is a Data Source.
Cell Model Passports is a curated database of preclinical cancer models, including cell lines and organoids, run by the Wellcome Sanger Institute as part of the Cancer Dependency Map at Sanger. For each model it holds relationships to other models, patient and clinical annotation, and genomic and functional datasets including mutations, copy number, RNA-seq expression, methylation, proteomics, CRISPR knockout screens, drug response, gene fusions and growth rates.
| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| cellmodelpassports.portal | Cell Model Passports Web Portal | cellmodelpassports.sanger.ac.uk | Graphical Interface | http | Cell Model Passports web portal for s... |
| cellmodelpassports.api | Cell Model Passports API | swagger | Programming Interface | http | JSON:API (v1.0) REST API for models, ... |
| cellmodelpassports.downloads | Cell Model Passports Downloads | downloads | Product | mixed | Downloads page listing current and ar... |
| cellmodelpassports.model_list | Cell Model Passports Model List | model_list_20260921.csv (935.1 KB) | Mapping | csv | Annotated list of all cell line and o... |
| cellmodelpassports.gene_identifiers | Cell Model Passports Gene Identifiers | gene_identifiers_20241212.csv (3.7 MB) | Mapping | csv | Gene identifier table mapping Cell Mo... |
| cellmodelpassports.mutations_all | Cell Model Passports All Mutations | mutations_all_20260724.zip (291.0 MB) | Product | csv | Combined somatic mutation calls from ... |
| cellmodelpassports.rnaseq_merged | Cell Model Passports Merged RNA-seq Expression | rnaseq_merged_20260323.zip (1.2 GB) | Product | csv | Processed RNA-seq gene expression for... |
| cellmodelpassports.proteomics | Cell Model Passports Proteomics | Proteomics_20250211.zip (126.0 MB) | Product | csv | Processed protein abundance (proteomi... |
| cellmodelpassports.crispr_fitness_scores | Cell Model Passports CRISPR Fitness Scores | Project_Score2_fitness_scores_Sanger_v2_Broad_21Q2_20250624.zip (189.7 MB) | Product | csv | Project Score CRISPR knockout gene fi... |
| cellmodelpassports.gdsc2_dose_response | GDSC2 Fitted Dose Response | GDSC2_fitted_dose_response_27Oct23.xlsx (21.1 MB) | Product | xlsx | GDSC2 fitted drug dose response value... |
Cell Model Passports is a curated database of preclinical cancer models, including cell lines and organoids. It is run by the Wellcome Sanger Institute as part of the Cancer Dependency Map at Sanger, and it includes models from the Human Cancer Model Initiative (HCMI) and RNA-seq data from the Broad DepMap. The API reported 2,266 models on 2026-10-03 (the 2019 paper described over 1,200).
For each model it holds relationships to other models, patient and clinical annotation, and genomic and functional datasets: mutations, copy number, RNA-seq expression, methylation, proteomics, CRISPR knockout screens (Project Score), drug response (GDSC), gene fusions and growth rates. The model list cross-references Cellosaurus RRIDs, COSMIC IDs, DepMap (Broad) IDs and CCLE names.
/download_files?include=groups.files)/swagger)Data are covered by the DepMap at Sanger Data Usage Policy, which grants a non-exclusive, non-transferable right to use data files for internal research and educational purposes and excludes resale and commercial services. The API documentation states that use is free for non-commercial purposes, with prior consent needed for commercial use.
Created: October 03, 2026 | Last modified: October 03, 2026