is an Aggregator.
OpenPredict is an NCATS Translator Knowledge Provider that provides machine learning-based predictions for drug-target interactions and drug-disease associations to support drug repurposing. OpenPredict integrates multiple biomedical knowledge graphs and applies various machine learning algorithms to predict potential therapeutic uses for existing drugs. The service offers predictions with confidence scores and provides evidence trails linking drugs to diseases through intermediate biological entities like targets and pathways.
drug discovery, pharmacology, precision medicine, biomedical
infores:openpredict
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| openpredict.api | OpenPredict API | docs | ProgrammingInterface | http | TRAPI 1.4 API for predicted drug trea... |
| openpredict.ui | OpenPredict Swagger UI | docs | GraphicalInterface | http | Swagger UI documentation for interact... |
| openpredict.openapi | OpenPredict OpenAPI Specification | openapi.json (60.5 KB) | Product | json | OpenAPI JSON specification describing... |
| openpredict.predictions ⚠ | OpenPredict Prediction Data | docs | Product | mixed | Pre-computed prediction outputs expos... |
OpenPredict is an NCATS Translator Knowledge Provider that provides machine learning-based predictions for drug-target interactions and drug-disease associations to support drug repurposing.
Developed at the Institute for Data Science at Maastricht University, OpenPredict integrates multiple biomedical knowledge graphs and applies various machine learning algorithms to identify potential new therapeutic uses for existing drugs.
OpenPredict employs multiple algorithms including:
TRAPI-compliant RESTful API providing programmatic access to drug repurposing predictions, similar-entity queries, model metadata, and evidence/explanation endpoints.
Swagger UI documentation for exploring predictions, visualizing API examples, and accessing detailed operation schemas for drugs and diseases.
Pre-computed prediction results are exposed through the API operations rather than through a stable public bulk-download file.
This resource has the Information Resource identifier: infores:openpredict
Source code and documentation: https://github.com/MaastrichtU-IDS/translator-openpredict
Created: November 05, 2025 | Last modified: June 02, 2026