Evaluation for clinicalkg

Evaluator: Not specified

Evaluated on: 2025-08-26

This is a manual evaluation intended to identify potential barriers to reuse.


Access Level and Types

QuestionAnswerComment
Access to data outside of the knowledge graphN
API or online access to the knowledge graphYBoth
Multiple access options availableYNeo4j, docker, csv, python library
Source code availabilityYWell documented github https://github.com/MannLabs/CKG?tab=readme-ov-file
Downloadable knowledge graphYMany different ways

Section Score: 4/5

Provenance of Nodes and Edges

QuestionAnswerComment
Source list providedYIn github with links as well as supplemental table S1
Source versions informationN
Import dependenciesYIn github and documents on how to download and use
Node and edge sourcesYEdges have pubmed identifiers
Edges deduplicationYBuilt in redundancy to assess overlap and disagreememnt of sources
Triples source detailsN
Edge type schemaN

Section Score: 4/7

Documented standards, schema, construction

QuestionAnswerComment
Biological usable dataYUse all external identifiers; ontolgies
Resolvable IDsYUsed standardized identifiers for nodes not described with exsiting terminoloies or ontologies
Construction documentationYWell documented in the paper and a github is well done
Transformation documentationN
Schema usedYCustom; defined in paper figure 3A

Section Score: 4/5

Update frequency and versioning

QuestionAnswerComment
Stable versionsYThree versions
Public tracker informationYEncouraged through github
Knowledge graph contact informationYMann labs
Updated annuallyYNewest is from 2022
Prior versions accessY

Section Score: 5/5

Evaluation - Metrics and Fitness for Purpose

QuestionAnswerComment
Use case providedYNon-alcoholic fatty liver disease; cancer biomarkers; identify theraputic options for chemorefractory cases
Evaluation against other modelsYCompared their ability to identify cancer biomarkers with paper from 2018
Defined scopeYHarmonization of proteomics with other omics data
Multiple evaluation methodsN
Accuracy metricsN

Section Score: 3/5

License Information

QuestionAnswerComment
LicenseC BY-NC 4.0