pharmacotherapydb

is a Data Source.

PharmacotherapyDB is a curated catalog of medical indications between small molecule compounds and complex human diseases. It was created as part of a network-based drug repurposing project and differentiates between disease-modifying (DM) and symptomatic (SYM) treatments, with each indication reviewed by multiple physicians. The initial release contains 97 diseases and 601 drugs, with 755 disease-modifying therapies, 390 symptomatic therapies, and 243 non-indications. The catalog uses standardized vocabularies (Disease Ontology and DrugBank) to facilitate data integration and adheres to pathophysiological principles.

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Repository

Unknown

Infores ID

infores:pharmacotherapydb

FAIRsharing ID

Unknown

⚠ The repository README states original PharmacotherapyDB content is CC0, but also notes upstream license constraints for integrated sources including DrugBank, MEDI, PREDICT, and EHRLink.

Product Summary

Publications

Systematic integration of biomedical knowledge prioritizes drugs for repurposing Preferred

Products

From this Resource

ID	Name	URL	Category	Format	Description
pharmacotherapydb.figshare	PharmacotherapyDB 1.0 Figshare Archive	m9.figshare.3103054	Product	http	Figshare archive for PharmacotherapyD...
pharmacotherapydb.indications	PharmacotherapyDB Indications TSV	indications.tsv (75.0 KB)	Product	tsv	Curated TSV catalog of drug-disease i...
pharmacotherapydb.catalog_xlsx	PharmacotherapyDB Catalog Workbook	catalog.xlsx (112.5 KB)	Product	http	Excel workbook for the Pharmacotherap...
pharmacotherapydb.diseases	PharmacotherapyDB Diseases TSV	diseases.tsv (1.6 KB)	Product	tsv	Disease table for the Pharmacotherapy...
pharmacotherapydb.drugs	PharmacotherapyDB Drugs TSV	drugs.tsv (6.0 KB)	Product	tsv	Drug table for the PharmacotherapyDB ...

From other Resources

ID	Name	URL	Category	Format	Relation	Description
alzkb.browser	AlzKB Graph Database Browser	login	GraphicalInterface	http	had primary source	A browser interface for a knowledge g...
alzkb.data	AlzKB Data Release (Version 2.0.0)	v2.0.0	GraphProduct	❔	had primary source	Memgraph data release for AlzKB.
ehrlink.pharmacotherapydb-processing	EHRLink PharmacotherapyDB Processing Files	ehrlink	Product	❔	was derived from	PharmacotherapyDB processing workspac...

Relevant Taxa

Human (NCBITaxon:9606)

Details

PharmacotherapyDB

PharmacotherapyDB is a curated catalog of medical indications between small molecule compounds and complex human diseases. Created as part of a network-based drug repurposing project, it differentiates between disease-modifying (DM) and symptomatic (SYM) treatments, with each indication reviewed by multiple physicians. The initial release contains 97 diseases, 601 drugs, 755 disease-modifying therapies, 390 symptomatic therapies, and 243 non-indications. The catalog uses standardized vocabularies (Disease Ontology and DrugBank) to facilitate data integration and is designed as a gold standard for computational drug repurposing approaches.