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The Human Protein Reference Database (HPRD) was a comprehensive, manually curated collection of information on human proteins, including protein-protein interactions, post-translational modifications (PTMs), enzyme-substrate relationships, subcellular localization, tissue expression, and disease associations. Developed through collaboration between the Institute of Bioinformatics in Bangalore, India and Johns Hopkins University in Baltimore, USA, HPRD contained over 20,000 protein entries with more than 36,500 unique protein-protein interactions and 18,000 PTMs before being discontinued. The database served as a major resource for the human proteome from 2003 to approximately 2010.
biomedical, proteomics, biological systems, systems biology
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| hprd.ppi.data ⚠ | HPRD Protein-Protein Interactions | www.hprd.org | Product | psi_mi_mitab | HPRD protein-protein interaction data... |
| hprd.xml.download ⚠ | HPRD XML Data Download | www.hprd.org | DocumentationProduct | ❔ | HPRD data in XML format for programma... |
| hprd.tsv.download ⚠ | HPRD Tab-Delimited Data Download | www.hprd.org | DocumentationProduct | ❔ | HPRD data in tab-delimited format for... |
| hprd.phosphomotif.finder ⚠ | HPRD PhosphoMotif Finder | www.hprd.org | GraphicalInterface | http | PhosphoMotif Finder tool for identify... |
| hprd.genprot.viewer ⚠ | GenProt Viewer | www.genprot.org | GraphicalInterface | http | GenProt Viewer for integrated genomic... |
| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| irefindex.database | iRefIndex Database | ❔ | Product | psi_mi_mitab | Historical consolidated protein inter... |
Created: October 30, 2025 | Last modified: October 31, 2025