Enrichr-KG
Enrichr-KG is a comprehensive knowledge graph that integrates gene set enrichment analysis libraries from Enrichr, connecting genes to biological terms, pathways, diseases, drugs, and other functional annotations across multiple domains and species to enable multi-layered biological discovery and hypothesis generation.
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{"activity_status": "active", "category": "KnowledgeGraph", "contacts": [{"category": "Organization", "contact_details": [{"contact_type": "email", "value": "avi.maayan@mssm.edu"}, {"contact_type": "url", "value": "https://labs.icahn.mssm.edu/maayanlab/"}], "label": "Ma'ayan Laboratory"}], "creation_date": "2025-09-23T00:00:00Z", "description": "Enrichr-KG is a comprehensive knowledge graph that integrates gene set enrichment analysis libraries from Enrichr, connecting genes to biological terms, pathways, diseases, drugs, and other functional annotations across multiple domains and species to enable multi-layered biological discovery and hypothesis generation.", "domains": ["biomedical", "genomics", "systems biology", "drug discovery", "biological systems"], "evaluation_page": "resource/enrichr-kg/enrichr-kg_eval_automated.html", "homepage_url": "https://maayanlab.cloud/enrichr-kg/", "id": "enrichr-kg", "last_modified_date": "2025-09-23T00:00:00Z", "layout": "resource_detail", "license": {"id": "https://creativecommons.org/licenses/by/4.0/", "label": "CC BY 4.0", "logo": "http://mirrors.creativecommons.org/presskit/buttons/80x15/png/by.png"}, "name": "Enrichr-KG", "products": [{"category": "GraphicalInterface", "description": "Interactive web interface for exploring the Enrichr-KG knowledge graph with single and two-term search capabilities", "format": "http", "id": "enrichr-kg.portal", "name": "Enrichr-KG Explorer", "product_url": "https://maayanlab.cloud/enrichr-kg/"}, {"category": "ProgrammingInterface", "description": "API endpoints for programmatic access to Enrichr-KG graph data and enrichment analysis", "format": "http", "id": "enrichr-kg.api", "name": "Enrichr-KG API", "product_url": "https://maayanlab.cloud/enrichr-kg/api/"}, {"category": "GraphProduct", "description": "Neo4j graph database containing integrated gene set enrichment libraries with genes, terms, pathways, and functional annotations", "dump_format": "neo4j", "format": "neo4j", "id": "enrichr-kg.graph", "name": "Enrichr-KG Neo4j Database"}], "publications": [{"authors": ["Evangelista JE", "Xie Z", "Marino GB", "Nguyen N", "Clarke DJB", "Ma'ayan A"], "id": "doi:10.1093/nar/gkad393", "journal": "Nucleic Acids Research", "preferred": true, "title": "Enrichr-KG: bridging enrichment analysis across multiple libraries", "year": "2023"}], "repository": "https://github.com/MaayanLab/enrichr-kg", "taxon": ["NCBITaxon:9606"]}