity_status": "active", "category": "DataSource", "collection": ["ber"], "creation_date": "2025-09-04T00:00:00Z", "description": "ToxCast (US EPA Toxicity Forecaster) is a high-throughput screening program generating bioactivity profiles for thousands of environmental chemicals across diverse in vitro assays to prioritize substances for hazard characterization, integrate exposure and pathway information, and support predictive toxicology.", "domains": ["toxicology", "environment", "public health", "biomedical"], "id": "toxcast", "last_modified_date": "2025-09-16T00:00:00Z", "layout": "resource_detail", "license": {"id": "https://www.epa.gov/privacy/privacy-and-security-notice", "label": "EPA Data Usage & Privacy Notice (public domain / open government data)"}, "name": "ToxCast", "products": [{"category": "Product", "description": "The EPA has developed the Adverse Outcome Pathway Database (AOP-DB) to better characterize adverse outcomes of toxicological interest that are relevant to human health and the environment. Since its inception, the AOP-DB has been developed with the aim of integrating AOP molecular target information with other publicly available datasets to facilitate computational analyses of AOP information.", "id": "aop-db.data", "name": "AOP-DB Data", "original_source": ["aop-wiki", "ctd", "toxcast", "disgenet", "ncbigene", "string", "1000genomes", "ensembl", "gwascatalog"], "product_url": "https://catalog.data.gov/dataset/adverse-outcome-pathway-database-aop-db-version-2", "secondary_source": ["aop-db"]}, {"category": "GraphicalInterface", "description": "Landing page describing the ToxCast high-throughput screening program and providing links to data and documentation.", "id": "toxcast.portal", "name": "EPA ToxCast Portal", "product_url": "https://www.epa.gov/chemical-research/toxicity-forecasting"}, {"category": "ProgrammingInterface", "description": "REST API providing programmatic access to ToxCast-related assay, chemical, and bioactivity data via the CompTox Chemicals Dashboard.", "id": "toxcast.api", "name": "CompTox Chemicals Dashboard API (ToxCast)", "product_url": "https://api-ccte.epa.gov/dashboard/"}, {"category": "Product", "description": "Bulk release archives (assay annotations, hit-call data, summary tables) for ToxCast phases.", "id": "toxcast.downloads", "name": "ToxCast Bulk Data Downloads", "product_url": "https://www.epa.gov/chemical-research/toxicity-forecasting#data"}]}