pubchem

is a Data Source.

PubChem is an open chemistry database that collects information on chemical structures, identifiers, chemical and physical properties, biological activities, patents, health, safety, toxicity data, and other information.

Domains

chemistry and biochemistry, health

License

Public Domain

Homepage

pubchem

Repository

GitHub

Infores ID

infores:pubchem

FAIRsharing ID

Unknown

Product Summary

Products

From this Resource
ID Name URL Category Format Description
pubchem.compounds.asn PubChem Compounds ASN ASN Product xml Compound structures, properties, and ...
pubchem.compounds.sdf PubChem Compounds SDF SDF Product sdf Compound structures, properties, and ...
pubchem.substances.asn PubChem Substances ASN ASN Product xml PubChem substance information in ASN....
pubchem.substances.sdf PubChem Substances SDF SDF Product sdf PubChem substance information in SDF ...
pubchem.bioassay.asn PubChem BioAssay ASN ASN Product xml PubChem BioAssay data in ASN.1 format
pubchem.bioassay.xml PubChem BioAssay XML XML Product xml PubChem BioAssay data in XML format
pubchem.pug.rest PubChem PUG REST API pug-rest ProgrammingInterface The PubChem Power User Gateway (PUG) ...
From other Resources
ID Name URL Category Format Description
biomarkerkg.nodes.compound BKG Compound Nodes Compound.nodes.zip (871 B) GraphProduct csv Nodes from PubChem Database
alzkb.browser AlzKB Graph Database Browser login GraphicalInterface http A browser interface for a knowledge g...
alzkb.data AlzKB Data Release (Version 2.0.0) v2.0.0 GraphProduct Memgraph data release for AlzKB.
pharmkg.graph PharmKG graph 4077338 GraphProduct Cleaned benchmark graph (PharmKG-8k) ...
microbiomekg.api MicrobiomeKG Plover API mbkp ProgrammingInterface http TRAPI web API for querying MicrobiomeKG
icees-kg.graph KGX distribution of the ICEES Exposures KP 1.5.0 GraphProduct kgx-jsonl KGX distribution of the ICEES Exposur...
icees-kg.trapi ICEES KG TRAPI API icees-kg-trapi ProgrammingInterface http Translator Reasoner API (TRAPI) endpo...
icees-kg.metadata ICEES KG Metadata metadata-metadata-get-icees-kg Product json Meta knowledge graph and metadata des...
forum.graph.dump FORUM Knowledge Graph Dump share.tar.gz GraphProduct Downloadable knowledge graph dump in ...
unibiomap.links UniBioMap Graph Links unibiomap.links.csv (1.3 GB) GraphProduct csv Core UniBioMap graph edges file.
unibiomap.auxs UniBioMap Graph Auxiliaries unibiomap.auxs.tsv (563.9 MB) GraphProduct tsv Auxiliary UniBioMap graph annotations...
unibiomap.pred UniBioMap Predicted Graph unibiomap.pred.csv (2.3 GB) GraphProduct csv Predicted UniBioMap graph edges with ...
unibiomap.pred.full UniBioMap Predicted Graph (Full) unibiomap.pred.full.csv (5.9 GB) GraphProduct csv Full unfiltered UniBioMap predicted g...

Details

PubChem is a database of chemical molecules and their activities against biological assays maintained by the National Center for Biotechnology Information (NCBI), a component of the National Library of Medicine, which is part of the United States National Institutes of Health (NIH).

The system contains three primary databases:

  • PubChem Substance: Contains more than 309 million records of chemical samples submitted by over 900 data sources
  • PubChem Compound: Contains more than 114 million unique chemical structures derived from PubChem Substance
  • PubChem BioAssay: Contains bioactivity results from over 1.3 million high-throughput screening programs

PubChem data is available through a web interface, programmatically via the PUG REST API, and as bulk downloads via FTP. The system supports structure searches, chemical property information, biological activities, safety and toxicity information, patents, literature citations, and links to related resources.

All PubChem data is in the public domain and can be freely downloaded and used for both commercial and non-commercial purposes.

Is this information incorrect or incomplete? Request an update.

Created: May 04, 2025 | Last modified: February 20, 2026