intact

is an Aggregator.

It is part of the BER collection.

IntAct is an open, curated molecular interaction database maintained at EMBL‑EBI. It aggregates experimentally-derived interaction evidence from literature curation and direct submissions, and distributes data in PSI‑MI XML and MITAB formats along with curated datasets and documentation.

Domains

proteomics, systems biology

License

CC BY 4.0

Homepage

intact

Repository

GitHub

Infores ID

infores:intact

FAIRsharing ID

Unknown

Product Summary

Products

From this Resource
ID Name URL Category Format Description
intact.portal IntAct Portal home GraphicalInterface http Web portal for browsing, searching, a...
intact.api IntAct Web Service ws ProgrammingInterface http IntAct web service and URL-based prog...
intact.ftp.psi25 IntAct PSI-MI XML 2.5 psi25 Product psi_mi_xml IntAct data in PSI-MI XML 2.5 format ...
intact.ftp.psi30 IntAct PSI-MI XML 3.0 psi30 Product psi_mi_xml IntAct data in PSI-MI XML 3.0 format ...
intact.ftp.psimitab IntAct PSI-MI MITAB 2.7 psimitab Product psi_mi_mitab IntAct data in PSI-MI MITAB format (d...
intact.ftp.psimitab.all IntAct MITAB Archive intact.zip (807.1 MB) Product psi_mi_mitab Entire MITAB export of the database a...
intact.datasets IntAct Datasets datasets Product http Curated and computational datasets (d...
intact.docs.user-guide IntAct User Guide user-guide DocumentationProduct http User guide and documentation for sear...
afcs.intact.mitab AFCS IntAct MITAB Dataset AFCS.zip (704.1 KB) Product psi_mi_mitab IntAct-hosted AFCS protein interactio...
From other Resources
ID Name URL Category Format Relation Description
bioteque.embeddings Bioteque Embeddings embeddings Product had primary source Network embeddings of the Bioteque gr...
clinicalkg.graph CKG Graph Dump 1 GraphProduct mixed had primary source Neo4j database dump of the Clinical K...
epigraphdb.graph EpiGraphDB Graph Database graph-database GraphProduct neo4j had primary source Integrated graph knowledge base combi...
rnacentral.portal RNAcentral Portal rnacentral.org GraphicalInterface http had primary source Web portal for searching and browsing...
rnacentral.api RNAcentral REST API api ProgrammingInterface http had primary source REST API for programmatic access to R...
rnacentral.ftp RNAcentral FTP Archive RNAcentral Product http had primary source FTP archive with current and archived...
rnacentral.public-db RNAcentral Public Postgres Database public-database DataModelProduct postgres had primary source Public PostgreSQL database for direct...
automat.intact intact_automat e5b936f966a02c2c GraphProduct kgx-jsonl had primary source IntAct Automat
cancer-genome-interpreter.clinicalkg.graph CKG Graph Dump 1 GraphProduct mixed had primary source Neo4j database dump of the Clinical K...
genecards.protein.interactions GeneCards Protein Interactions www.genecards.org Product http had primary source Protein interaction data aggregated f...
irefindex.database iRefIndex Database Product psi_mi_mitab had primary source Historical consolidated protein inter...
translator.intact.graph Translator IntAct KGX Graph latest GraphProduct kgx-jsonl had primary source KGX JSONL graph package for IntAct di...
unibiomap.links UniBioMap Graph Links unibiomap.links.csv (1.3 GB) GraphProduct csv had primary source Core UniBioMap graph edges file.
unibiomap.auxs UniBioMap Graph Auxiliaries unibiomap.auxs.tsv (563.9 MB) GraphProduct tsv had primary source Auxiliary UniBioMap graph annotations...
unibiomap.pred UniBioMap Predicted Graph unibiomap.pred.csv (2.3 GB) GraphProduct csv had primary source Predicted UniBioMap graph edges with ...
unibiomap.pred.full UniBioMap Predicted Graph (Full) unibiomap.pred.full.csv (5.9 GB) GraphProduct csv had primary source Full unfiltered UniBioMap predicted g...
string.protein.links STRING Protein Links protein.links.v12.0.txt.gz (128.7 GB) GraphProduct txt had primary source protein network data (full network, s...
string.protein.links.detailed STRING Protein Links Detailed protein.links.detailed.v12.0.txt.gz (189.6 GB) GraphProduct txt had primary source protein network data (full network, i...
string.protein.links.full STRING Protein Links Full protein.links.full.v12.0.txt.gz (199.6 GB) GraphProduct txt had primary source protein network data (full network, i...
string.protein.physical.links STRING Protein Physical Links protein.physical.links.v12.0.txt.gz (11.1 GB) GraphProduct txt had primary source protein network data (physical subnet...
string.protein.physical.links.detailed STRING Protein Physical Links Detailed protein.physical.links.detailed.v12.0.txt.gz (13.8 GB) GraphProduct txt had primary source protein network data (physical subnet...
string.protein.physical.links.full STRING Protein Physical Links Full protein.physical.links.full.v12.0.txt.gz (14.5 GB) GraphProduct txt had primary source protein network data (physical subnet...
string.cog.links STRING COG Links COG.links.v12.0.txt.gz (176.8 MB) GraphProduct txt had primary source association scores between orthologou...
string.cog.links.detailed STRING COG Links Detailed COG.links.detailed.v12.0.txt.gz (238.7 MB) GraphProduct txt had primary source association scores (incl. subscores p...
string.database STRING Database Network Schema network_schema.v12.0.sql.gz (262.2 GB) GraphProduct had primary source full database, part II: the networks ...
proteomehd.data ProteomeHD Data Data GraphProduct had primary source ProteomeHD data files
translator.translator_kg.graph Translator Aggregate KGX Graph latest GraphProduct kgx-jsonl had primary source Aggregated KGX JSONL graph package co...
ckg.graph CKG Graph Database Dump 1 GraphProduct neo4j had primary source Graph database dump and additional re...
imex.portal IMEx Portal www.imexconsortium.org GraphicalInterface http had primary source Search interface for the shared IMEx ...
imex.downloads IMEx Downloads downloads Product psi_mi_mitab had primary source IMEx interaction downloads distribute...

Details

IntAct

Overview

IntAct is a curated molecular interaction database, aggregating experimental evidence from the literature and direct submissions and distributing data in PSI‑MI XML and MITAB formats. It is part of the IMEx consortium and a Global Core Biodata Resource.

Access

  • Portal: browse and search interactions via the IntAct web interface
  • API: programmatic access through the IntAct web service and URL-based interface
  • FTP: bulk downloads in PSI‑MI XML (2.5, 3.0) and MITAB (2.7)
  • Datasets: curated and computational datasets with themed collections
  • Documentation: user guide covering data sources, formats, export, and submission

Citation

Please cite IntAct and any specific datasets used, and refer to the CC BY 4.0 license terms for data reuse.

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Created: July 08, 2025 | Last modified: May 04, 2026