cpic

is a General purpose Resource.

The Clinical Pharmacogenetics Implementation Consortium (CPIC) creates, curates, and disseminates freely available, peer-reviewed, evidence-based, and updatable clinical practice guidelines that translate patient pharmacogenetic test results into actionable prescribing decisions. CPIC also publishes structured gene-drug annotations, allele function data, standardized terminology resources, and implementation tools (database, API, SOPs, educational materials). Since 2025-07-30 CPIC content is hosted within ClinPGx (registry id clinpgx) and cpicpgx.org pages redirect there; the CPIC name and guidelines continue under ClinPGx.

License

CC0 1.0

Homepage

cpic

Repository

GitHub

Infores ID

Unknown

FAIRsharing ID

Unknown

Product Summary

Products

From this Resource
ID Name URL Category Format Description
cpic.portal CPIC Website Portal cpic GraphicalInterface http Main CPIC website portal providing ac...
cpic.guidelines CPIC Clinical Practice Guidelines guidelines DocumentationProduct http Peer-reviewed, evidence-based, updata...
cpic.genes_drugs CPIC Genes-Drugs Tables pairs Product http Curated gene–drug pair tables linking...
cpic.alleles CPIC Allele & Diplotype Function Tables cpicResources#guideline-alleles Product http Allele function and diplotype-to-phen...
cpic.api CPIC Database & API cpicResources#database-and-api ProgrammingInterface json Structured data (database and API) fo...
cpic.sop CPIC Pharmacogene Curation SOP CPIC%20Pharmacogene%20Curation%20SOP.pdf (793.7 KB) DocumentationProduct pdf Standard operating procedure PDF for ...
cpic.overview.slides CPIC Overview Presentation Slides CPIC-overview-updates-02.2025.pptx (8.2 MB) DocumentationProduct http Overview slide deck describing CPIC a...
cpic.onepager CPIC One-Page Summary CPIC-One-Page-CLEAN.docx (156.4 KB) DocumentationProduct docx One-page summary document providing c...
cpic.term_standardization CPIC Term Standardization Project cpicTermStandardization DocumentationProduct http Term standardization project resource...
cpic.cyp2d6_translation CPIC CYP2D6 Genotype to Phenotype Project cpicCyp2d6Standardization DocumentationProduct http CYP2D6 genotype to phenotype translat...
From other Resources
ID Name URL Category Format Relation Description
epigraphdb.graph EpiGraphDB Graph Database graph-database GraphProduct neo4j had primary source Integrated graph knowledge base combi...
clinpgx.portal ClinPGx Portal www.clinpgx.org GraphicalInterface was derived from ClinPGx web portal for browsing genes...

Details

Overview

Since 2025-07-30 CPIC is delivered through ClinPGx, which unifies PharmGKB, CPIC and PharmCAT. The standalone cpicpgx.org site redirects into the CPIC section of ClinPGx and is stated to be retiring. Product URLs on this page were repointed to their ClinPGx targets on 2026-09-02, following the redirects the CPIC site issues. Three files remain on CPIC hosts with no redirect and no known ClinPGx copy: the API at api.cpicpgx.org, the overview slides on files.cpicpgx.org and the one-pager under cpicpgx.org/wp-content. They answered normally on 2026-09-02 and will need repointing when those hosts retire.

The Clinical Pharmacogenetics Implementation Consortium (CPIC) facilitates the integration of pharmacogenetic test results into routine clinical care. CPIC develops and maintains evidence-based guidelines that translate patient genotype (or predicted phenotype) into prescribing recommendations, removing implementation barriers and standardizing clinical decision support for pharmacogenomics (PGx).

Key Components

  • Peer-reviewed clinical practice guidelines with standardized evidence grading
  • Genes–drugs, alleles, and diplotype function tables
  • Structured database and API for programmatic access to curated PGx relationships
  • Standard operating procedures and terminology standardization initiatives
  • Educational materials: overview slides, one-pager, videos, and implementation resources
  • Community engagement via announcements, working groups, and discussion lists

Licensing

CPIC resources are freely available under a Creative Commons public domain license (see licensing page). Users must ensure clinical application is accompanied by professional review; resources are not a substitute for medical judgment.

Citation (example guideline reference format)

Caudle KE, Klein TE, Whirl-Carrillo M, et al. (CPIC® guideline citation – see specific guideline publication). Clinical Pharmacology & Therapeutics. (Refer to https://cpicpgx.org/publications/ for full list.)

Contact

General inquiries: contact@cpicpgx.org (not re-verified since the ClinPGx move; feedback@clinpgx.org is the ClinPGx address). Additional forms and subscription options are available on the ClinPGx CPIC contact section for allele function questions, announcements, and discussion list enrollment.

Is this information incorrect or incomplete? Request an update.

Created: September 03, 2025 | Last modified: September 02, 2026