Enum: DomainEnum

A domain that a resource is relevant to. Each domain maps, where possible, to a concept in an external controlled vocabulary (Medical Subject Headings, MeSH; the NCI Thesaurus, NCIT; or EDAM) via the permissible value’s meaning. Domains form a two-level hierarchy. A specific domain names its broader domain with is_a, and a resource that lists a specific domain also lists the broader one.

URI: kgr:DomainEnum

Permissible Values

Value Meaning Is A Description
adverse outcome pathways MESH:D000073931 toxicology Adverse outcome pathways linking molecular initiating events to adverse outco…
aging MESH:D000375 biological systems Aging and longevity, including cellular senescence
agriculture MESH:D000383   The agricultural and food sciences, including crop and animal production, pla…
air pollution MESH:D000397 environment Air quality and emissions to air
anatomy and development MESH:D000715   The anatomy and development of organisms, including their structure, morpholo…
biodiversity MESH:D044822 organisms The variety of life, including species occurrence, conservation status, and i…
biological systems MESH:D001690   The biological sciences broadly, including cellular and molecular biology and…
biomedical MESH:D035843   The biomedical sciences broadly, spanning the study of biological systems in …
cancer MESH:D009369 biomedical Cancer and other neoplasms, including tumor genomics, cancer cell lines, onco…
cardiovascular disease MESH:D002318 biomedical Diseases of the heart and blood vessels, including hypertension
cell biology MESH:D003585 biological systems Cells and cell types, including cell lines, cell markers, and subcellular str…
cheminformatics MESH:D000080911 chemistry and biochemistry Computational representation, identification, and classification of chemical …
chemistry and biochemistry MESH:D002621   The chemical and biochemical sciences, including the structure, properties, a…
climate MESH:D002980 environment Climate and climate change, including climate models and drought
clinical MESH:D015510   The clinical sciences concerned with the care of patients, including clinical…
clinical coding MESH:D059019 clinical Clinical terminologies and code sets for diagnoses, procedures, observations,…
clinical trials MESH:D002986 clinical Clinical trials, including trial registries and the data standards used to re…
criminal justice MESH:D003416 public health Crime, courts, and the justice system, including crime reporting and court re…
diabetes mellitus MESH:D003920 biomedical Diabetes mellitus, including type 1 and type 2 diabetes and the pancreatic is…
disasters MESH:D004190 public health Disasters and emergencies, including disaster declarations, humanitarian resp…
disease registries MESH:D012042 public health Population-based registries of disease cases, such as cancer registries
domestic animals MESH:D000829 organisms Domestic animals, including companion animals and livestock breeds
drug discovery MESH:D055808   The process of identifying and developing new candidate medications, includin…
drug interactions MESH:D004347 pharmacology Interactions between drugs and between drugs and foods or natural products
drug repositioning MESH:D058492 drug discovery The discovery of new indications for existing drugs, including computational …
ecology MESH:D004463 environment The interactions of organisms with each other and their environment, includin…
electronic health records MESH:D057286 clinical Electronic health records and observational health data derived from them
environment MESH:D004777   The environment and ecosystems, including ecology and environmental health
environmental exposure MESH:D004781 environment Exposure of people and organisms to environmental agents and the health effec…
enzymes MESH:D004798 chemistry and biochemistry Enzymes, including their classification, reactions, and catalytic mechanisms
epidemiology MESH:D004813 public health The distribution and determinants of disease in populations, including diseas…
epigenomics MESH:D057890 genomics Genome-wide chromatin state and organization, including chromatin conformatio…
food MESH:D005502 nutrition Foods, their composition, and their relationship to diet and health
gene expression profiling MESH:D020869 genomics Measurement of gene expression across tissues, cells, and conditions, includi…
gene regulation MESH:D005786 genomics The regulation of gene expression, including transcription factors, their bin…
general None   A general domain, not specific to any other category. It concerns resources t…
genetic variation MESH:D014644 genomics Germline and somatic genetic variants, including their frequencies, effects, …
genome-wide association studies MESH:D055106 genomics Genome-wide association studies and related statistical genetics, including Q…
genomics MESH:D023281   The study of genomes, including genome structure, evolution, function, mappin…
geographic information systems MESH:D040362 environment Geospatial data, including place names, administrative boundaries, and infras…
glycomics MESH:D054794 chemistry and biochemistry The study of glycans and glycoconjugates
high-throughput screening MESH:D057166 drug discovery Large-scale screening of chemical or genetic perturbations, including cell li…
host-pathogen interactions MESH:D054884 microbiology Interactions between pathogens and their hosts, including pathogen genomics a…
human populations MESH:D044382 organisms Human population groups, including ancestry, ethnicity, and demographic groups
humanities and cultural heritage MESH:D006809   The humanities and the cultural heritage domain, including art history, archi…
immunology MESH:D000486   The study of the immune system, including its structure and function, disorde…
infectious disease MESH:D003141 biomedical Infectious diseases, including their pathogens, transmission, epidemiology, d…
information technology MESH:D000073256   The information technology and informatics sciences, including software, comp…
insects MESH:D007313 organisms Insects, including their anatomy, behavior, and genomics
literature MESH:D011642   The literature and publications of a domain
machine learning MESH:D000069550 information technology Machine learning and artificial intelligence, including AI-ready data and mod…
medical imaging MESH:D003952   Techniques and processes for creating visual representations of the interior …
mental disorders MESH:D001523 neuroscience Mental and psychiatric disorders, including substance use disorders
metabolism MESH:D008660 pathways Metabolic pathways and genome-scale metabolic network reconstructions
metabolomics MESH:D055432 chemistry and biochemistry The large-scale study of metabolites and lipids, including mass spectrometry …
metadata MESH:D000071253 information technology Metadata vocabularies and standards for describing resources, datasets, and p…
microbiology MESH:D008829   The microbiological sciences, including the study of microbial communities (m…
microbiome MESH:D064307 microbiology Microbial communities, including host-associated microbiomes and metagenomes
model organisms edam:topic_0621 organisms Model organisms and the databases that serve their research communities
molecular evolution MESH:D019143 genomics The evolution of genes and proteins, including orthology, gene families, and …
natural language processing MESH:D009323 literature Text mining and natural language processing of the literature, including text…
natural products NCIT:C1907 chemistry and biochemistry Compounds derived from plants, microorganisms, or animals, including traditio…
neurodegenerative disease MESH:D019636 neuroscience Neurodegenerative diseases, including Alzheimer disease and related dementias
neuroscience MESH:D009488   The scientific study of the nervous system, including brain structure, functi…
non-coding RNA MESH:D022661 genomics RNAs that are not translated into protein, including microRNAs, long non-codi…
nutrition MESH:D052756   The nutritional sciences, including diet and metabolomics
organisms NCIT:C14250   Specific organisms or taxa
other None   Another domain not defined here
pathways MESH:D053858   Biological pathways, including metabolic, signaling, and regulatory networks …
pharmacogenomics MESH:D010597 pharmacology The influence of genetic variation on drug response
pharmacology MESH:D010600   The study of how drugs interact with biological systems, including drug disco…
pharmacovigilance MESH:D060735 pharmacology The monitoring of drug and device safety, including adverse event reports and…
phenotype MESH:D010641   The phenotypes of organisms
plants MESH:D010944 organisms Plants, including crops and their anatomy, traits, and genomics
population genetics MESH:D005828 genomics Genetic variation within and between populations, including human ancestry
post-translational modification MESH:D011499 proteomics Post-translational modifications of proteins, such as phosphorylation
precision medicine MESH:D057285   An approach to disease treatment and prevention that takes into account indiv…
protein domains MESH:D000072417 proteomics Protein families, domains, and functional sites
protein interactions MESH:D060066 proteomics Physical interactions between proteins, including protein complexes
protein structure MESH:D011487 proteomics The three-dimensional structure of proteins, whether determined experimentall…
proteomics MESH:D040901   The large-scale study of proteins, their structures, functions, and interacti…
public health MESH:D011634   The science of protecting and improving the health of people and their commun…
rare disease MESH:D035583 biomedical Rare diseases, including rare Mendelian and other genetic disorders, their ph…
research funding NCIT:C17090   The funding and administration of research, including research projects, gran…
scholarly communication MESH:D000073820 literature Scholarly publications and their metadata, including citations, authors, and …
signal transduction MESH:D015398 pathways Signaling pathways and networks that transmit signals within and between cells
single-cell analysis MESH:D059010 biological systems Data and methods that measure molecules in individual cells, including single…
social determinants of health MESH:D064890 public health The social and economic conditions that shape health, including housing, inco…
software MESH:D012984 information technology Software, including package registries, software supply chains, and vulnerabi…
sustainability MESH:D000076502 environment Sustainability and environmental, social, and governance (ESG) reporting
systems biology MESH:D049490   The computational and mathematical analysis of complex biological systems and…
taxonomy NCIT:C17469 organisms The naming and classification of organisms and the relationships among taxa
toxicology MESH:D014116   The study of the adverse effects of chemicals on living organisms
transportation MESH:D014186   Transportation and transport infrastructure, including railway, road, air, an…
vaccines MESH:D014612 immunology Vaccines and vaccination, including vaccine adverse events
water resources MESH:D062066 environment Surface water, groundwater, drinking water, and hydrology
wildfires MESH:D000075923 environment Wildfires and their burn severity and smoke
stub None   This is not a domain, but rather a category for resources that are not yet ca…

Slots

Name Description
domains The domain(s) that the resource is relevant to

Identifier and Mapping Information

Schema Source

  • from schema: https://w3id.org/knowledge-graph-hub/kg_registry_schema

LinkML Source

```yaml name: DomainEnum description: A domain that a resource is relevant to. Each domain maps, where possible, to a concept in an external controlled vocabulary (Medical Subject Headings, MeSH; the NCI Thesaurus, NCIT; or EDAM) via the permissible value's `meaning`. Domains form a two-level hierarchy. A specific domain names its broader domain with `is_a`, and a resource that lists a specific domain also lists the broader one. from_schema: https://w3id.org/knowledge-graph-hub/kg_registry_schema permissible_values: adverse outcome pathways: text: adverse outcome pathways description: Adverse outcome pathways linking molecular initiating events to adverse outcomes. meaning: MESH:D000073931 is_a: toxicology aging: text: aging description: Aging and longevity, including cellular senescence. meaning: MESH:D000375 is_a: biological systems agriculture: text: agriculture description: The agricultural and food sciences, including crop and animal production, plant science, and food production, processing, and preservation. meaning: MESH:D000383 air pollution: text: air pollution description: Air quality and emissions to air. meaning: MESH:D000397 is_a: environment anatomy and development: text: anatomy and development description: The anatomy and development of organisms, including their structure, morphology, and developmental biology. meaning: MESH:D000715 biodiversity: text: biodiversity description: The variety of life, including species occurrence, conservation status, and invasive species. meaning: MESH:D044822 is_a: organisms biological systems: text: biological systems description: The biological sciences broadly, including cellular and molecular biology and other biological disciplines not better described by a more specific domain. meaning: MESH:D001690 biomedical: text: biomedical description: The biomedical sciences broadly, spanning the study of biological systems in the context of health and disease. Use a more specific domain (e.g., clinical) where one applies. meaning: MESH:D035843 cancer: text: cancer description: Cancer and other neoplasms, including tumor genomics, cancer cell lines, oncology treatment, and cancer registries. meaning: MESH:D009369 is_a: biomedical cardiovascular disease: text: cardiovascular disease description: Diseases of the heart and blood vessels, including hypertension. meaning: MESH:D002318 is_a: biomedical cell biology: text: cell biology description: Cells and cell types, including cell lines, cell markers, and subcellular structures. meaning: MESH:D003585 is_a: biological systems cheminformatics: text: cheminformatics description: Computational representation, identification, and classification of chemical structures. meaning: MESH:D000080911 is_a: chemistry and biochemistry chemistry and biochemistry: text: chemistry and biochemistry description: The chemical and biochemical sciences, including the structure, properties, and reactions of chemical compounds. meaning: MESH:D002621 climate: text: climate description: Climate and climate change, including climate models and drought. meaning: MESH:D002980 is_a: environment clinical: text: clinical description: The clinical sciences concerned with the care of patients, including clinical trials, patient data, and diagnosis and treatment of disease. meaning: MESH:D015510 clinical coding: text: clinical coding description: Clinical terminologies and code sets for diagnoses, procedures, observations, and medications. meaning: MESH:D059019 is_a: clinical clinical trials: text: clinical trials description: Clinical trials, including trial registries and the data standards used to report them. meaning: MESH:D002986 is_a: clinical criminal justice: text: criminal justice description: Crime, courts, and the justice system, including crime reporting and court records. meaning: MESH:D003416 is_a: public health diabetes mellitus: text: diabetes mellitus description: Diabetes mellitus, including type 1 and type 2 diabetes and the pancreatic islet biology that underlies them. meaning: MESH:D003920 is_a: biomedical disasters: text: disasters description: Disasters and emergencies, including disaster declarations, humanitarian response, and critical infrastructure. meaning: MESH:D004190 is_a: public health disease registries: text: disease registries description: Population-based registries of disease cases, such as cancer registries. meaning: MESH:D012042 is_a: public health domestic animals: text: domestic animals description: Domestic animals, including companion animals and livestock breeds. meaning: MESH:D000829 is_a: organisms drug discovery: text: drug discovery description: The process of identifying and developing new candidate medications, including target identification, validation, and compound screening. meaning: MESH:D055808 drug interactions: text: drug interactions description: Interactions between drugs and between drugs and foods or natural products. meaning: MESH:D004347 is_a: pharmacology drug repositioning: text: drug repositioning description: The discovery of new indications for existing drugs, including computational repurposing methods and their benchmarks. meaning: MESH:D058492 is_a: drug discovery ecology: text: ecology description: The interactions of organisms with each other and their environment, including ecological networks. meaning: MESH:D004463 is_a: environment electronic health records: text: electronic health records description: Electronic health records and observational health data derived from them. meaning: MESH:D057286 is_a: clinical environment: text: environment description: The environment and ecosystems, including ecology and environmental health. meaning: MESH:D004777 environmental exposure: text: environmental exposure description: Exposure of people and organisms to environmental agents and the health effects of those exposures. meaning: MESH:D004781 is_a: environment enzymes: text: enzymes description: Enzymes, including their classification, reactions, and catalytic mechanisms. meaning: MESH:D004798 is_a: chemistry and biochemistry epidemiology: text: epidemiology description: The distribution and determinants of disease in populations, including disease surveillance and outbreaks. meaning: MESH:D004813 is_a: public health epigenomics: text: epigenomics description: Genome-wide chromatin state and organization, including chromatin conformation and regulatory element annotation. meaning: MESH:D057890 is_a: genomics food: text: food description: Foods, their composition, and their relationship to diet and health. meaning: MESH:D005502 is_a: nutrition gene expression profiling: text: gene expression profiling description: Measurement of gene expression across tissues, cells, and conditions, including transcriptomic signatures. meaning: MESH:D020869 is_a: genomics gene regulation: text: gene regulation description: The regulation of gene expression, including transcription factors, their binding sites, promoters, and enhancers. meaning: MESH:D005786 is_a: genomics general: text: general description: A general domain, not specific to any other category. It concerns resources that are broadly applicable across multiple domains, including upper-level and cross-domain resources. genetic variation: text: genetic variation description: Germline and somatic genetic variants, including their frequencies, effects, and clinical interpretation. meaning: MESH:D014644 is_a: genomics genome-wide association studies: text: genome-wide association studies description: Genome-wide association studies and related statistical genetics, including QTL and Mendelian randomization analyses. meaning: MESH:D055106 is_a: genomics genomics: text: genomics description: The study of genomes, including genome structure, evolution, function, mapping, and editing. meaning: MESH:D023281 geographic information systems: text: geographic information systems description: Geospatial data, including place names, administrative boundaries, and infrastructure maps. meaning: MESH:D040362 is_a: environment glycomics: text: glycomics description: The study of glycans and glycoconjugates. meaning: MESH:D054794 is_a: chemistry and biochemistry high-throughput screening: text: high-throughput screening description: Large-scale screening of chemical or genetic perturbations, including cell line sensitivity and perturbation profiling. meaning: MESH:D057166 is_a: drug discovery host-pathogen interactions: text: host-pathogen interactions description: Interactions between pathogens and their hosts, including pathogen genomics and virulence. meaning: MESH:D054884 is_a: microbiology human populations: text: human populations description: Human population groups, including ancestry, ethnicity, and demographic groups. meaning: MESH:D044382 is_a: organisms humanities and cultural heritage: text: humanities and cultural heritage description: The humanities and the cultural heritage domain, including art history, architecture, musicology, media and performing arts, archaeology, and history, along with the collections, archives, and museum holdings that document them. meaning: MESH:D006809 immunology: text: immunology description: The study of the immune system, including its structure and function, disorders, and therapeutic applications. meaning: MESH:D000486 infectious disease: text: infectious disease description: Infectious diseases, including their pathogens, transmission, epidemiology, diagnosis, and treatment. meaning: MESH:D003141 is_a: biomedical information technology: text: information technology description: The information technology and informatics sciences, including software, computational methods, simulation and modeling, and digital health technologies. meaning: MESH:D000073256 insects: text: insects description: Insects, including their anatomy, behavior, and genomics. meaning: MESH:D007313 is_a: organisms literature: text: literature description: The literature and publications of a domain. meaning: MESH:D011642 machine learning: text: machine learning description: Machine learning and artificial intelligence, including AI-ready data and models. meaning: MESH:D000069550 is_a: information technology medical imaging: text: medical imaging description: Techniques and processes for creating visual representations of the interior of a body for clinical analysis and medical intervention. meaning: MESH:D003952 mental disorders: text: mental disorders description: Mental and psychiatric disorders, including substance use disorders. meaning: MESH:D001523 is_a: neuroscience metabolism: text: metabolism description: Metabolic pathways and genome-scale metabolic network reconstructions. meaning: MESH:D008660 is_a: pathways metabolomics: text: metabolomics description: The large-scale study of metabolites and lipids, including mass spectrometry and NMR data. meaning: MESH:D055432 is_a: chemistry and biochemistry metadata: text: metadata description: Metadata vocabularies and standards for describing resources, datasets, and provenance. meaning: MESH:D000071253 is_a: information technology microbiology: text: microbiology description: The microbiological sciences, including the study of microbial communities (microbiomes) and their influence on hosts and environments. meaning: MESH:D008829 microbiome: text: microbiome description: Microbial communities, including host-associated microbiomes and metagenomes. meaning: MESH:D064307 is_a: microbiology model organisms: text: model organisms description: Model organisms and the databases that serve their research communities. meaning: edam:topic_0621 is_a: organisms molecular evolution: text: molecular evolution description: The evolution of genes and proteins, including orthology, gene families, and comparative analysis. meaning: MESH:D019143 is_a: genomics natural language processing: text: natural language processing description: Text mining and natural language processing of the literature, including text-mined knowledge graphs and annotated corpora. meaning: MESH:D009323 is_a: literature natural products: text: natural products description: Compounds derived from plants, microorganisms, or animals, including traditional medicines. meaning: NCIT:C1907 is_a: chemistry and biochemistry neurodegenerative disease: text: neurodegenerative disease description: Neurodegenerative diseases, including Alzheimer disease and related dementias. meaning: MESH:D019636 is_a: neuroscience neuroscience: text: neuroscience description: The scientific study of the nervous system, including brain structure, function, and disorders. meaning: MESH:D009488 non-coding RNA: text: non-coding RNA description: RNAs that are not translated into protein, including microRNAs, long non-coding RNAs, and ribosomal and transfer RNAs. meaning: MESH:D022661 is_a: genomics nutrition: text: nutrition description: The nutritional sciences, including diet and metabolomics. meaning: MESH:D052756 organisms: text: organisms description: Specific organisms or taxa. meaning: NCIT:C14250 other: text: other description: Another domain not defined here. pathways: text: pathways description: Biological pathways, including metabolic, signaling, and regulatory networks that control cellular processes. meaning: MESH:D053858 pharmacogenomics: text: pharmacogenomics description: The influence of genetic variation on drug response. meaning: MESH:D010597 is_a: pharmacology pharmacology: text: pharmacology description: The study of how drugs interact with biological systems, including drug discovery, development, and therapeutic uses. meaning: MESH:D010600 pharmacovigilance: text: pharmacovigilance description: The monitoring of drug and device safety, including adverse event reports and side effects. meaning: MESH:D060735 is_a: pharmacology phenotype: text: phenotype description: The phenotypes of organisms. meaning: MESH:D010641 plants: text: plants description: Plants, including crops and their anatomy, traits, and genomics. meaning: MESH:D010944 is_a: organisms population genetics: text: population genetics description: Genetic variation within and between populations, including human ancestry. meaning: MESH:D005828 is_a: genomics post-translational modification: text: post-translational modification description: Post-translational modifications of proteins, such as phosphorylation. meaning: MESH:D011499 is_a: proteomics precision medicine: text: precision medicine description: An approach to disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle. meaning: MESH:D057285 protein domains: text: protein domains description: Protein families, domains, and functional sites. meaning: MESH:D000072417 is_a: proteomics protein interactions: text: protein interactions description: Physical interactions between proteins, including protein complexes. meaning: MESH:D060066 is_a: proteomics protein structure: text: protein structure description: The three-dimensional structure of proteins, whether determined experimentally or predicted. meaning: MESH:D011487 is_a: proteomics proteomics: text: proteomics description: The large-scale study of proteins, their structures, functions, and interactions. meaning: MESH:D040901 public health: text: public health description: The science of protecting and improving the health of people and their communities, including epidemiology, population health, and the social determinants of health. meaning: MESH:D011634 rare disease: text: rare disease description: Rare diseases, including rare Mendelian and other genetic disorders, their phenotypes, genes, and treatments. meaning: MESH:D035583 is_a: biomedical research funding: text: research funding description: The funding and administration of research, including research projects, grants and their payments, funding programmes, the organizations that fund or carry out research, and the outputs attributed to that funding. meaning: NCIT:C17090 scholarly communication: text: scholarly communication description: Scholarly publications and their metadata, including citations, authors, and research contributions. meaning: MESH:D000073820 is_a: literature signal transduction: text: signal transduction description: Signaling pathways and networks that transmit signals within and between cells. meaning: MESH:D015398 is_a: pathways single-cell analysis: text: single-cell analysis description: Data and methods that measure molecules in individual cells, including single-cell and spatial atlases. meaning: MESH:D059010 is_a: biological systems social determinants of health: text: social determinants of health description: The social and economic conditions that shape health, including housing, income, services, and rurality. meaning: MESH:D064890 is_a: public health software: text: software description: Software, including package registries, software supply chains, and vulnerabilities. meaning: MESH:D012984 is_a: information technology sustainability: text: sustainability description: Sustainability and environmental, social, and governance (ESG) reporting. meaning: MESH:D000076502 is_a: environment systems biology: text: systems biology description: The computational and mathematical analysis of complex biological systems and their interactions. meaning: MESH:D049490 taxonomy: text: taxonomy description: The naming and classification of organisms and the relationships among taxa. meaning: NCIT:C17469 is_a: organisms toxicology: text: toxicology description: The study of the adverse effects of chemicals on living organisms. meaning: MESH:D014116 transportation: text: transportation description: Transportation and transport infrastructure, including railway, road, air, and maritime networks, the assets and parameters that describe them, and the movement of people and goods over them. meaning: MESH:D014186 vaccines: text: vaccines description: Vaccines and vaccination, including vaccine adverse events. meaning: MESH:D014612 is_a: immunology water resources: text: water resources description: Surface water, groundwater, drinking water, and hydrology. meaning: MESH:D062066 is_a: environment wildfires: text: wildfires description: Wildfires and their burn severity and smoke. meaning: MESH:D000075923 is_a: environment stub: text: stub description: This is not a domain, but rather a category for resources that are not yet categorized and exist only as a placeholder. ```