dgidb

is a Data Source.

The Drug Gene Interaction Database (DGIdb) is a resource that consolidates disparate data sources describing drug-gene interactions and gene druggability to help researchers identify actionable drug targets or repurposable drugs for genes of interest.

Domains

health, pharmacology, drug discovery, genomics, precision medicine

License

MIT

Homepage

dgidb

Repository

GitHub

Infores ID

infores:dgidb

FAIRsharing ID

Unknown

Product Summary

Products

From this Resource
ID Name URL Category Format Description
dgidb.api DGIdb API api ProgrammingInterface ❔ API for programmatically accessing th...
From other Resources
ID Name URL Category Format Description
rtx-kg2.graph.nodes RTX-KG2.10.1c KGX JSONL Nodes kg2c-2.10.1-v1.0-nodes.jsonl.gz (359.1 MB) GraphProduct kgx-jsonl Nodes for KGX distribution of the RTX...
rtx-kg2.graph.edges RTX-KG2.10.1c KGX JSONL Edges kg2c-2.10.1-v1.0-edges.jsonl.gz (1.7 GB) GraphProduct kgx-jsonl Edges for KGX distribution of the RTX...
rtx-kg2.neo4j RTX-KG2 Neo4j arax.ncats.io ProgrammingInterface ❔ Neo4j distribution of the RTX-KG2 as ...
clinicalkg.graph CKG Graph Dump 1 GraphProduct mixed Neo4j database dump of the Clinical K...
cancer-genome-interpreter.clinicalkg.graph CKG Graph Dump 1 GraphProduct mixed Neo4j database dump of the Clinical K...
translator.dgidb.graph Translator DGIdb KGX Graph latest GraphProduct kgx-jsonl KGX JSONL graph package for DGIdb dis...
translator.translator_kg.graph Translator Aggregate KGX Graph latest GraphProduct kgx-jsonl Aggregated KGX JSONL graph package co...
ckg.graph CKG Graph Database Dump 1 GraphProduct neo4j Graph database dump and additional re...

Details

DGIdb: Drug Gene Interaction Database

The Drug Gene Interaction Database (DGIdb) is a web resource that consolidates disparate data sources describing drug-gene interactions and gene druggability information. DGIdb helps researchers to prioritize the investigation of drug-gene interactions and identify actionable drug targets or repurposable drugs for genes of interest.

Key Features

  • Comprehensive Integration: Combines data from multiple sources of drug-gene interactions and druggable gene categories
  • Advanced Search: Search for drug-gene interactions involving genes or drugs of interest
  • Druggable Gene Categories: Browse druggable gene categories to identify genes that are potentially druggable
  • API Access: Programmatically access DGIdb data through a JSON-based API
  • Regular Updates: Continually updated with new drug-gene interaction sources

Applications

DGIdb can be used to:

  • Identify potential drug targets among a set of genes
  • Find existing drugs that might interact with genes of interest
  • Identify druggable genes within disease-specific gene sets
  • Prioritize genes for experimental follow-up
  • Support precision medicine initiatives by connecting genomic data to potential therapeutic options

Data Sources

DGIdb integrates data from various sources including:

  • Drug databases
  • Gene interaction databases
  • Clinical trial repositories
  • Pharmaceutical knowledge bases
  • Literature mining resources

This integration provides researchers with a comprehensive resource for drug-gene interaction information to support drug discovery and repurposing efforts in genomic medicine.

Is this information incorrect or incomplete? Request an update.

Created: May 30, 2025 | Last modified: January 23, 2026