ProtCID
The Protein Common Interface Database (ProtCID) provides comprehensive, PDB-wide structural information on protein interactions, identifying and clustering interfaces observed in multiple crystal forms of homologous proteins.
[{"category": "Individual", "contact_details": [{"contact_type": "email", "value": "qifang.xu@fccc.edu"}], "label": "Qifang Xu"}, {"category": "Individual", "label": "Roland L. Dunbrack Jr"}, {"category": "Organization", "label": "Fox Chase Cancer Center"}]
[{"category": "Product", "description": "Database containing protein-protein interfaces, domain-domain interfaces, protein-peptide interfaces, and protein-ligand interactions based on structural data from the PDB.", "id": "protcid.database", "name": "ProtCID Database"}, {"category": "GraphicalInterface", "description": "Web interface for searching and visualizing protein interaction data from ProtCID.", "id": "protcid.site", "name": "ProtCID Web Interface", "product_url": "https://dunbrack2.fccc.edu/ProtCID/Search/search.aspx"}, {"category": "GraphProduct", "description": "The SPOKE knowledge graph containing nodes and edges from multiple biomedical data sources.", "id": "spoke.graph", "name": "SPOKE Graph", "original_source": ["ncbigene", "pubmed", "mesh", "pid", "doid", "diseases", "drugcentral", "go", "gwascatalog", "reactome", "lincs-l1000", "uberon", "wikipathways", "bindingdb", "drugbank", "sider", "bgee", "uniprot", "string", "omim", "chembl", "foodb", "civic", "gdsc", "clinicaltrialsgov", "hpa", "cl", "kegg", "metacyc", "bv-brc", "ncbitaxon", "pathophenodb", "pfam", "interpro", "protcid"], "secondary_source": ["spoke"]}]
{"activity_status": "active", "category": "DataSource", "contacts": [{"category": "Individual", "contact_details": [{"contact_type": "email", "value": "qifang.xu@fccc.edu"}], "label": "Qifang Xu"}, {"category": "Individual", "label": "Roland L. Dunbrack Jr"}, {"category": "Organization", "label": "Fox Chase Cancer Center"}], "creation_date": "2025-05-28T00:00:00Z", "description": "The Protein Common Interface Database (ProtCID) provides comprehensive, PDB-wide structural information on protein interactions, identifying and clustering interfaces observed in multiple crystal forms of homologous proteins.", "domains": ["proteomics", "chemistry and biochemistry", "biological systems"], "homepage_url": "http://dunbrack2.fccc.edu/protcid/", "id": "protcid", "last_modified_date": "2025-10-31T00:00:00Z", "layout": "resource_detail", "license": {"id": "https://dunbrack2.fccc.edu/ProtCID/About.aspx", "label": "Custom"}, "name": "ProtCID", "products": [{"category": "Product", "description": "Database containing protein-protein interfaces, domain-domain interfaces, protein-peptide interfaces, and protein-ligand interactions based on structural data from the PDB.", "id": "protcid.database", "name": "ProtCID Database"}, {"category": "GraphicalInterface", "description": "Web interface for searching and visualizing protein interaction data from ProtCID.", "id": "protcid.site", "name": "ProtCID Web Interface", "product_url": "https://dunbrack2.fccc.edu/ProtCID/Search/search.aspx"}, {"category": "GraphProduct", "description": "The SPOKE knowledge graph containing nodes and edges from multiple biomedical data sources.", "id": "spoke.graph", "name": "SPOKE Graph", "original_source": ["ncbigene", "pubmed", "mesh", "pid", "doid", "diseases", "drugcentral", "go", "gwascatalog", "reactome", "lincs-l1000", "uberon", "wikipathways", "bindingdb", "drugbank", "sider", "bgee", "uniprot", "string", "omim", "chembl", "foodb", "civic", "gdsc", "clinicaltrialsgov", "hpa", "cl", "kegg", "metacyc", "bv-brc", "ncbitaxon", "pathophenodb", "pfam", "interpro", "protcid"], "secondary_source": ["spoke"]}], "publications": [{"authors": ["Qifang Xu", "Roland L. Dunbrack"], "id": "https://doi.org/10.1038/s41467-020-14301-4", "journal": "Nature Communications", "preferred": true, "title": "ProtCID: a data resource for structural information on protein interactions", "year": "2020"}, {"authors": ["Qifang Xu", "Roland L. Dunbrack"], "id": "https://doi.org/10.1093/nar/gkq1059", "journal": "Nucleic Acids Research", "title": "The protein common interface database (ProtCID) - a comprehensive database of interactions of homologous proteins in multiple crystal forms", "year": "2011"}, {"authors": ["Qifang Xu", "Adrian Canutescu", "Zhenyu Wang", "Mu Tian", "Thomas Biesiada", "Roland L. Dunbrack"], "id": "https://doi.org/10.1016/j.jmb.2008.06.002", "journal": "Journal of Molecular Biology", "title": "Statistical Analysis of Interface Similarity in Crystals of Homologous Proteins", "year": "2008"}], "repository": "", "tags": ["core"], "version": "3.0"}