is a Data Source.
CollecTRI is a comprehensive collection of signed transcription factor (TF)-target gene regulatory interactions compiled from 12 different resources. It provides high-confidence regulons with expanded TF coverage and the sign (activation or repression) of each interaction, enabling accurate estimation of transcription factor activities from gene expression data. The regulons are distributed through the decoupler ecosystem and OmniPath for downstream enrichment and footprint analysis.
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| collectri.regulons | CollecTRI Regulons | CollecTRI | MappingProduct | csv | The CollecTRI gene regulatory network... |
| collectri.decoupler | CollecTRI via decoupler | decoupler-py.readthedocs.io | ProcessProduct | python | Programmatic access to the CollecTRI ... |
| collectri.docs | CollecTRI Repository and Documentation | CollecTRI | DocumentationProduct | http | Source code, construction scripts, be... |
| ID | Name | URL | Category | Format | Relation | Description |
|---|---|---|---|---|---|---|
| biobtree.api | BioBTree REST API | api | ProgrammingInterface | http | had primary source | REST API for searching identifiers an... |
CollecTRI is a gene regulatory network resource that provides signed transcription factor (TF)-target gene interactions compiled from 12 different resources. Each interaction carries a sign indicating whether the TF activates or represses its target, and the combined collection expands transcription factor coverage relative to prior individual resources.
The regulons are designed for accurate estimation of transcription factor activities from gene expression data and are accessible programmatically through the decoupler Python package and the OmniPath database. The repository additionally provides the scripts used to construct the network along with benchmarking and case-study analyses.
Created: June 15, 2026 | Last modified: June 15, 2026