erccreg

is a Data Source.

ERCC Regulatory Element dataset (erccreg) is a collection of data related to regulatory elements of extracellular RNA as part of the NIH Common Fund's Extracellular RNA Communication Consortium (ERCC) program. This dataset focuses on RNA-based regulatory mechanisms involved in extracellular communication.

Domains

biomedical, genomics, chemistry and biochemistry

License

CC BY 4.0

Homepage

erccreg

Repository

Unknown

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Details

ERCC Regulatory Element Dataset

The ERCC Regulatory Element Dataset (erccreg) is part of the research output from the NIH Common Fund’s Extracellular RNA Communication Consortium (ERCC), which explores the biology and function of extracellular RNA (exRNA).

Overview

Extracellular RNA was once thought to exist in a stable form only inside cells, where it served as an intermediate in the translation from genes to proteins. However, research has revealed that RNAs can play a role in a variety of complex cellular functions, including cell-to-cell communication. The ERCC Regulatory Element Dataset focuses on the regulatory elements and mechanisms associated with exRNA function.

Research Context

This dataset is part of the broader ERCC initiative which aims to:

  1. Discover fundamental biological principles about the mechanisms of exRNA generation, secretion, and transport
  2. Identify and develop a catalog of exRNA found in normal human body fluids
  3. Investigate the potential for using exRNAs in the clinic as therapeutic molecules or biomarkers of disease

Data Access

The ERCC Regulatory Element dataset is referenced by other resources in the knowledge graph registry, but access to the primary data may be restricted. Interested researchers should contact the ERCC directly via the exRNA portal for information on data availability and access procedures.

For more information about exRNA research and related datasets, you can visit:

The exRNA Atlas contains small RNA sequencing and qPCR-derived exRNA profiles from human and mouse biofluids, processed using standardized pipelines and quality metrics.

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Created: June 04, 2025 | Last modified: October 15, 2025