name: GTEx
description: The Genotype-Tissue Expression (GTEx) project provides a comprehensive resource to study tissue-specific gene expression and regulation. Samples were collected from 54 non-diseased tissue sites across nearly 1000 individuals, primarily for molecular assays including WGS, WES, and RNA-Seq.
contacts: [{"category": "Organization", "contact_details": [{"contact_type": "email", "value": "gtex-help@broadinstitute.org"}, {"contact_type": "url", "value": "https://www.gtexportal.org/home/contact"}], "label": "GTEx Consortium"}]
products: [{"category": "GraphicalInterface", "description": "GTEx Portal web interface for exploring tissue-specific gene expression data, eQTLs, and other genomic analyses", "format": "http", "id": "gtex.portal", "name": "GTEx Portal", "original_source": ["gtex"], "product_url": "https://www.gtexportal.org/home/"}, {"category": "Product", "description": "Complete GTEx v8 data including gene expression, transcript expression, exon expression, and junction data across tissues", "format": "tsv", "id": "gtex.bulk-data", "name": "GTEx Bulk Data Downloads", "original_source": ["gtex"], "product_url": "https://www.gtexportal.org/home/downloads/adult-gtex"}, {"category": "Product", "description": "eQTL (expression quantitative trait loci) data linking genetic variants to gene expression across tissues", "format": "tsv", "id": "gtex.eqtl-data", "name": "GTEx eQTL Data", "original_source": ["gtex"], "product_url": "https://www.gtexportal.org/home/downloads/adult-gtex/qtl"}, {"category": "ProgrammingInterface", "description": "GTEx REST API for programmatic access to gene expression and eQTL data", "format": "json", "id": "gtex.api", "name": "GTEx REST API", "original_source": ["gtex"], "product_url": "https://gtexportal.org/rest/"}, {"category": "Product", "description": "Individual-level genotype and phenotype data available through dbGaP", "format": "vcf", "id": "gtex.dbgap-data", "name": "GTEx dbGaP Data", "original_source": ["gtex"], "product_url": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000424"}, {"category": "GraphProduct", "description": "GTEx Automat", "format": "kgx-jsonl", "id": "automat.gtex", "infores_id": "automat-gtex", "name": "gtex_automat", "original_source": ["gtex"], "product_url": "https://stars.renci.org/var/plater/bl-4.2.1/GTEx_Automat/a6448b9092bb81a1/", "secondary_source": ["automat"]}, {"category": "Product", "description": "Network embeddings of the Bioteque graph that represent biological entities and their associations", "id": "bioteque.embeddings", "name": "Bioteque Embeddings", "original_source": ["chebi", "cosmic", "achilles", "depmap", "ccle", "gdsc", "cellosaurus", "clue", "ctd", "pharmacodb", "prism", "drugbank", "lincs", "compartments", "offsides", "sider", "drugcentral", "repohub", "chemicalchecker", "repodb", "disgenet", "opentargets", "creeds", "interpro", "reactome", "tissues", "dorothea", "progeny", "gtex", "hpa", "go", "corum", "huri", "intact", "omnipath", "string", "bto"], "product_url": "https://bioteque.irbbarcelona.org/downloads/embeddings", "secondary_source": ["bioteque"]}, {"category": "GraphProduct", "description": "Turnkey neo4j distributions that deploy fully-indexed, standalone UBKG instances as neo4j graph databases, running in a Docker container. Requires UMLS API key to access.", "dump_format": "neo4j", "id": "ubkg.neo4j", "name": "UBKG Neo4j Docker Distribution", "original_source": ["hgnc", "loinc", "icd10", "snomedct", "uberon", "pato", "cl", "do", "obi", "obib", "edam", "hsapdv", "sbo", "mi", "chebi", "mp", "ordo", "uniprot", "uo", "mondo", "efo", "pgo", "gencode", "reactome", "hra", "hubmap", "sennet", "stellar", "dct", "clinvar", "cmap", "hp", "mp", "msigdb", "wikipathways", "clingen", "string", "4dn", "erccrbp", "erccreg", "faldo", "glycordf", "glycocoo", "gtex", "kidsfirst", "lincs", "motrpac", "mw", "npo", "nposckan", "disgenet", "biomarker", "opentargets"], "product_url": "https://ubkg-downloads.xconsortia.org/", "secondary_source": ["ubkg"]}, {"category": "GraphProduct", "description": "Ontology CSV files that can be imported into a neo4j instance to create a UBKG database. Requires UMLS API key to access.", "format": "csv", "id": "ubkg.csv", "name": "UBKG Ontology CSV Files", "original_source": ["hgnc", "loinc", "icd10", "snomedct", "uberon", "pato", "cl", "do", "obi", "obib", "edam", "hsapdv", "sbo", "mi", "chebi", "mp", "ordo", "uniprot", "uo", "mondo", "efo", "pgo", "gencode", "reactome", "hra", "hubmap", "sennet", "stellar", "dct", "clinvar", "cmap", "hp", "mp", "msigdb", "wikipathways", "clingen", "string", "4dn", "erccrbp", "erccreg", "faldo", "glycordf", "glycocoo", "gtex", "kidsfirst", "lincs", "motrpac", "mw", "npo", "nposckan", "disgenet", "biomarker", "opentargets"], "product_url": "https://ubkg-downloads.xconsortia.org/", "secondary_source": ["ubkg"]}, {"category": "GraphProduct", "description": "Integrated graph knowledge base combining Mendelian randomization causal estimates, pathway, QTL, drug, literature-derived, and ontology-backed relationships (Neo4j backend)", "format": "neo4j", "id": "epigraphdb.graph", "name": "EpiGraphDB Graph Database", "original_source": ["epigraphdb", "kg-monarch", "vectology", "ukbiobank", "prsatlas", "eqtlgen", "mondo", "gtex", "ensembl", "cpic", "opentargets", "efo", "semmeddb", "intact", "string", "reactome", "mrbase"], "product_url": "https://docs.epigraphdb.org/graph-database/", "secondary_source": ["epigraphdb"]}]
raw_data: {"activity_status": "active", "category": "DataSource", "contacts": [{"category": "Organization", "contact_details": [{"contact_type": "email", "value": "gtex-help@broadinstitute.org"}, {"contact_type": "url", "value": "https://www.gtexportal.org/home/contact"}], "label": "GTEx Consortium"}], "description": "The Genotype-Tissue Expression (GTEx) project provides a comprehensive resource to study tissue-specific gene expression and regulation. Samples were collected from 54 non-diseased tissue sites across nearly 1000 individuals, primarily for molecular assays including WGS, WES, and RNA-Seq.", "domains": ["genomics", "biomedical", "anatomy and development"], "homepage_url": "https://www.gtexportal.org/home/", "id": "gtex", "layout": "resource_detail", "name": "GTEx", "products": [{"category": "GraphicalInterface", "description": "GTEx Portal web interface for exploring tissue-specific gene expression data, eQTLs, and other genomic analyses", "format": "http", "id": "gtex.portal", "name": "GTEx Portal", "original_source": ["gtex"], "product_url": "https://www.gtexportal.org/home/"}, {"category": "Product", "description": "Complete GTEx v8 data including gene expression, transcript expression, exon expression, and junction data across tissues", "format": "tsv", "id": "gtex.bulk-data", "name": "GTEx Bulk Data Downloads", "original_source": ["gtex"], "product_url": "https://www.gtexportal.org/home/downloads/adult-gtex"}, {"category": "Product", "description": "eQTL (expression quantitative trait loci) data linking genetic variants to gene expression across tissues", "format": "tsv", "id": "gtex.eqtl-data", "name": "GTEx eQTL Data", "original_source": ["gtex"], "product_url": "https://www.gtexportal.org/home/downloads/adult-gtex/qtl"}, {"category": "ProgrammingInterface", "description": "GTEx REST API for programmatic access to gene expression and eQTL data", "format": "json", "id": "gtex.api", "name": "GTEx REST API", "original_source": ["gtex"], "product_url": "https://gtexportal.org/rest/"}, {"category": "Product", "description": "Individual-level genotype and phenotype data available through dbGaP", "format": "vcf", "id": "gtex.dbgap-data", "name": "GTEx dbGaP Data", "original_source": ["gtex"], "product_url": "https://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000424"}, {"category": "GraphProduct", "description": "GTEx Automat", "format": "kgx-jsonl", "id": "automat.gtex", "infores_id": "automat-gtex", "name": "gtex_automat", "original_source": ["gtex"], "product_url": "https://stars.renci.org/var/plater/bl-4.2.1/GTEx_Automat/a6448b9092bb81a1/", "secondary_source": ["automat"]}, {"category": "Product", "description": "Network embeddings of the Bioteque graph that represent biological entities and their associations", "id": "bioteque.embeddings", "name": "Bioteque Embeddings", "original_source": ["chebi", "cosmic", "achilles", "depmap", "ccle", "gdsc", "cellosaurus", "clue", "ctd", "pharmacodb", "prism", "drugbank", "lincs", "compartments", "offsides", "sider", "drugcentral", "repohub", "chemicalchecker", "repodb", "disgenet", "opentargets", "creeds", "interpro", "reactome", "tissues", "dorothea", "progeny", "gtex", "hpa", "go", "corum", "huri", "intact", "omnipath", "string", "bto"], "product_url": "https://bioteque.irbbarcelona.org/downloads/embeddings", "secondary_source": ["bioteque"]}, {"category": "GraphProduct", "description": "Turnkey neo4j distributions that deploy fully-indexed, standalone UBKG instances as neo4j graph databases, running in a Docker container. Requires UMLS API key to access.", "dump_format": "neo4j", "id": "ubkg.neo4j", "name": "UBKG Neo4j Docker Distribution", "original_source": ["hgnc", "loinc", "icd10", "snomedct", "uberon", "pato", "cl", "do", "obi", "obib", "edam", "hsapdv", "sbo", "mi", "chebi", "mp", "ordo", "uniprot", "uo", "mondo", "efo", "pgo", "gencode", "reactome", "hra", "hubmap", "sennet", "stellar", "dct", "clinvar", "cmap", "hp", "mp", "msigdb", "wikipathways", "clingen", "string", "4dn", "erccrbp", "erccreg", "faldo", "glycordf", "glycocoo", "gtex", "kidsfirst", "lincs", "motrpac", "mw", "npo", "nposckan", "disgenet", "biomarker", "opentargets"], "product_url": "https://ubkg-downloads.xconsortia.org/", "secondary_source": ["ubkg"]}, {"category": "GraphProduct", "description": "Ontology CSV files that can be imported into a neo4j instance to create a UBKG database. Requires UMLS API key to access.", "format": "csv", "id": "ubkg.csv", "name": "UBKG Ontology CSV Files", "original_source": ["hgnc", "loinc", "icd10", "snomedct", "uberon", "pato", "cl", "do", "obi", "obib", "edam", "hsapdv", "sbo", "mi", "chebi", "mp", "ordo", "uniprot", "uo", "mondo", "efo", "pgo", "gencode", "reactome", "hra", "hubmap", "sennet", "stellar", "dct", "clinvar", "cmap", "hp", "mp", "msigdb", "wikipathways", "clingen", "string", "4dn", "erccrbp", "erccreg", "faldo", "glycordf", "glycocoo", "gtex", "kidsfirst", "lincs", "motrpac", "mw", "npo", "nposckan", "disgenet", "biomarker", "opentargets"], "product_url": "https://ubkg-downloads.xconsortia.org/", "secondary_source": ["ubkg"]}, {"category": "GraphProduct", "description": "Integrated graph knowledge base combining Mendelian randomization causal estimates, pathway, QTL, drug, literature-derived, and ontology-backed relationships (Neo4j backend)", "format": "neo4j", "id": "epigraphdb.graph", "name": "EpiGraphDB Graph Database", "original_source": ["epigraphdb", "kg-monarch", "vectology", "ukbiobank", "prsatlas", "eqtlgen", "mondo", "gtex", "ensembl", "cpic", "opentargets", "efo", "semmeddb", "intact", "string", "reactome", "mrbase"], "product_url": "https://docs.epigraphdb.org/graph-database/", "secondary_source": ["epigraphdb"]}], "publications": [{"authors": ["GTEx Consortium"], "doi": "10.1126/science.aaz1776", "id": "doi:10.1126/science.aaz1776", "title": "The GTEx Consortium atlas of genetic regulatory effects across human tissues", "year": "2020"}, {"authors": ["GTEx Consortium"], "doi": "10.1126/science.1262110", "id": "doi:10.1126/science.1262110", "title": "The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans", "year": "2015"}], "repository": "https://github.com/broadinstitute/gtex-pipeline"}