glyconnect

is a Data Source.

GlyConnect is a knowledgebase of glycoproteins spanning protein, glycosite and glycan information, with data on various species, tissues, and disease associations.

Domains

biological systems, chemistry and biochemistry

License

CC-BY-4.0

Homepage

glyconnect

Repository

Unknown

Infores ID

Unknown

FAIRsharing ID

Unknown

Product Summary

Products

From this Resource
ID Name URL Category Format Description
glyconnect.site GlyConnect Web Interface glyconnect.expasy.org GraphicalInterface Web interface for exploring GlyConnec...
glyconnect.api.rest GlyConnect RESTful API api ProgrammingInterface RESTful API for accessing GlyConnect ...
glyconnect.api.sparql GlyConnect SPARQL Endpoint rdf ProgrammingInterface SPARQL endpoint for querying GlyConne...
glyconnect.compositions GlyConnect Glycan Compositions compositions Product csv Compositions dataset containing glyca...
glyconnect.immunoglobulins GlyConnect Immunoglobulins Dataset Immunoglobulins Product csv Immunoglobulins dataset containing gl...

Details

GlyConnect is a comprehensive knowledgebase of glycoproteomics data maintained by the SIB Swiss Institute of Bioinformatics. It integrates information spanning three key levels of glycobiology: proteins, glycosites (the specific locations where glycans attach to proteins), and glycan structures.

The database provides curated glycoproteomic data from various species, tissues, and disease states, with a particular focus on human glycoproteins. GlyConnect uses the Symbol Nomenclature for Glycans (SNFG) standard for representing glycan structures in a visually consistent way.

Key features of GlyConnect include:

  • Integration of glycoprotein data across multiple species
  • Mapping of glycan structures to specific attachment sites on proteins
  • Association of glycan profiles with diseases and tissues
  • Specialized datasets for important glycoprotein families (e.g., immunoglobulins)
  • Human milk oligosaccharide (HMO) data
  • COVID-19 related glycosylation data
  • O-linked monosaccharide information

GlyConnect serves as a valuable resource for researchers in glycobiology, proteomics, and biomedical sciences by providing a unified view of the complex relationships between proteins and their glycosylation patterns. The database is regularly updated and expanded to include new glycoproteomic data.

Access to GlyConnect is provided through a user-friendly web interface, programmatic access via RESTful and SPARQL APIs, and bulk downloads of specialized datasets.

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Created: May 07, 2025 | Last modified: December 07, 2025