homologene

is a Data Source.

HomoloGene was NCBI's database of homologs (genes with common ancestry) from completely sequenced eukaryotic genomes. The database organized genes into homology groups representing putative orthologs and paralogs across multiple species. HomoloGene was retired in January 2024 and replaced by the NCBI Orthologs dataset, which is now accessible through NCBI Datasets and the Gene database. The last HomoloGene build (build 68) was produced in 2014 and is no longer aligned with current data in NCBI RefSeq and Gene. Historical data from build 68 remains available on FTP for archival purposes only.

Domains

biological systems, genomics

License

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Homepage

homologene

Repository

Unknown

Infores ID

infores:homologene

FAIRsharing ID

Unknown

Products

From this Resource
ID Name URL Category Format Description
homologene.data HomoloGene Data File (Build 68 - Archive) homologene.data (13.2 MB) Product tsv Tab-delimited file containing HomoloG...
homologene.xml HomoloGene XML Data (Build 68 - Archive) homologene.xml.gz (167.7 MB) Product xml XML dump of the HomoloGene build 68 c...
homologene.ftp_archive HomoloGene FTP Archive HomoloGene DocumentationProduct http Complete FTP archive of all HomoloGen...

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Created: November 04, 2025 | Last modified: November 04, 2025