HOCOMOCO
HOCOMOCO (HOmo sapiens COmprehensive MOdel COllection) is a curated database of transcription factor (TF) binding models, primarily position weight matrices (PWMs), for human and mouse. The models are derived from large-scale ChIP-Seq and HT-SELEX experiments and are manually curated, benchmarked, and annotated with quality ratings and recommended score thresholds. HOCOMOCO covers over a thousand human and mouse TFs, including secondary motif subtypes, and is a widely used upstream source for downstream regulatory resources such as DoRothEA.
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