is a Data Source.
The Psychoactive Drug Screening Program (PDSP) at UNC Chapel Hill provides screening of novel psychoactive compounds for pharmacological and functional activity at cloned human or rodent CNS receptors, channels, and transporters. The PDSP Ki Database contains binding affinities for thousands of drugs and drug candidates at neuroreceptors, providing critical pharmacological data for drug discovery and neuroscience research.
pharmacology, neuroscience, drug discovery, biomedical
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| pdsp.web | PDSP Ki Database | kidb.php | GraphicalInterface | http | Web interface for searching and brows... |
| pdsp.data | PDSP Binding Data | kidb.php | Product | csv | Receptor binding affinity data for ps... |
| pdsp.protocols | PDSP Assay Protocols | PDSP%20Protocols%20II%202013-03-28.pdf (23.7 MB) | DocumentationProduct | Screening assay protocols and methodo... |
The Psychoactive Drug Screening Program (PDSP) at UNC Chapel Hill provides screening of novel psychoactive compounds for pharmacological and functional activity at cloned human or rodent CNS receptors, channels, and transporters.
Funded by the National Institute of Mental Health (NIMH), PDSP offers both screening services and a comprehensive database of receptor binding data (Ki values) for thousands of psychoactive drugs and drug candidates.
Searchable web database containing receptor binding affinities (Ki values) for psychoactive drugs and drug candidates across multiple neuroreceptor targets.
Downloadable datasets of receptor binding data for computational analysis and modeling.
Detailed protocols for PDSP’s standardized receptor binding and functional assays.
This resource has the Information Resource identifier: infores:pdsp
Created: November 05, 2025 | Last modified: November 05, 2025