inxight-drugs

is a Data Source.

Inxight Drugs is a comprehensive and curated drug database developed by the National Center for Advancing Translational Sciences (NCATS) to support translational research. It provides rigorously curated information on drug substances, including their regulatory approval and development status, ingredient definitions, mechanisms of action, biological targets, and pharmacological class. The resource resolves ambiguity in substance identity by applying the FDA Global Substance Registration System (GSRS) and links each substance to detailed marketing, regulatory, and clinical development metadata. Inxight Drugs serves as an upstream primary source for downstream knowledge resources such as the Molecular Data Provider (MolePro) and the Molecular Data Knowledge Provider.

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Domains

pharmacology, drug discovery, clinical, chemistry and biochemistry

License

Public Domain (NCATS states all facts in these datasets are in the public domain)

Homepage

inxight-drugs

Repository

Unknown

External IDs
  • Infores: infores:inxight-drugs

Product Summary

Products

From this Resource
ID Name URL Category Format Description
inxight-drugs.api Inxight: Drugs REST API substances (38.9 KB) Programming Interface http Public REST API providing programmati...
inxight-drugs.portal Inxight: Drugs Web Portal drugs.ncats.io Graphical Interface http Web portal interface for browsing and...
From other Resources
ID Name URL Category Format Relation Description
molepro.graph.nodes Nodes for Molecular Data KP nodes.tsv (3.4 GB) Graph kgx had primary source KGX nodes for Molecular Data KP
molepro.graph.edges Edges for Molecular Data KP edges.tsv (18.8 GB) Graph kgx had primary source KGX edges for Molecular Data KP
molepro.api MolePro API api Programming Interface http had primary source MolePro API providing access to the k...
molepro.trapi MolePro TRAPI Interface ui Programming Interface http had primary source TRAPI-compliant interface for MolePro...
molepro.catalog MolePro Knowledge Sources Catalog transformers (2.0 MB) Product json had primary source Catalog of MolePro knowledge sources ...

Details

Inxight: Drugs

Overview

Inxight: Drugs is a comprehensive and curated drug database developed by the National Center for Advancing Translational Sciences (NCATS). It is designed to support translational research by providing high-quality, manually curated information about drug substances and their development across the discovery-to-market pipeline.

Curated Content

The resource provides detailed information for each drug substance, including:

  • Substance identity: Rigorous ingredient definitions based on the FDA Global Substance Registration System (GSRS), resolving ambiguity in chemical and biological substance identity.
  • Approval and development status: Regulatory approval status and the stage of clinical or commercial development.
  • Mechanisms and targets: Mechanisms of action and associated biological targets.
  • Pharmacology and class: Pharmacological class and related drug metadata.
  • Marketing and regulatory metadata: Information on marketing status and regulatory history.

Role as an Upstream Source

Inxight: Drugs acts as an upstream primary source (transformer input) for downstream knowledge resources, including the Molecular Data Provider (MolePro) and the molecular-data knowledge provider, which transform and integrate its curated drug data into knowledge-graph form.

Access

  • Web portal: Browse and search the database at drugs.ncats.io.
  • REST API: Programmatic access is available through the public Inxight Drugs API.

Automated Evaluation

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Created: June 18, 2026 | Last modified: September 08, 2026