SPOKE-OKN
The spoke-okn (SPOKE Open Knowledge Network) KG is a comprehensive biomedical and environmental health knowledge graph that integrates diverse data across genomics, environmental science, and public health.
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{"activity_status": "active", "category": "KnowledgeGraph", "collection": ["okn"], "contacts": [{"category": "Individual", "contact_details": [{"contact_type": "email", "value": "sergio.baranzini@ucsf.edu"}, {"contact_type": "github", "value": "baranzini-lab"}], "label": "Sergio Baranzini"}], "creation_date": "2026-03-30T00:00:00Z", "description": "The spoke-okn (SPOKE Open Knowledge Network) KG is a comprehensive biomedical and environmental health knowledge graph that integrates diverse data across genomics, environmental science, and public health.", "domains": ["biomedical", "genomics", "clinical", "precision medicine", "pharmacology"], "evaluation_page": "resource/spoke-okn/spoke-okn_eval_automated.html", "homepage_url": "https://spoke.ucsf.edu", "id": "spoke-okn", "last_modified_date": "2026-05-31T00:00:00Z", "layout": "resource_detail", "license": {"id": "https://spoke.rbvi.ucsf.edu/docs/licenses.html", "label": "Multiple licenses (see individual data sources)"}, "name": "SPOKE-OKN", "products": [{"category": "ProgrammingInterface", "description": "SPARQL endpoint for SPOKE-OKN", "format": "http", "id": "spoke-okn.sparql", "name": "SPOKE-OKN SPARQL", "original_source": [{"relation_type": "prov:hadPrimarySource", "source": "spoke-okn"}], "product_url": "https://apps.okn.us/spoke-okn/sparql"}, {"category": "ProgrammingInterface", "description": "Triple Pattern Fragments endpoint for SPOKE-OKN", "format": "http", "id": "spoke-okn.tpf", "name": "SPOKE-OKN TPF", "original_source": [{"relation_type": "prov:hadPrimarySource", "source": "spoke-okn"}], "product_url": "https://apps.okn.us/ldf/spoke-okn"}], "publications": [{"authors": ["John H Morris", "Karthik Soman", "Rabia E Akbas", "Xiaoyuan Zhou", "Brett Smith", "Elaine C Meng", "Conrad C Huang", "Gabriel Cerono", "Gregory Schenk", "Angela Rizk-Jackson", "A Harroud", "Lindsey Sanders", "Simon V Costes", "Kaustuv Bharat", "Amit Chakraborty", "Alex Pico", "T Mardirossian", "Michael Keiser", "Atul Tang", "J Hardi", "Y Shi", "Mark Musen", "S Israni", "Sui Huang", "Peter W Rose", "Charlotte A Nelson", "Sergio E Baranzini"], "id": "https://doi.org/10.1093/bioinformatics/btad080", "journal": "Bioinformatics", "preferred": true, "title": "The scalable precision medicine open knowledge engine (SPOKE): a massive knowledge graph of biomedical information", "year": "2023"}, {"authors": ["Sergio E Baranzini", "Katy Borner", "John Morris", "Charlotte A Nelson", "Karthik Soman", "Erica Schleimer", "Michael Keiser", "Atul Butte", "Mark Musen", "Sui Huang"], "id": "https://doi.org/10.1002/aaai.12037", "journal": "AI Magazine", "title": "A biomedical open knowledge network harnesses the power of AI to understand deep human biology", "year": "2022"}], "repository": "https://github.com/baranzini-lab/SPOKE"}