is a Data Source.
The Psychoactive Drug Screening Program (PDSP) at UNC Chapel Hill provides screening of novel psychoactive compounds for pharmacological and functional activity at cloned human or rodent CNS receptors, channels, and transporters. The PDSP Ki Database contains binding affinities for thousands of drugs and drug candidates at neuroreceptors, providing critical pharmacological data for drug discovery and neuroscience research.
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| pdsp.web | PDSP Ki Database | kidb.php | Graphical Interface | http | Web interface for searching and brows... |
| pdsp.data | PDSP Binding Data | kiDownload | Product | csv | Downloadable PDSP Ki values with SMIL... |
| pdsp.data_mining | PDSP Ki Data Mining Tools | dataMining | Graphical Interface | http | PDSP Ki Database data-mining interfac... |
| pdsp.protocols | PDSP Assay Protocols | PDSP%20Protocols%20II%202013-03-28.pdf (23.7 MB) | Documentation | Screening assay protocols and methodo... | |
| ID | Name | URL | Category | Format | Relation | Description |
|---|---|---|---|---|---|---|
| stitch.portal | STITCH Web Portal | stitch-db.org | Product | http | had primary source | Web interface for searching and visua... |
| stitch.downloads | STITCH Data Downloads | download.pl | Product | tsv | had primary source | Downloadable data files containing ch... |
| stitch.api | STITCH API | access.pl?footer_active_subpage=apis | Programming Interface | http | had primary source | API for programmatic access to STITCH... |
| gpcrdb.data ⚠ | GPCRdb Reference Data Repository | gpcrdb_data | Product | mixed | had primary source | GitHub repository collecting the refe... |
The Psychoactive Drug Screening Program (PDSP) at UNC Chapel Hill provides screening of novel psychoactive compounds for pharmacological and functional activity at cloned human or rodent CNS receptors, channels, and transporters.
Funded by the National Institute of Mental Health (NIMH), PDSP offers both screening services and a comprehensive database of receptor binding data (Ki values) for thousands of psychoactive drugs and drug candidates.
Searchable web database containing receptor binding affinities (Ki values) for psychoactive drugs and drug candidates across multiple neuroreceptor targets.
Downloadable datasets of receptor binding data for computational analysis and modeling.
Detailed protocols for PDSP’s standardized receptor binding and functional assays.
This resource has the Information Resource identifier: infores:pdsp
Created: November 05, 2025 | Last modified: September 23, 2026