is a Data Source.
ChEA is a family of transcription factor enrichment resources developed by the Ma'ayan Lab, spanning the original ChIP Enrichment Analysis database and later ChEA2 and ChEA3 releases that assemble transcription factor target gene sets from ChIP-X experiments and other orthogonal omics data.
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| chea.portal | ChEA Explorer | chea3 | GraphicalInterface | http | Public ChEA3 web interface for transc... |
| chea.api | ChEA API | enrich | ProgrammingInterface | http | ChEA3 enrichment API for submitting g... |
| chea.libraries | ChEA Library Downloads | index.html#content4-13 | Product | http | Download catalog for ChEA3 transcript... |
| chea.docker ⚠ | ChEA3 Docker Image | chea3 | Product | mixed | Docker image for running the ChEA3 we... |
| ID | Name | URL | Category | Format | Relation | Description |
|---|---|---|---|---|---|---|
| chea-kg.portal | ChEA-KG Explorer | chea-kg | GraphicalInterface | http | was influenced by | Interactive ChEA3 web interface for t... |
| chea-kg.api | ChEA-KG API | enrich | ProgrammingInterface | http | was influenced by | ChEA3 API endpoint for submitting gen... |
| chea-kg.graph | ChEA-KG Database | ❔ | GraphProduct | neo4j | was influenced by | Neo4j knowledge graph integrating tra... |
| chea-kg.libraries | ChEA-KG Library Downloads | index.html#content4-13 | Product | http | was influenced by | Download catalog for ChEA3 transcript... |
| harmonizome.downloads | Harmonizome Downloads | download | Product | mixed | was derived from | Harmonizome 3.0 processed dataset dow... |
| harmonizome.kg-neo4j | Harmonizome Knowledge Graph Neo4j Database | harmonizome-kg.maayanlab.cloud | GraphProduct | neo4j | was derived from | Neo4j knowledge graph serialization o... |
ChEA is the Ma’ayan Lab’s transcription factor enrichment analysis resource family. The original ChEA database integrated genome-wide ChIP-X experiments to create transcription factor target gene sets, and later releases such as ChEA2 and ChEA3 expanded the available libraries, benchmarking datasets, and interactive analysis workflows.
The current public deployment is the ChEA3 web application and API. Its documented upstream libraries include ENCODE and ReMap ChIP-seq collections, literature-derived ChIP-seq target sets from earlier ChEA releases, GTEx and ARCHS4 coexpression libraries, Enrichr query co-occurrence libraries, GEO-derived single-transcription-factor perturbation benchmarks, and some TCGA-derived network views.
This KG-Registry entry treats ChEA, ChEA2, and ChEA3 as one canonical resource represented by the identifier chea.
Created: May 21, 2026 | Last modified: June 01, 2026