HumanNet
HumanNet is a probabilistic functional gene network for Homo sapiens that integrates genomic and proteomic data from multiple sources to predict functional relationships between genes. The network uses a modified Bayesian integration approach to combine evidence from diverse data types including protein-protein interactions, gene co-expression, phylogenetic profiling, and literature mining. HumanNet provides confidence scores for gene-gene functional linkages and can be used for gene function prediction, disease gene prioritization, and pathway analysis.
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