is a Data Source.
The ENCODE Registry of candidate cis-Regulatory Elements (cCREs) is a curated annotation of regulatory regions in the human and mouse genomes derived from ENCODE and Roadmap Epigenomics data. Each cCRE is classified by its biochemical signature, including promoter-like, enhancer-like, and CTCF-bound elements based on DNase hypersensitivity, H3K4me3, H3K27ac, and CTCF ChIP-seq signals. The registry is explorable through the SCREEN (Search Candidate cis-Regulatory Elements by ENCODE) web portal, which lets users browse cCREs and their activity across cell types and tissues. cCREs/SCREEN are produced as part of the ENCODE project and serve as an upstream source for downstream resources such as GenomicKB.
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| ccre.screen | SCREEN Portal | screen.encodeproject.org | GraphicalInterface | ❔ | SCREEN (Search Candidate cis-Regulato... |
| ID | Name | URL | Category | Format | Relation | Description |
|---|---|---|---|---|---|---|
| genomickb.graph | GenomicKB Graph Dump | genomickb-a-knowledgebase-for-the-human-genome | GraphProduct | http | had primary source | GenomicKB 1.0 Neo4j Database Dump (Re... |
The ENCODE Registry of candidate cis-Regulatory Elements (cCREs) is a curated set of regulatory regions annotated across the human and mouse genomes. cCREs are derived from ENCODE and Roadmap Epigenomics assays and are classified by biochemical signature (promoter-like, enhancer-like, and CTCF-bound). The registry is part of the ENCODE project and is explored through the SCREEN web portal. It is an upstream source for GenomicKB.
SCREEN (Search Candidate cis-Regulatory Elements by ENCODE) web portal for browsing and searching the registry of candidate cis-Regulatory Elements in the human and mouse genomes.
URL: https://screen.encodeproject.org/
Created: June 18, 2026 | Last modified: June 18, 2026