is a Knowledge Graph.
It is part of the OKN collection.
The Protein Knowledge Network (ProKN) integrates protein-centric data with the genomic-centric datasets of the Common Fund Data Ecosystem (CFDE), spanning heterogeneous biological data types across multiple domains to foster CFDE re-use and collaboration through enhanced connectivity and data integration, enabling new capabilities for functional genomics and systems-level understanding of disease mechanisms.
proteomics, genomics, biomedical, systems biology
Warning: No license entered
Unknown
Unknown
Unknown
Github: chenchuming
| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| prokn.glygen.aminoacid.nodes | ProKN GlyGen AminoAcid Nodes | DDKG_PROTEOFORM.AminoAcid.nodes.csv (853 B) | GraphProduct | csv | GlyGen amino acid nodes used in ProKN |
| prokn.gtexexp.anatomy.nodes | ProKN GTEx Anatomy Nodes | DDKG_GTEXEXP.Anatomy.nodes.csv (6.8 KB) | GraphProduct | csv | GTEx expression anatomy nodes (GTEXEX... |
| prokn.hmaz.anatomy.nodes | ProKN HuBMAP Azimuth Anatomy Nodes | DDKG_HMAZ.Anatomy.nodes.csv (12.4 KB) | GraphProduct | csv | HuBMAP Azimuth anatomy nodes used in ... |
| prokn.imex.complex.nodes | ProKN IMEx Complex Nodes | IMEx.Complex.nodes.csv (1.3 MB) | GraphProduct | csv | IMEx complex nodes used in ProKN |
| prokn.idgp.compound.nodes | ProKN TCRD Compound-Protein Compound Nodes | DDKG_IDGP.Compound.nodes.csv (80.1 MB) | GraphProduct | csv | IDG/TCRD compound-protein nodes used ... |
| prokn.idgd.compound.nodes | ProKN TCRD Compound-Disease Compound Nodes | DDKG_IDGD.Compound.nodes.csv (103.3 KB) | GraphProduct | csv | IDG/TCRD compound-disease nodes used ... |
| prokn.hmaz.anatomy.has_marker_gene_in_heart.gene.edges | ProKN HuBMAP Azimuth Heart Marker Edges | DDKG_HMAZ.Anatomy.HAS_MARKER_GENE_IN_HEART.Gene.edges.csv (47.2 KB) | GraphProduct | csv | HuBMAP Azimuth anatomy to heart marke... |
| prokn.hmaz.anatomy.has_marker_gene_in_kidney.gene.edges | ProKN HuBMAP Azimuth Kidney Marker Edges | DDKG_HMAZ.Anatomy.HAS_MARKER_GENE_IN_KIDNEY.Gene.edges.csv (124.0 KB) | GraphProduct | csv | HuBMAP Azimuth anatomy to kidney mark... |
| prokn.hmaz.anatomy.has_marker_gene_in_liver.gene.edges | ProKN HuBMAP Azimuth Liver Marker Edges | DDKG_HMAZ.Anatomy.HAS_MARKER_GENE_IN_LIVER.Gene.edges.csv (55.4 KB) | GraphProduct | csv | HuBMAP Azimuth anatomy to liver marke... |
| prokn.idgp.compound.bioactivity.protein.edges | ProKN TCRD Compound-Protein Bioactivity Edges | DDKG_IDGP.Compound.BIOACTIVITY.Protein.edges.csv (122.2 MB) | GraphProduct | csv | TCRD compound bioactivity to protein ... |
| prokn.lincs.compound.in_similarity_relationship_with.compound.edges | ProKN LINCS Compound Similarity Edges | DDKG_LINCS.Compound.IN_SIMILARITY_RELATIONSHIP_WITH.Compound.edges.csv (5.9 MB) | GraphProduct | csv | LINCS compound similarity edges |
| prokn.idgd.compound.indication.diseaseorphenotype.edges | ProKN TCRD Compound-Disease Indication Edges | DDKG_IDGD.Compound.INDICATION.DiseaseOrPhenotype.edges.csv (1.6 MB) | GraphProduct | csv | TCRD compound indication edges to dis... |
| prokn.lincs.compound.negatively_regulates.gene.edges | ProKN LINCS Negative Regulation Edges | DDKG_LINCS.Compound.NEGATIVELY_REGULATES.Gene.edges.csv (27.0 MB) | GraphProduct | csv | LINCS compound negatively regulates g... |
| prokn.lincs.compound.positively_regulates.gene.edges | ProKN LINCS Positive Regulation Edges | DDKG_LINCS.Compound.POSITIVELY_REGULATES.Gene.edges.csv (26.9 MB) | GraphProduct | csv | LINCS compound positively regulates g... |
| prokn.pir.compound.skos_exact_match.compound.edges | ProKN PIR Compound Exact Match Edges | PIR.Compound.SKOS_EXACT_MATCH.Compound.edges.csv (95.5 MB) | GraphProduct | csv | PIR compound exact match edges |
| prokn.pir.gene.skos_exact_match.impchumangene.edges | ProKN PIR Gene Exact Match Edges | PIR.Gene.SKOS_EXACT_MATCH.ImpcHumanGene.edges.csv (4.6 MB) | GraphProduct | csv | PIR gene exact match to IMPC human ge... |
| prokn.interpro.domain.is_a.domain.edges | ProKN InterPro Domain Hierarchy Edges | InterPro.Domain.IS_A.Domain.edges.csv (167.0 KB) | GraphProduct | csv | InterPro domain is_a domain edges |
| prokn.hgnchpo.gene.associated_with.diseaseorphenotype.edges | ProKN HPO Gene-to-Phenotype Association Edges | DDKG_HGNCHPO.Gene.ASSOCIATED_WITH.DiseaseOrPhenotype.edges.csv (148.6 MB) | GraphProduct | csv | HPO gene-to-phenotype association edges |
| prokn.gtexexp.gene.expressed_in.anatomy.edges | ProKN GTEx Gene Expression Edges | DDKG_GTEXEXP.Gene.EXPRESSED_IN.Anatomy.edges.csv (325.3 MB) | GraphProduct | csv | GTEx gene expressed in anatomy edges |
| prokn.clinvar.gene.associated_with.diseaseorphenotype.edges | ProKN ClinVar Association Edges | DDKG_CLINVAR.Gene.GENE_ASSOCIATED_WITH_DISEASE_OR_PHENOTYPE.DiseaseOrPhenotype.edges.csv (16.1 MB) | GraphProduct | csv | ClinVar gene associated with disease/... |
| prokn.hgncuniprot.gene.is_protein.protein.edges | ProKN HGNC UniProt Gene-Protein Edges | DDKG_HGNCUNIPROT.Gene.IS_PROTEIN.Protein.edges.csv (1.7 MB) | GraphProduct | csv | HGNC to UniProt gene is_protein edges |
| prokn.pir.gene.skos_exact_match.impc_gene.edges | ProKN PIR Gene Exact Match Edges | PIR.Gene.SKOS_EXACT_MATCH.ImpcHumanGene.edges.csv (4.6 MB) | GraphProduct | csv | PIR gene exact match to IMPC human ge... |
| prokn.glygen.glycoprotein.glycosylated_at.glycosylationsite.edges | ProKN GlyGen Glycosylated Site Edges | DDKG_PROTEOFORM.Glycoprotein.GLYCOSYLATED_AT.GlycosylationSite.edges.csv (13.4 MB) | GraphProduct | csv | GlyGen glycoprotein glycosylated site... |
| prokn.glygen.glycoprotein.has_evidence.glycoproteinevidence.edges | ProKN GlyGen Evidence Edges | DDKG_PROTEOFORM.Glycoprotein.HAS_EVIDENCE.GlycoproteinEvidence.edges.csv (32.3 MB) | GraphProduct | csv | GlyGen glycoprotein evidence edges |
| prokn.glygen.glycoprotein.has_pro_entry.gpid2pro.edges | ProKN GlyGen PRO Entry Edges | DDKG_PROTEOFORM.Glycoprotein.HAS_PRO_ENTRY.GPID2PRO.edges.csv (14.8 MB) | GraphProduct | csv | GlyGen glycoprotein PRO entry edges |
| prokn.glygen.glycoprotein.sequence.isoform.edges | ProKN GlyGen Isoform Sequence Edges | DDKG_PROTEOFORM.Glycoprotein.SEQUENCE.Isoform.edges.csv (6.8 MB) | GraphProduct | csv | GlyGen glycoprotein isoform sequence ... |
| prokn.glygen.glycoprotein.sequence.protein.edges | ProKN GlyGen Protein Sequence Edges | DDKG_PROTEOFORM.Glycoprotein.SEQUENCE.Protein.edges.csv (7.4 MB) | GraphProduct | csv | GlyGen glycoprotein protein sequence ... |
| prokn.glygen.glycoproteinevidence.citation.glycoproteincitation.edges | ProKN GlyGen Evidence Citation Edges | DDKG_PROTEOFORM.GlycoproteinEvidence.CITATION.GlycoproteinCitation.edges.csv (558.3 KB) | GraphProduct | csv | GlyGen glycoprotein evidence citation... |
| prokn.glygen.glycosylation.has_enzyme_protein.protein.edges | ProKN GlyGen Enzyme Protein Edges | DDKG_GLYCANS.Glycosylation.HAS_ENZYME_PROTEIN.Protein.edges.csv (23.2 KB) | GraphProduct | csv | GlyGen glycosylation enzyme protein e... |
| prokn.glygen.glycosylationsite.has_saccharide.glytoucan.edges | ProKN GlyGen Saccharide Edges | DDKG_PROTEOFORM.GlycosylationSite.HAS_SACCHARIDE.Glytoucan.edges.csv (10.8 MB) | GraphProduct | csv | GlyGen glycosylation site saccharide ... |
| prokn.glygen.glycosylationsite.location.glygenlocation.edges | ProKN GlyGen Site Location Edges | DDKG_PROTEOFORM.GlycosylationSite.LOCATION.GlyGenLocation.edges.csv (12.2 MB) | GraphProduct | csv | GlyGen glycosylation site location edges |
| prokn.glygen.glycosyltransferasereaction.has_enzyme_protein_gr.protein.edges | ProKN GlyGen Reaction Enzyme Edges | DDKG_GLYCANS.GlycosyltransferaseReaction.HAS_ENZYME_PROTEIN_GR.Protein.edges.csv (24.4 KB) | GraphProduct | csv | GlyGen glycosyltransferase reaction e... |
| prokn.glygen.glygenlocation.has_amino_acid.aminoacid.edges | ProKN GlyGen Location Amino Acid Edges | DDKG_PROTEOFORM.GlyGenLocation.HAS_AMINO_ACID.AminoAcid.edges.csv (11.9 MB) | GraphProduct | csv | GlyGen location amino acid edges |
| prokn.glygen.glygenresidue.attached_by.glycosylation.edges | ProKN GlyGen Residue Attachment Edges | DDKG_GLYCANS.GlyGenResidue.ATTACHED_BY.Glycosylation.edges.csv (85.9 KB) | GraphProduct | csv | GlyGen residue attached by glycosylat... |
| prokn.glygen.glygenresidue.has_parent.glygenresidue.edges | ProKN GlyGen Residue Parent Edges | DDKG_GLYCANS.GlyGenResidue.HAS_PARENT.GlyGenResidue.edges.csv (18.2 KB) | GraphProduct | csv | GlyGen residue parent edges |
| prokn.glygen.glytoucan.has_canonical_residue.glygenresidue.edges | ProKN GlyGen Canonical Residue Edges | DDKG_GLYCANS.Glytoucan.HAS_CANONICAL_RESIDUE.GlyGenResidue.edges.csv (20.7 MB) | GraphProduct | csv | GlyGen glytoucan canonical residue edges |
| prokn.glygen.glytoucan.has_glycosequence.gyglycosequence.edges | ProKN GlyGen Glycosequence Edges | DDKG_GLYCANS.Glytoucan.HAS_GLYCOSEQUENCE.GlyGenGlycosequence.edges.csv (30.3 MB) | GraphProduct | csv | GlyGen glytoucan glyco-sequence edges |
| prokn.glygen.glytoucan.has_motif.glycanmotif.edges | ProKN GlyGen Motif Edges | DDKG_GLYCANS.Glytoucan.HAS_MOTIF.GlycanMotif.edges.csv (4.2 MB) | GraphProduct | csv | GlyGen glytoucan motif edges |
| prokn.glygen.glytoucan.is_from_source.glygensrc.edges | ProKN GlyGen Source Edges | DDKG_GLYCANS.Glytoucan.IS_FROM_SOURCE.GlyGenSrc.edges.csv (7.4 MB) | GraphProduct | csv | GlyGen glytoucan source edges |
| prokn.glygen.glytoucan.synthesized_by.glycosyltransferasereaction.edges | ProKN GlyGen Synthesized By Edges | DDKG_GLYCANS.Glytoucan.SYNTHESIZED_BY.GlycosyltransferaseReaction.edges.csv (52.2 MB) | GraphProduct | csv | GlyGen glytoucan synthesized by react... |
| prokn.go.goterm.is_a.goterm.edges | ProKN GO Term Hierarchy Edges | GO.GOTerm.IS_A.GOTerm.edges.csv (11.4 MB) | GraphProduct | csv | GO term hierarchy edges |
| prokn.gtexexp.gtexexp.expressed_in.anatomy.edges | ProKN GTExEXP Anatomy Expression Edges | DDKG_GTEXEXP.GTExEXP.EXPRESSED_IN.Anatomy.edges.csv (387.6 MB) | GraphProduct | csv | GTEx expression to anatomy edges (GTE... |
| prokn.gtexexp.gtexexp.expressed_in.gene.edges | ProKN GTExEXP Gene Expression Edges | DDKG_GTEXEXP.GTExEXP.EXPRESSED_IN.Gene.edges.csv (368.8 MB) | GraphProduct | csv | GTEx expression to gene edges (GTExEX... |
| prokn.gtexexp.gtexexp.has_expression.expbins.edges | ProKN GTExEXP Expression Bin Edges | DDKG_GTEXEXP.GTExEXP.HAS_EXPRESSION.EXPBINS.edges.csv (394.4 MB) | GraphProduct | csv | GTEx expression to expression bins edges |
| prokn.impc.impcallele.impc_ensembl_id.impcmousegene.edges | ProKN IMPC Allele to Mouse Gene Edges | IMPC.ImpcAllele.IMPC_ENSEMBL_ID.ImpcMouseGene.edges.csv (29.5 MB) | GraphProduct | csv | IMPC allele to mouse gene edges |
| prokn.impc.impchumangene.interacts_with.impchumangene.edges | ProKN IMPC Human-Human Interaction Edges | IMPC.ImpcHumanGene.BIOLINK_INTERACTS_WITH.ImpcHumanGene.edges.csv (1.2 GB) | GraphProduct | csv | IMPC human gene interacts with human ... |
| prokn.impc.impchumangene.interacts_with.impcmousegene.edges | ProKN IMPC Human-Mouse Interaction Edges | IMPC.ImpcHumanGene.BIOLINK_INTERACTS_WITH.ImpcMouseGene.edges.csv (7.9 MB) | GraphProduct | csv | IMPC human gene interacts with mouse ... |
| prokn.impc.impchumangene.orthologous_to.impcmousegene.edges | ProKN IMPC Ortholog Edges | IMPC.ImpcHumanGene.BIOLINK_ORTHOLOGOUS_TO.ImpcMouseGene.edges.csv (16.0 MB) | GraphProduct | csv | IMPC human gene orthologous to mouse ... |
| prokn.pir.impchumangene.orthologous_to.protein.edges | ProKN PIR Human Gene to Protein Ortholog Edges | PIR.ImpcHumanGene.BIOLINK_ORTHOLOGOUS_TO.Protein.edges.csv (17.2 MB) | GraphProduct | csv | PIR IMPC human gene orthologous to pr... |
| prokn.pir.impcmousegene.has_gene_product.protein.edges | ProKN PIR Mouse Gene Product Edges | PIR.ImpcMouseGene.BIOLINK_HAS_GENE_PRODUCT.Protein.edges.csv (18.6 MB) | GraphProduct | csv | PIR IMPC mouse gene has gene product ... |
| prokn.impc.impcmousegene.interacts_with.impchumangene.edges | ProKN IMPC Mouse-Human Interaction Edges | IMPC.ImpcMouseGene.BIOLINK_INTERACTS_WITH.ImpcHumanGene.edges.csv (25.2 MB) | GraphProduct | csv | IMPC mouse gene interacts with human ... |
| prokn.impc.impcmousegene.interacts_with.impcmousegene.edges | ProKN IMPC Mouse-Mouse Interaction Edges | IMPC.ImpcMouseGene.BIOLINK_INTERACTS_WITH.ImpcMouseGene.edges.csv (337.9 MB) | GraphProduct | csv | IMPC mouse gene interacts with mouse ... |
| prokn.impc.impcmousegene.orthologous_to.impchumangene.edges | ProKN IMPC Mouse-Human Ortholog Edges | IMPC.ImpcMouseGene.IMPC_HUMAN_GENE_ORTHOLOGUES.ImpcHumanGene.edges.csv (5.5 MB) | GraphProduct | csv | IMPC mouse gene orthologous to human ... |
| prokn.impc.impcmousegene.impc_mouse_allele_id.impcallele.edges | ProKN IMPC Mouse Allele ID Edges | IMPC.ImpcMouseGene.IMPC_MOUSE_ALLELE_ID.ImpcAllele.edges.csv (2.3 MB) | GraphProduct | csv | IMPC mouse gene allele ID edges |
| prokn.impc.impcmousegene.impc_mouse_alleles.impcallele.edges | ProKN IMPC Mouse Alleles Edges | IMPC.ImpcMouseGene.IMPC_MOUSE_ALLELES.ImpcAllele.edges.csv (28.0 MB) | GraphProduct | csv | IMPC mouse gene allele membership edges |
| prokn.impc.imppublication.impc_alleles.impcallele.edges | ProKN IMPC Publication Allele Edges | IMPC.ImpcPublication.IMPC_ALLELES.ImpcAllele.edges.csv (4.0 MB) | GraphProduct | csv | IMPC publication allele edges |
| prokn.msigdb.msigdb.chr_band_contains_gene.gene.edges | ProKN MSIGDB Chromosome Band Edges | DDKG_MSIGDB.MSigDB.CHR_BAND_CONTAINS_GENE.Gene.edges.csv (4.9 MB) | GraphProduct | csv | MSIGDB chromosome band contains gene ... |
| prokn.msigdb.msigdb.has_marker_gene.gene.edges | ProKN MSIGDB Marker Gene Edges | DDKG_MSIGDB.MSigDB.HAS_MARKER_GENE.Gene.edges.csv (23.7 MB) | GraphProduct | csv | MSIGDB marker gene edges |
| prokn.msigdb.msigdb.has_signature_gene.gene.edges | ProKN MSIGDB Signature Gene Edges | DDKG_MSIGDB.MSigDB.HAS_SIGNATURE_GENE.Gene.edges.csv (1.6 MB) | GraphProduct | csv | MSIGDB signature gene edges |
| prokn.msigdb.msigdb.pathway_associated_with_gene.gene.edges | ProKN MSIGDB Pathway Gene Edges | DDKG_MSIGDB.MSigDB.PATHWAY_ASSOCIATED_WITH_GENE.Gene.edges.csv (120.1 MB) | GraphProduct | csv | MSIGDB pathway associated with gene e... |
| prokn.msigdb.msigdb.targets_expression_of_gene.gene.edges | ProKN MSIGDB Targets Expression Edges | DDKG_MSIGDB.MSigDB.TARGETS_EXPRESSION_OF_GENE.Gene.edges.csv (149.2 MB) | GraphProduct | csv | MSIGDB targets expression of gene edges |
| prokn.reactome.pathway.event_of.pathway.edges | ProKN Reactome Pathway Event Edges | Reactome.Pathway.PATHWAY_EVENT_OF.Pathway.edges.csv (1.0 MB) | GraphProduct | csv | Reactome pathway event hierarchy edges |
| prokn.lincs_p100.perturbagen.is_used_in.experiment.edges | ProKN LINCS P100 Perturbagen Edges | LINCS_P100.Perturbagen.IS_USED_IN.Experiment.edges.csv (529.1 KB) | GraphProduct | csv | LINCS P100 perturbagen experiment edges |
| prokn.lincs_p100.experiment.perturbation_effect.ptmsite.edges | ProKN LINCS P100 Perturbation Effect Edges | LINCS_P100.Experiment.PERTURBATION_EFFECT.PTMSite.edges.csv (50.1 MB) | GraphProduct | csv | LINCS P100 experiment perturbation ef... |
| prokn.lincs_p100.ptmsite.is_site.site.edges | ProKN LINCS P100 PTM Site Mapping Edges | LINCS_P100.PTMSite.IS_SITE.Site.edges.csv (980 B) | GraphProduct | csv | LINCS P100 PTM site is site of site e... |
| prokn.go.protein.acts_upstream_of.goterm.edges | ProKN GO Acts Upstream Of Edges | GO.Protein.ACTS_UPSTREAM_OF.GOTerm.edges.csv (155.2 KB) | GraphProduct | csv | GO protein acts upstream of GO term e... |
| prokn.go.protein.acts_upstream_of_negative_effect.goterm.edges | ProKN GO Acts Upstream Negative Edges | GO.Protein.ACTS_UPSTREAM_OF_NEGATIVE_EFFECT.GOTerm.edges.csv (10.2 KB) | GraphProduct | csv | GO protein acts upstream of negative ... |
| prokn.go.protein.acts_upstream_of_or_within.goterm.edges | ProKN GO Acts Upstream Or Within Edges | GO.Protein.ACTS_UPSTREAM_OF_OR_WITHIN.GOTerm.edges.csv (697.6 KB) | GraphProduct | csv | GO protein acts upstream of or within... |
| prokn.go.protein.acts_upstream_of_or_within_negative_effect.goterm.edges | ProKN GO Acts Upstream Or Within Negative Edges | GO.Protein.ACTS_UPSTREAM_OF_OR_WITHIN_NEGATIVE_EFFECT.GOTerm.edges.csv (4.2 KB) | GraphProduct | csv | GO protein acts upstream of or within... |
| prokn.go.protein.acts_upstream_of_or_within_positive_effect.goterm.edges | ProKN GO Acts Upstream Or Within Positive Edges | GO.Protein.ACTS_UPSTREAM_OF_OR_WITHIN_POSITIVE_EFFECT.GOTerm.edges.csv (13.6 KB) | GraphProduct | csv | GO protein acts upstream of or within... |
| prokn.go.protein.acts_upstream_of_positive_effect.goterm.edges | ProKN GO Acts Upstream Positive Edges | GO.Protein.ACTS_UPSTREAM_OF_POSITIVE_EFFECT.GOTerm.edges.csv (31.8 KB) | GraphProduct | csv | GO protein acts upstream of positive ... |
| prokn.go.protein.colocalizes_with.goterm.edges | ProKN GO Colocalizes Edges | GO.Protein.COLOCALIZES_WITH.GOTerm.edges.csv (255.4 KB) | GraphProduct | csv | GO protein colocalizes with GO term e... |
| prokn.go.protein.contributes_to.goterm.edges | ProKN GO Contributes To Edges | GO.Protein.CONTRIBUTES_TO.GOTerm.edges.csv (303.3 KB) | GraphProduct | csv | GO protein contributes to GO term edges |
| prokn.go.protein.enables.goterm.edges | ProKN GO Enables Edges | GO.Protein.ENABLES.GOTerm.edges.csv (50.7 MB) | GraphProduct | csv | GO protein enables GO term edges |
| prokn.interpro.protein.has_domain.domain.edges | ProKN InterPro Domain Edges | InterPro.Protein.HAS_DOMAIN.Domain.edges.csv (4.5 MB) | GraphProduct | csv | InterPro protein has domain edges |
| prokn.glygen.protein.has_isoform.isoform.edges | ProKN GlyGen Protein Isoform Edges | DDKG_PROTEOFORM.Protein.HAS_ISOFORM.Isoform.edges.csv (1.3 MB) | GraphProduct | csv | GlyGen protein isoform edges |
| prokn.iptmnet.protein.has_site.site.edges | ProKN iPTMnet Protein Site Edges | iPTMnet.Protein.HAS_SITE.Site.edges.csv (32.6 MB) | GraphProduct | csv | iPTMnet protein has site edges |
| prokn.glygen.protein.has_isoform.protein.edges | ProKN GlyGen Protein Isoform Protein Edges | DDKG_PROTEOFORM.Protein.HAS_ISOFORM.Protein.edges.csv (637.8 KB) | GraphProduct | csv | GlyGen protein isoform protein edges |
| prokn.uniprotkb.protein.has_site.site.edges | ProKN UniProtKB Protein Site Edges | UniProtKB.Protein.HAS_SITE.Site.edges.csv (25.6 MB) | GraphProduct | csv | UniProtKB protein has site edges |
| prokn.uniprotkb.protein.has_variant.variant.edges | ProKN UniProtKB Variant Edges | UniProtKB.Protein.HAS_VARIANT.Variant.edges.csv (18.8 MB) | GraphProduct | csv | UniProtKB protein variant edges |
| prokn.emind.protein.has_variant.variant.edges | ProKN eMIND Variant Edges | eMIND.Protein.HAS_VARIANT.Variant.edges.csv (58.7 KB) | GraphProduct | csv | eMIND protein variant edges |
| prokn.imex.protein.interacts_with.protein.edges | ProKN IMEx Protein Interaction Edges | IMEx.Protein.INTERACTS_WITH.Protein.edges.csv (346.5 MB) | GraphProduct | csv | IMEx protein interacts with protein e... |
| prokn.go.protein.involved_in.goterm.edges | ProKN GO Involved In Edges | GO.Protein.INVOLVED_IN.GOTerm.edges.csv (41.4 MB) | GraphProduct | csv | GO protein involved in GO term edges |
| prokn.go.protein.is_active_in.goterm.edges | ProKN GO Active In Edges | GO.Protein.IS_ACTIVE_IN.GOTerm.edges.csv (1.6 MB) | GraphProduct | csv | GO protein active in GO term edges |
| prokn.go.protein.located_in.goterm.edges | ProKN GO Located In Edges | GO.Protein.LOCATED_IN.GOTerm.edges.csv (48.4 MB) | GraphProduct | csv | GO protein located in GO term edges |
| prokn.go.protein.not_acts_upstream_of_or_within.goterm.edges | ProKN GO Not Acts Upstream Or Within Edges | GO.Protein.NOT_ACTS_UPSTREAM_OF_OR_WITHIN.GOTerm.edges.csv (1.8 KB) | GraphProduct | csv | GO protein not acts upstream of or wi... |
| prokn.go.protein.not_acts_upstream_of_or_within_negative_effect.goterm.edges | ProKN GO Not Acts Upstream Negative Edges | GO.Protein.NOT_ACTS_UPSTREAM_OF_OR_WITHIN_NEGATIVE_EFFECT.GOTerm.edges.csv (455 B) | GraphProduct | csv | GO protein not acts upstream of or wi... |
| prokn.go.protein.not_colocalizes_with.goterm.edges | ProKN GO Not Colocalizes Edges | GO.Protein.NOT_COLOCALIZES_WITH.GOTerm.edges.csv (3.3 KB) | GraphProduct | csv | GO protein not colocalizes with GO te... |
| prokn.go.protein.not_contributes_to.goterm.edges | ProKN GO Not Contributes Edges | GO.Protein.NOT_CONTRIBUTES_TO.GOTerm.edges.csv (3.1 KB) | GraphProduct | csv | GO protein not contributes to GO term... |
| prokn.go.protein.not_enables.goterm.edges | ProKN GO Not Enables Edges | GO.Protein.NOT_ENABLES.GOTerm.edges.csv (126.7 KB) | GraphProduct | csv | GO protein not enables GO term edges |
| prokn.go.protein.not_involved_in.goterm.edges | ProKN GO Not Involved In Edges | GO.Protein.NOT_INVOLVED_IN.GOTerm.edges.csv (139.8 KB) | GraphProduct | csv | GO protein not involved in GO term edges |
| prokn.go.protein.not_is_active_in.goterm.edges | ProKN GO Not Active In Edges | GO.Protein.NOT_IS_ACTIVE_IN.GOTerm.edges.csv (893 B) | GraphProduct | csv | GO protein not active in GO term edges |
| prokn.go.protein.not_located_in.goterm.edges | ProKN GO Not Located In Edges | GO.Protein.NOT_LOCATED_IN.GOTerm.edges.csv (51.5 KB) | GraphProduct | csv | GO protein not located in GO term edges |
| prokn.go.protein.not_part_of.goterm.edges | ProKN GO Not Part Of Edges | GO.Protein.NOT_PART_OF.GOTerm.edges.csv (4.6 KB) | GraphProduct | csv | GO protein not part of GO term edges |
| prokn.go.protein.part_of.goterm.edges | ProKN GO Part Of Edges | GO.Protein.PART_OF.GOTerm.edges.csv (3.5 MB) | GraphProduct | csv | GO protein part of GO term edges |
| prokn.imex.protein.participates_in.complex.edges | ProKN IMEx Protein Participates In Complex Edges | IMEx.Protein.PARTICIPATES_IN.Complex.edges.csv (17.9 MB) | GraphProduct | csv | IMEx protein participates in complex ... |
| prokn.reactome.protein.participates_in.pathway.edges | ProKN Reactome Protein Pathway Edges | Reactome.Protein.PARTICIPATES_IN.Pathway.edges.csv (16.3 MB) | GraphProduct | csv | Reactome protein participates in path... |
| prokn.iptmnet.protein.catalyzes.ptmsite.edges | ProKN iPTMnet Protein Catalyzes PTM Site Edges | iPTMnet.Protein.CATALYZES.PTMSite.edges.csv (3.9 MB) | GraphProduct | csv | iPTMnet protein catalyzes PTM site edges |
| prokn.emind.variant.associated_with.disease.edges | ProKN eMIND Variant Disease Edges | eMIND.Variant.ASSOCIATED_WITH.Disease.edges.csv (1.6 KB) | GraphProduct | csv | eMIND variant associated with disease... |
| prokn.emind.variant.impact.disease.edges | ProKN eMIND Variant Impact Disease Edges | eMIND.Variant.IMPACT.Disease.edges.csv (68.0 KB) | GraphProduct | csv | eMIND variant impact on disease edges |
| prokn.emind.variant.impact.protein.edges | ProKN eMIND Variant Impact Protein Edges | eMIND.Variant.IMPACT.Protein.edges.csv (1.3 KB) | GraphProduct | csv | eMIND variant impact on protein edges |
| prokn.explorer | Protein Knowledge Network Explorer | explorer | GraphicalInterface | http | Web explorer for the Protein Knowledg... |
| prokn.downloads | Protein Knowledge Network Downloads | downloads | Product | http | Bulk downloads page listing current P... |
| prokn.api | Protein Knowledge Network REST API | restapi | ProgrammingInterface | http | REST API for the Protein Knowledge Ne... |
| prokn.mcp | ProKN MCP Interface | mcp | ProgrammingInterface | http | Hosted Model Context Protocol endpoin... |
| prokn.tpf | Protein Knowledge Network TPF | prokn | ProgrammingInterface | ❔ | Triple Pattern Fragments endpoint for... |
| prokn.sparql | Protein Knowledge Network SPARQL | sparql | ProgrammingInterface | ❔ | SPARQL endpoint for Protein Knowledge... |
Protein Knowledge Network (ProKN) is a protein-centric knowledge graph that links CFDE datasets with curated biomedical resources spanning protein function, post-translational modification, pathway biology, gene expression, genotype-phenotype associations, and chemical perturbation data. The graph is designed to support cross-domain exploration of functional genomics and systems-level responses to perturbations.
The current public ProKN site exposes several complementary access paths. The network explorer supports interactive browsing, the REST API publishes resource-specific endpoints plus graph search operations, and the FRINK Triple Pattern Fragments endpoint provides linked-data access for graph-pattern queries. Bulk node and edge exports are indexed from the downloads page, which is the current authoritative landing page for public CSV exports.
Recent ProKN infrastructure also includes an MCP server implementation for AI clients. The MCP server source is published separately from the main website and documents both local deployment and the hosted MCP entry point used by compatible clients.
Created: January 23, 2026 | Last modified: May 21, 2026