bioteque

is a Knowledge Graph.

A knowledge graph of biological entities and their associations that integrates and formats biomedical data as pre-calculated knowledge graph embeddings

Domains

health

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bioteque

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Product Summary

Products

From this Resource
ID Name URL Category Format Description
bioteque.embeddings Bioteque Embeddings embeddings Product Network embeddings of the Bioteque gr...
bioteque.code Bioteque code bioteque ProcessProduct Scripts used to preprocess and accomm...
bioteque.bqsupports BQsupports bqsupports ProcessProduct BQsupports is a tool to uncover biome...

Details

Bioteque Knowledge Graph

Bioteque is a knowledge graph that integrates multiple biomedical data sources into a comprehensive resource for biomedical research. It combines various types of biomedical data, including:

  • Chemical and pharmaceutical data
  • Gene and protein information
  • Disease and phenotype data
  • Cell line information
  • Tissue-specific data
  • Pathway information
  • Molecular interactions

The knowledge graph is structured around biological entities and their associations, with nodes representing entities (compounds, genes, diseases, etc.) and edges representing relationships between them. These relationships include regulatory interactions, physical interactions, genetic interactions, and other biological associations.

Embeddings

A key feature of Bioteque is the provision of pre-calculated knowledge graph embeddings. These embeddings represent the biological entities and their associations in a continuous vector space, allowing for computational analyses such as:

  • Similarity searches between biological entities
  • Prediction of novel associations
  • Drug repurposing
  • Multi-omics data integration

The embeddings are available for download and can be used for various computational biology applications without the need to process the raw data or construct the knowledge graph from scratch.

Data Sources

Bioteque integrates data from over 35 different biomedical resources, including:

  • Chemical databases (ChEBI, PubChem, DrugBank)
  • Genomic resources (CCLE, COSMIC, Depmap)
  • Protein interaction databases (STRING, IntAct, HuRI)
  • Pathway resources (Reactome, PROGENy)
  • Regulatory information (DoRothEA)
  • Disease associations (DisGeNET, Open Targets)
  • Tissue-specific data (GTEx, Human Protein Atlas)

This integration provides a unified view of biomedical knowledge that can be accessed through the Bioteque portal or used programmatically through the available embeddings.

Evaluation

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Created: March 09, 2025 | Last modified: September 10, 2025