is an Aggregator.
MINT (The Molecular INTeraction database) is a public and open source database focusing on experimentally verified protein-protein interactions mined from the scientific literature by expert curators. Molecular interactions are annotated according to international PSI-MI standards and follow the PSI-MI controlled vocabulary. MINT is a founder and main member of the IMEx consortium and provides data that is integrated into the IntAct database as part of a single non-redundant open access dataset. As an ELIXIR Core Data Resource and Global Core Biodata Resource, MINT contains over 139,000 interactions involving 27,800+ interactors from 676 organisms extracted from 6,500+ publications.
proteomics, biomedical, systems biology, biological systems
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| mint.portal | MINT Web Portal | mint.bio.uniroma2.it | GraphicalInterface | http | Web interface for browsing, searching... |
| mint.mitab.all ⚠ | MINT MITAB Full Dataset | * | Product | psi_mi_mitab | Complete MINT dataset in PSI-MI MITAB... |
| mint.mitab.human ⚠ | MINT Human Interactions | species:human | Product | psi_mi_mitab | Human protein interactions from MINT ... |
| mint.mitab.mouse ⚠ | MINT Mouse Interactions | species:mouse | Product | psi_mi_mitab | Mouse protein interactions from MINT ... |
| mint.psicquic | MINT PSICQUIC Web Service | webservices | ProgrammingInterface | ❔ | PSICQUIC SOAP and REST web services f... |
| mint.advanced.search | MINT Advanced Search | advanced-search | GraphicalInterface | http | Advanced search interface for queryin... |
| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| irefindex.database | iRefIndex Database | ❔ | Product | psi_mi_mitab | Historical consolidated protein inter... |
| string.protein.links | STRING Protein Links | protein.links.v12.0.txt.gz (128.7 GB) | GraphProduct | txt | protein network data (full network, s... |
| string.protein.links.detailed | STRING Protein Links Detailed | protein.links.detailed.v12.0.txt.gz (189.6 GB) | GraphProduct | txt | protein network data (full network, i... |
| string.protein.links.full | STRING Protein Links Full | protein.links.full.v12.0.txt.gz (199.6 GB) | GraphProduct | txt | protein network data (full network, i... |
| string.protein.physical.links | STRING Protein Physical Links | protein.physical.links.v12.0.txt.gz (11.1 GB) | GraphProduct | txt | protein network data (physical subnet... |
| string.protein.physical.links.detailed | STRING Protein Physical Links Detailed | protein.physical.links.detailed.v12.0.txt.gz (13.8 GB) | GraphProduct | txt | protein network data (physical subnet... |
| string.protein.physical.links.full | STRING Protein Physical Links Full | protein.physical.links.full.v12.0.txt.gz (14.5 GB) | GraphProduct | txt | protein network data (physical subnet... |
| string.cog.links | STRING COG Links | COG.links.v12.0.txt.gz (176.8 MB) | GraphProduct | txt | association scores between orthologou... |
| string.cog.links.detailed | STRING COG Links Detailed | COG.links.detailed.v12.0.txt.gz (238.7 MB) | GraphProduct | txt | association scores (incl. subscores p... |
| string.database | STRING Database Network Schema | network_schema.v12.0.sql.gz (262.2 GB) | GraphProduct | ❔ | full database, part II: the networks ... |
MINT (The Molecular INTeraction database) is a comprehensive public repository for experimentally verified protein-protein interactions curated from peer-reviewed scientific literature. Developed and maintained by the University of Rome Tor Vergata, MINT serves as a critical resource for researchers studying molecular interactions and protein networks.
MINT is a founder and one of the main members of the International Molecular Exchange (IMEx) consortium. IMEx resources have merged their efforts to provide comprehensively annotated molecular interaction data integrated into a single, non-redundant, open access dataset stored and available through the IntAct database at EBI.
Interactive portal for:
Based on Lucene’s syntax with support for:
brca2, "pull down")species:human, detmethod:"two hybrid*")brca2 AND rpa1)Tab-delimited format including:
Structured XML format with comprehensive metadata and cross-references for integration with other tools and databases.
MINT data includes extensive cross-references to:
Users are encouraged to cite:
All data available under Creative Commons Attribution 4.0 International (CC BY 4.0) license, allowing free use with proper attribution.
MINT was established as one of the first comprehensive protein interaction databases and has been continuously maintained and updated since 2002. As a founding member of IMEx, MINT has played a crucial role in establishing standards for molecular interaction data annotation and exchange.
MINT continues to:
Created: October 31, 2025 | Last modified: October 31, 2025