gtrx

is an Aggregator.

Genome-to-Treatment (GTRx) is a NCATS Translator knowledge provider exposed through a BioThings API. It contains recommended acute treatments and interventions for seriously ill newborns, infants, and children with newly diagnosed genetic diseases, including therapeutics, dietary changes, surgery, medical devices, and other interventions.

Compare
Domains

genomics, pharmacology, precision medicine, biomedical

License

Warning: No license entered

Homepage

gtrx

Repository

GitHub

Infores ID

infores:gtrx

FAIRsharing ID

Unknown

Product Summary

Products

From this Resource
ID Name URL Category Format Description
gtrx.api gTRx API gtrx ProgrammingInterface json BioThings API for querying Genome-to-...
gtrx.data ⚠ gTRx Data metadata Product mixed BioThings GTRx association collection...

Details

Genome-to-Treatment

Overview

Genome-to-Treatment (GTRx) is a NCATS Translator knowledge provider exposed through the BioThings API framework. It provides association records for acute management guidance in genetic diseases, including drugs, dietary changes, procedures, medical devices, and other interventions.

Key Features

  • Genomic-Drug Connections: Links genetic variants to drug responses and treatment options
  • Precision Medicine Focus: Supports personalized treatment recommendations based on genomic profiles
  • Multi-Source Integration: Aggregates data from genomic databases, pharmacological resources, and clinical studies
  • Translator Integration: Registered in the Translator ecosystem as infores:gtrx and exposed as the BioThings GTRx API
  • Evidence-Based: Curates relationships with supporting evidence from literature and clinical data

Use Cases

  • Identifying potential drug treatments based on genomic alterations
  • Exploring pharmacogenomic relationships
  • Supporting clinical decision-making in precision oncology and other therapeutic areas
  • Discovering drug repurposing opportunities based on genetic mechanisms

Products

gTRx API

BioThings API endpoint providing programmatic access to Genome-to-Treatment association records for integration into Translator workflows.

gTRx Data

Integrated BioThings association records connecting genetic diseases with acute management interventions.

Information Resource ID

This resource has the Information Resource identifier: infores:gtrx

Domains

  • Genomics
  • Pharmacology
  • Precision Medicine
  • Translational
  • Biomedical

Tags

  • NCATS Translator

Is this information incorrect or incomplete? Request an update.

Created: November 05, 2025 | Last modified: June 02, 2026