is a Data Source.
The Clinical Interpretation of Variants in Cancer (CIViC) knowledgebase is a free and open resource for public use that enables the interpretation of variants in cancer by providing community-curated information about the clinical significance of genomic variants.
biomedical, genomics, clinical, precision medicine, cancer, genetic variation
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| civic.site | CIViC Web Interface | civicdb.org | Graphical Interface | http | Web interface that allows searching, ... |
| civic.api.v2 | CIViC GraphQL API (V2) | graphiql | Programming Interface | http | GraphQL API for programmatic access t... |
| civic.api.v1 | CIViC REST API (V1 - Deprecated) | graphql | Programming Interface | http | REST API for programmatic access to t... |
| civic.data.features | CIViC Features (Nightly) | nightly-FeatureSummaries.tsv (167.3 KB) | Product | tsv | CIViC Feature summaries, nightly version |
| civic.data.variants | CIViC Variants (Nightly) | nightly-VariantSummaries.tsv (520.7 KB) | Product | tsv | CIViC Variant summaries, nightly version |
| civic.data.molecularprofile | CIViC Molecular Profiles (Nightly) | nightly-MolecularProfileSummaries.tsv (606.4 KB) | Product | tsv | CIViC Molecular Profile summaries, ni... |
| civic.data.evidence | CIViC Clinical Evidence (Nightly) | nightly-ClinicalEvidenceSummaries.tsv (3.5 MB) | Product | tsv | CIViC Clinical Evidence summaries, ni... |
| civic.data.variantgroups | CIViC Variant Groups (Nightly) | nightly-VariantGroupSummaries.tsv (10.2 KB) | Product | tsv | CIViC Variant Group summaries, nightl... |
| civic.data.assertions | CIViC Assertions (Nightly) | nightly-AssertionSummaries.tsv (111.3 KB) | Product | tsv | CIViC Assertion summaries, nightly ve... |
| civic.data.acceptedvariants | CIViC Accepted Variants (Nightly) | nightly-civic_accepted.vcf (1.2 MB) | Product | vcf | CIViC Accepted Variants, nightly version |
| civic.data.acceptedsubmittedvariants | CIViC Accepted and Submitted Variants (Nightly) | nightly-civic_accepted_and_submitted.vcf (2.9 MB) | Product | vcf | CIViC Accepted and Submitted Variants... |
| ID | Name | URL | Category | Format | Relation | Description |
|---|---|---|---|---|---|---|
| spoke.graph | SPOKE Graph | data-tools | Graph | http | had primary source | The SPOKE knowledge graph containing ... |
| obo-db-ingest.civic.gid.tsv | civic.gid Nodes TSV | civic.gid.tsv (34.0 KB) | Product | tsv | had primary source | civic.gid Nodes TSV |
| biomuta.dataset | BioMuta Cancer Mutation Dataset | latest | Product | csv | was derived from | Unified BioMuta cancer mutation datas... |
| genecards.web.interface | GeneCards Web Interface | www.genecards.org | Graphical Interface | http | had primary source | Web-based interface for searching and... |
| spoke-okn.graph | SPOKE-OKN Graph | spoke.ucsf.edu | Graph | ttl | was influenced by | The SPOKE-OKN knowledge graph, an OKN... |
| obo-db-ingest.civic.gid.obo | civic.gid OBO | civic.gid.obo (44.6 KB) | Product | obo | had primary source | civic.gid OBO |
| obo-db-ingest.civic.gid.owl | civic.gid OWL | civic.gid.owl (57.5 KB) | Product | owl | had primary source | civic.gid OWL |
| obo-db-ingest.civic.gid.json | civic.gid OBO Graph JSON | civic.gid.json (54.5 KB) | Product | json | had primary source | civic.gid OBO Graph JSON |
| obo-db-ingest.civic.gid.sssom.tsv | civic.gid SSSOM | civic.gid.sssom.tsv (3.9 KB) | Mapping | sssom | had primary source | civic.gid SSSOM |
| service-kp.trapi | Service Provider TRAPI | Service%20Provider | Programming Interface | http | had primary source | TRAPI endpoint for the Service Provid... |
| myvariant.api | MyVariant.info API | query | Programming Interface | http | had primary source | MyVariant.info REST API (v1) for vari... |
Created: May 29, 2025 | Last modified: September 23, 2026