biodata-catalyst

is an Aggregator.

NHLBI BioData Catalyst (BDC) is the cloud data ecosystem of the National Heart, Lung, and Blood Institute. It hosts more than 500 heart, lung, blood and sleep datasets (over 5 PB), including TOPMed whole-genome sequencing with linked phenotypes, RECOVER, HeartShare and National Sleep Research Resource studies, and links them to data discovery (PIC-SURE), a Gen3 data commons, cloud analysis workspaces (Seven Bridges and Terra) and the TOPMed Imputation Server. Most individual-level data are controlled access and require an eRA Commons login and an approved dbGaP data access request; a small set of open-access studies can be explored without authorization.

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Repository

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External IDs

No external IDs available

Product Summary

Contacts

National Heart, Lung, and Blood Institute

URL: https://biodatacatalyst.nhlbi.nih.gov/contact

Publications

Building a collaborative cloud platform to accelerate heart, lung, blood, and sleep research Preferred

Products

From this Resource

ID	Name	URL	Category	Format	Description
biodata-catalyst.portal	BioData Catalyst Portal	biodatacatalyst.nhlbi.nih.gov	Graphical Interface	http	BioData Catalyst portal, the entry po...
biodata-catalyst.picsure	BDC PIC-SURE	picsure.biodatacatalyst.nhlbi.nih.gov	Graphical Interface	http	BDC PIC-SURE (Patient Information Com...
biodata-catalyst.picsure-api ⚠	BDC PIC-SURE API	picsure	Programming Interface	http	PIC-SURE REST API for programmatic qu...
biodata-catalyst.gen3	BDC Gen3 Data Commons	gen3.biodatacatalyst.nhlbi.nih.gov	Graphical Interface	http	BDC Gen3 data commons for browsing st...
biodata-catalyst.imputation-server	TOPMed Imputation Server	imputation.biodatacatalyst.nhlbi.nih.gov	Process	http	TOPMed Imputation Server, a web servi...
biodata-catalyst.analysis-platforms	BDC Analysis Platforms (Terra and Seven Bridges)	terra.biodatacatalyst.nhlbi.nih.gov	Graphical Interface	http	Cloud analysis workspaces available w...
biodata-catalyst.docs	BioData Catalyst Documentation	biodata-catalyst-documentation	Documentation	http	BDC user documentation covering accou...

Relevant Taxa

Human (NCBITaxon:9606)

Details

NHLBI BioData Catalyst

Overview

NHLBI BioData Catalyst (BDC) is a cloud-based ecosystem in which researchers find, access, share, store and compute on large heart, lung, blood and sleep (HLBS) datasets. It brings together separately developed platforms under shared authentication and authorization.

Data

More than 500 datasets and over 5 PB of data, many multi-modal
TOPMed whole-genome sequencing with linked clinical and omics data (over 100 datasets)
RECOVER (Long COVID), HeartShare and National Sleep Research Resource studies
Open-access studies (e.g. 1000 Genomes, BioLINCC training datasets) for exploration

Components

PIC-SURE: search and export of harmonized phenotype and genotype variables (web and API)
Gen3: data commons for study metadata and authorized file access
Seven Bridges and Terra: cloud analysis workspaces
TOPMed Imputation Server: genotype imputation against the TOPMed reference panel

Access

Most individual-level data are controlled access. Users sign in with an eRA Commons account, and access to each study follows its approved dbGaP data access request and data use limitations. No open license applies to hosted data.