phenopacket-store

is a Data Source.

Phenopacket Store is a curated collection of GA4GH Phenopackets describing individuals with rare and Mendelian disease, assembled from the medical literature by the Monarch Initiative and GA4GH community. Each phenopacket captures a case's observed and excluded phenotypic features encoded with the Human Phenotype Ontology (HPO), along with the underlying genetic variants and disease diagnosis. The collection provides standardized, machine-readable case data used to power phenotype-driven analyses such as genotype-phenotype correlation studies and diagnostic tool benchmarking.

License

BSD-3-Clause

Repository

GitHub

Infores ID

infores:phenopacket-store

FAIRsharing ID

Unknown

Product Summary

Products

From this Resource
ID Name URL Category Format Description
phenopacket-store.release Phenopacket Store Release zenodo.13168726 Product json Versioned release of the Phenopacket ...
From other Resources
ID Name URL Category Format Relation Description
sri-reference-kg.graph SRI-Reference KG (KGX distribution) monarch-kg.tar.gz (219.4 MB) GraphProduct kgx had primary source KGX distribution of the SRI-Reference KG

Details

Phenopacket Store is a curated collection of GA4GH Phenopackets describing individuals with rare and Mendelian disease, assembled from the published medical literature by the Monarch Initiative and the broader GA4GH community. Each phenopacket records a case’s observed and excluded phenotypic features encoded with the Human Phenotype Ontology (HPO), together with the causal genetic variants and the disease diagnosis.

The collection provides standardized, machine-readable case data that power phenotype-driven analyses, including genotype-phenotype correlation studies and the benchmarking of phenotype-driven diagnostic tools. In KG-Registry, Phenopacket Store serves as an upstream ingest source for the Monarch/SRI Reference Knowledge Graph. Releases are versioned and archived on Zenodo.

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Created: June 18, 2026 | Last modified: June 27, 2026