is a Data Source.
GPCRdb is an information system for G protein-coupled receptors (GPCRs) that provides reference sequences and alignments with generic residue numbering, manually annotated experimental structures and state-specific structure models, ligands and bioactivities, receptor mutations, drugs and targets, signaling protein data, and web tools for structure, sequence and ligand analysis. It was started in 1993 and has been maintained by the David Gloriam group at the University of Copenhagen since 2013. Data are available through the web portal and a REST API under CC BY 4.0, and the source code is released under the Apache 2.0 license.
| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| gpcrdb.portal | GPCRdb Web Portal | gpcrdb.org | Graphical Interface | http | GPCRdb web portal for browsing and an... |
| gpcrdb.api | GPCRdb REST API | reference | Programming Interface | http | REST API returning JSON for most GPCR... |
| gpcrdb.data ⚠ | GPCRdb Reference Data Repository | gpcrdb_data | Product | mixed | GitHub repository collecting the refe... |
| gpcrdb.code | Protwis Source Code | protwis | Process | http | Protwis, the Django-based source code... |
| gpcrdb.docs | GPCRdb Documentation | docs.gpcrdb.org | Documentation | http | GPCRdb documentation covering recepto... |
GPCRdb is a reference resource for G protein-coupled receptors, the largest family of drug targets. It was started in 1993 by Gert Vriend, Ad IJzerman, Bob Bywater and Friedrich Rippmann, and stewardship moved to the David Gloriam group at the University of Copenhagen in 2013.
Data can be browsed on the web portal or retrieved as JSON from the REST API (see the API reference). The reference data used to build the database are kept in the gpcrdb_data repository, and the full source code is in protwis.
Per the GPCRdb legal notice, data are available under the Creative Commons Attribution 4.0 International license and the source code under the Apache 2.0 license.
Created: October 04, 2026 | Last modified: October 04, 2026