is an Aggregator.
The Human Protein Atlas (HPA) is a Swedish-based program aiming to map all human proteins in cells, tissues and organs using an integration of various omics technologies, including antibody-based imaging, mass spectrometry-based proteomics, transcriptomics and systems biology. The HPA aggregates and presents data from nine different resources covering tissue, brain, single cell, subcellular, cancer, blood, cell line, structure, and interaction atlases.
biomedical, proteomics, genomics, anatomy and development, health
infores:hpa
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| hpa.portal | Human Protein Atlas Portal | www.proteinatlas.org | GraphicalInterface | http | Main web portal for exploring protein... |
| hpa.proteinatlas.tsv | HPA Complete Data (TSV) | proteinatlas.tsv.zip (6.0 MB) | Product | tsv | Complete Human Protein Atlas data in ... |
| hpa.proteinatlas.json | HPA Complete Data (JSON) | proteinatlas.json.gz (10.3 MB) | Product | json | Complete Human Protein Atlas data in ... |
| hpa.proteinatlas.xml | HPA Complete Data (XML) | proteinatlas.xml.gz (679.1 MB) | Product | xml | Complete Human Protein Atlas data in ... |
| hpa.normal_tissue | HPA Normal Tissue Data | data | Product | tsv | Tissue atlas immunohistochemistry exp... |
| hpa.pathology | HPA Pathology Data | data | Product | tsv | Cancer atlas pathology and prognostic... |
| hpa.subcellular_location | HPA Subcellular Location Data | data#locations | Product | tsv | Subcellular atlas localization data f... |
| hpa.rna_tissue | HPA RNA Tissue Expression Data | data | Product | tsv | Tissue atlas transcript expression da... |
| hpa.rna_celline | HPA RNA Cell Line Expression Data | data | Product | tsv | Cell line atlas RNA expression data s... |
| hpa.rna_single_cell | HPA Single Cell RNA Expression Data | data | Product | tsv | Single Cell Type atlas data covering ... |
| hpa.brain_rna | HPA Brain RNA Expression Data | data | Product | tsv | Brain atlas transcript expression dat... |
| hpa.blood_protein | HPA Blood Protein Data | data#blood_conc | Product | tsv | Blood atlas protein concentration dat... |
| hpa.rna_immune_cell | HPA Immune Cell RNA Data | data#immune_cells_hpa | Product | tsv | Immune cell atlas transcript expressi... |
| hpa.api.xml | HPA XML API | download | ProgrammingInterface | xml | Programmatic access to individual pro... |
| hpa.api.tsv | HPA TSV API | download | ProgrammingInterface | tsv | Programmatic access to individual pro... |
| hpa.api.json | HPA JSON API | download | ProgrammingInterface | json | Programmatic access to individual pro... |
| hpa.api.rdf | HPA RDF API | download | ProgrammingInterface | rdfxml | Programmatic access to individual pro... |
| ID | Name | URL | Category | Format | Relation | Description |
|---|---|---|---|---|---|---|
| bioteque.embeddings | Bioteque Embeddings | embeddings | Product | ❔ | had primary source | Network embeddings of the Bioteque gr... |
| clinicalkg.graph | CKG Graph Dump | 1 | GraphProduct | mixed | had primary source | Neo4j database dump of the Clinical K... |
| cancer-genome-interpreter.clinicalkg.graph | CKG Graph Dump | 1 | GraphProduct | mixed | had primary source | Neo4j database dump of the Clinical K... |
| spoke.graph | SPOKE Graph | ❔ | GraphProduct | ❔ | had primary source | The SPOKE knowledge graph containing ... |
| pheknowlator.graph | PheKnowLator graph | knowledge_graphs?pageState=(%22StorageObjectListTable%22:(%22f%22:%22%255B%255D%22))&inv=1&invt=Ab5_1Q&project=pheknowlator | GraphProduct | owl | had primary source | PheKnowLator graph files, including s... |
| unibiomap.links | UniBioMap Graph Links | unibiomap.links.csv (1.3 GB) | GraphProduct | csv | had primary source | Core UniBioMap graph edges file. |
| unibiomap.auxs | UniBioMap Graph Auxiliaries | unibiomap.auxs.tsv (563.9 MB) | GraphProduct | tsv | had primary source | Auxiliary UniBioMap graph annotations... |
| unibiomap.pred | UniBioMap Predicted Graph | unibiomap.pred.csv (2.3 GB) | GraphProduct | csv | had primary source | Predicted UniBioMap graph edges with ... |
| unibiomap.pred.full | UniBioMap Predicted Graph (Full) | unibiomap.pred.full.csv (5.9 GB) | GraphProduct | csv | had primary source | Full unfiltered UniBioMap predicted g... |
| ckg.graph | CKG Graph Database Dump | 1 | GraphProduct | neo4j | had primary source | Graph database dump and additional re... |
The Human Protein Atlas (HPA) is a comprehensive Swedish-based program that aims to map all human proteins in cells, tissues, and organs using integration of various omics technologies. As one of the world’s largest proteomics initiatives, HPA aggregates and presents data from multiple sources to create a comprehensive resource for understanding human protein expression and localization.
The Human Protein Atlas integrates antibody-based imaging, mass spectrometry-based proteomics, transcriptomics, and systems biology to provide a comprehensive view of the human proteome. The resource is organized into nine interconnected atlases, each focusing on different aspects of protein biology.
Protein and RNA expression profiles in normal human tissues based on antibodies and transcriptomics, covering:
Detailed protein and spatial RNA expression profiles in the human brain:
Comprehensive single-cell RNA expression profiles across tissues:
Spatial subcellular protein localization in human cells:
Protein and RNA profiles in human cancers:
Blood protein levels in health and disease:
RNA expression profiles in human cell lines:
3D structures of human proteins with antibody-binding sites and genetic variants:
Human protein-protein interactions including 3D structures and metabolic enzyme profiles:
The Human Protein Atlas serves multiple research communities:
Interactive exploration of protein expression data with advanced search and filtering capabilities.
Complete datasets available in multiple formats for computational analysis and integration.
RESTful APIs for automated data retrieval using Ensembl gene identifiers.
Data integrated into major biological databases and analysis platforms.
All Human Protein Atlas data is freely available under the Creative Commons Attribution-ShareAlike 3.0 International License. Users are encouraged to cite the appropriate HPA publications when using the data in research.
Created: October 09, 2025 | Last modified: May 23, 2026