is an Aggregator.
PhosphoSitePlus is a comprehensive resource for experimentally validated post-translational modifications (PTMs) with emphasis on phosphorylation, ubiquitination, acetylation, methylation and more. It aggregates curated site-specific modification data, kinase–substrate relationships, protein domains, mutation impact annotations, sequence motifs, and pathway/interaction context to support signaling, proteomics, and systems biology research.
proteomics, biomedical, biological systems
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| phosphositeplus.portal | PhosphoSitePlus Portal | www.phosphosite.org | GraphicalInterface | http | Web portal for browsing PTM sites, ki... |
| phosphositeplus.downloads | PhosphoSitePlus Downloads | staticDownloads | Product | http | Bulk data downloads (PTM site tables,... |
| phosphositeplus.about | PhosphoSitePlus About & Methods | staticAboutPhosphosite | DocumentationProduct | http | Methodology and curation overview inc... |
| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| clinicalkg.graph | CKG Graph Dump | 1 | GraphProduct | mixed | Neo4j database dump of the Clinical K... |
| cancer-genome-interpreter.clinicalkg.graph | CKG Graph Dump | 1 | GraphProduct | mixed | Neo4j database dump of the Clinical K... |
| kinace.portal | KinAce Web Portal | kinace.kinametrix.com | GraphicalInterface | http | Interactive web interface for explori... |
| unibiomap.links | UniBioMap Graph Links | unibiomap.links.csv (1.3 GB) | GraphProduct | csv | Core UniBioMap graph edges file. |
| unibiomap.auxs | UniBioMap Graph Auxiliaries | unibiomap.auxs.tsv (563.9 MB) | GraphProduct | tsv | Auxiliary UniBioMap graph annotations... |
| unibiomap.pred | UniBioMap Predicted Graph | unibiomap.pred.csv (2.3 GB) | GraphProduct | csv | Predicted UniBioMap graph edges with ... |
| unibiomap.pred.full | UniBioMap Predicted Graph (Full) | unibiomap.pred.full.csv (5.9 GB) | GraphProduct | csv | Full unfiltered UniBioMap predicted g... |
| ckg.graph | CKG Graph Database Dump | 1 | GraphProduct | neo4j | Graph database dump and additional re... |
PhosphoSitePlus aggregates high-quality experimentally validated post-translational modification (PTM) information, including phosphorylation, ubiquitination, acetylation, methylation, SUMOylation and others. Each modification site is annotated with residue position, surrounding sequence context, upstream enzymes (where known), literature references, and functional notes.
Please cite the latest PhosphoSitePlus update and foundational 2011 description paper when using the resource.
Created: August 12, 2025 | Last modified: September 11, 2025