aragorn

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ARAGORN (Autonomous Relay Agent for Generation Of Ranked Networks) is an NCATS Translator Autonomous Relay Agent (ARA) that performs query operations by compiling and ranking data from multiple ARAGORN-affiliated knowledge provider services. ARAGORN acts as an intermediary between user queries and underlying knowledge providers, aggregating results, performing inference, and ranking answers based on evidence and confidence scores. It implements the Translator Reasoner API (TRAPI) standard for biomedical question-answering.

Domains

biomedical, translational, information technology

License

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Homepage

aragorn

Repository

GitHub

Infores ID

infores:aragorn

FAIRsharing ID

Unknown

Product Summary

Products

From this Resource
ID Name URL Category Format Description
aragorn.api ARAGORN API aragorn.renci.org ProgrammingInterface http TRAPI-compliant API for biomedical qu...
aragorn.ui ARAGORN User Interface ui.transltr.io GraphicalInterface http Web interface for querying ARAGORN

Details

ARAGORN

Overview

ARAGORN (Autonomous Relay Agent for Generation Of Ranked Networks) is an NCATS Translator Autonomous Relay Agent (ARA) that performs query operations by compiling and ranking data from multiple knowledge provider services.

As a key component of the Translator ecosystem, ARAGORN acts as an intelligent intermediary that receives biomedical questions, queries multiple underlying knowledge providers, aggregates results, performs inference reasoning, and returns ranked answers with supporting evidence.

Key Features

  • Multi-Source Integration: Queries multiple knowledge providers simultaneously
  • Answer Ranking: Ranks and scores results based on evidence quality and confidence
  • Inference Reasoning: Performs logical inference to discover indirect relationships
  • TRAPI Compliance: Implements the Translator Reasoner API standard
  • Result Provenance: Tracks and reports evidence sources for all answers
  • Subgraph Construction: Builds knowledge graphs connecting query concepts

Architecture

ARAGORN operates as an intermediary layer in the Translator architecture:

  • Receives biomedical questions in TRAPI format
  • Distributes queries to affiliated knowledge providers
  • Aggregates and normalizes results
  • Applies ranking algorithms based on evidence
  • Returns structured answers with provenance

Products

ARAGORN API

TRAPI-compliant RESTful API endpoint for submitting biomedical questions and receiving ranked answers from integrated knowledge sources.

ARAGORN User Interface

Web-based interface accessible through the Translator UI for interactive exploration of ARAGORN query capabilities.

Information Resource ID

This resource has the Information Resource identifier: infores:aragorn

Repository

Source code and documentation: https://github.com/ranking-agent/aragorn

Domains

  • Biomedical
  • Translational
  • Information Technology

Tags

  • NCATS Translator

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Created: November 05, 2025 | Last modified: November 05, 2025