biofactoid

is a Data Source.

Biofactoid is a web-based system that empowers authors to capture and share machine-readable summaries of the molecular-level interactions between genes, gene products, and chemical compounds described in their publications. Author-sourced pathway knowledge is grounded to standard identifiers and made openly available in computable formats for reuse in pathway and network analysis.

License

CC0 1.0

Homepage

biofactoid

Repository

GitHub

Infores ID

Unknown

FAIRsharing ID

Unknown

Product Summary

Products

From this Resource
ID Name URL Category Format Description
biofactoid.webapp Biofactoid Web Application biofactoid.org GraphicalInterface http Web application where authors create ...
biofactoid.documents Biofactoid Pathway Documents biofactoid.org Product json Openly downloadable author-contribute...
biofactoid.api Biofactoid API api ProgrammingInterface http Public API (documented via Swagger UI...
From other Resources
ID Name URL Category Format Relation Description
pathwaycommons.biopax Integrated BioPAX Model pc-biopax.owl.gz (1.6 GB) Product biopax was derived from PC v14 integrated BioPAX Level 3 unif...
pathwaycommons.downloads Pathway Commons Data Downloads v14 Product mixed was derived from Download directory for Pathway Common...
pathwaycommons.sif SIF Network Format pc-hgnc.sif.gz (9.4 MB) Product sif was derived from PC v14 Simple Interaction Format netw...
pathwaycommons.gmt GMT Gene Set Format pc-hgnc.gmt.gz (256.4 KB) Product was derived from PC v14 Gene Matrix Transposed gene se...
pathwaycommons.txt Extended SIF TXT Format pc-hgnc.txt.gz (110.3 MB) Product txt was derived from PC v14 tab-delimited extended SIF nod...

Details

Biofactoid

Overview

Biofactoid is a web-based system that lets authors capture and share machine-readable summaries of the molecular interactions described in their own publications. Authors specify networks of interactions among genes, gene products, and chemical compounds, which Biofactoid grounds to standard identifiers and makes openly available in computable form for downstream pathway and network analysis.

Key Features

  • Author-sourced curation: Researchers directly capture the interactions from their own papers rather than relying on third-party curators.
  • Machine-readable output: Documents are exportable in a native JSON format as well as the BioPAX and SBGNML community standards.
  • Open data: Contributed pathway data is released under CC0 (public domain).
  • Open source: The software is developed in the open under the MIT license.

Access

Development

Biofactoid is developed and maintained by the Bader Lab at the University of Toronto as part of the Pathway Commons project.

Citation

Wong JV, Franz M, Siper MC, et al. Science Forum: Author-sourced capture of pathway knowledge in computable form using Biofactoid. eLife (2021). doi:10.7554/eLife.68292

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Created: June 03, 2026 | Last modified: June 05, 2026