is an Aggregator.
It is part of the Translator collection.
MyVariant.info is a BioThings web service from the Su and Wu labs at Scripps Research that serves human genetic variant annotations aggregated from about 20 sources, including dbSNP, ClinVar, gnomAD, ExAC, dbNSFP, CADD, CIViC, COSMIC, DoCM, the Cancer Genome Interpreter, the GWAS Catalog and SnpEff predictions, through a fast query and annotation API keyed on HGVS identifiers. The build of 2025-06-24 held about 1.51 billion variant documents. It is one of the knowledge sources of the Translator Service Provider KP.
| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| myvariant.api | MyVariant.info API | query | Programming Interface | http | MyVariant.info REST API (v1) for vari... |
| myvariant.metadata | MyVariant.info Build Metadata | metadata | Product | json | JSON metadata for the current MyVaria... |
| myvariant.docs | MyVariant.info Documentation | latest | Documentation | http | MyVariant.info documentation, coverin... |
| myvariant.python | myvariant Python Client | myvariant | Product | python | myvariant, the Python client for the ... |
| myvariant.code | MyVariant.info Source Code | myvariant.info | Process | python | Source code for the MyVariant.info se... |
| ID | Name | URL | Category | Format | Relation | Description |
|---|---|---|---|---|---|---|
| service-kp.trapi | Service Provider TRAPI | Service%20Provider | Programming Interface | http | had primary source | TRAPI endpoint for the Service Provid... |
MyVariant.info is a BioThings API that merges human variant annotations from many sources into one JSON document per variant, keyed on its HGVS genomic id (for example chr7:g.140453134T>C). It supports full-text style queries, batch lookups by id or rsid, and both the hg19 and hg38 assemblies.
The 2025-06-24 build metadata lists these sources: dbSNP (156), ClinVar (2025-05), gnomAD (2.1.1), ExAC (0.3.1), dbNSFP (4.8a), CADD, CIViC, COSMIC (68), DoCM, the Cancer Genome Interpreter, the GWAS Catalog, SnpEff (4.3k), the NHLBI Exome Variant Server, Geno2MP, EMVClass, GRASP, Wellderly, SNPedia and MutDB. Sources that have KG-Registry pages are cited on the API product. Each source keeps its own license (gnomAD and ExAC are ODbL, SNPedia is CC BY-NC-SA). The Apache-2.0 license on this page covers the service code only.
https://myvariant.info/v1/query and https://myvariant.info/v1/variant/<hgvs id>https://myvariant.info/v1/metadatapip install myvariantMyVariant.info is also exposed to the NCATS Biomedical Data Translator through the Service Provider KP’s TRAPI endpoint.
Created: October 04, 2026 | Last modified: October 05, 2026