rhea

is a Data Source.

Rhea is an expert-curated knowledgebase of chemical and transport reactions of biological interest.

Domains

chemistry and biochemistry

License

CC-BY-4.0

Homepage

rhea

Repository

Unknown

Infores ID

infores:rhea

FAIRsharing ID

Unknown

Product Summary

Contacts

Products

From other Resources
ID Name URL Category Format Description
obo-db-ingest.rhea.obo rhea OBO rhea.obo (4.6 MB) Product obo rhea OBO
obo-db-ingest.rhea.owl rhea OWL rhea.owl.gz (7.6 MB) Product owl rhea OWL
obo-db-ingest.rhea.json rhea OBO Graph JSON rhea.json.gz (5.0 MB) Product json rhea OBO Graph JSON
obo-db-ingest.rhea.sssom.tsv rhea SSSOM rhea.sssom.tsv (150.6 KB) MappingProduct sssom rhea SSSOM
microbiomekg.api MicrobiomeKG Plover API mbkp ProgrammingInterface http TRAPI web API for querying MicrobiomeKG
kg-microbe.graph.raw KG-Microbe KGX Graph - Raw KGMicrobe-raw-20250222.tar.gz (11.6 GB) GraphProduct kgx Raw source files for all KG-Microbe f...
kg-microbe.graph.core KG-Microbe KGX Graph - Core latest GraphProduct kgx The core KG KG-Microbe-Core with onto...
kg-microbe.graph.biomedical KG-Microbe KGX Graph - Biomedical latest GraphProduct kgx Core plus human biomedical data (onto...
kg-microbe.graph.function KG-Microbe KGX Graph - Function KGMicrobe-function-20250222.tar.gz (4.3 GB) GraphProduct kgx Core plus Uniprot genome annotations
kg-microbe.graph.biomedical-function KG-Microbe KGX Graph - Biomedical-Function KGMicrobe-biomedical-function-20250222.tar.gz (4.3 GB) GraphProduct kgx Biomedical plus Uniprot genome annota...
swisslipid.enzymes SwissLipids Enzymes file.php?cas=download_files&file=enzymes.tsv (123.8 KB) Product tsv TSV export of lipid-related enzymes w...
obo-db-ingest.rhea.tsv rhea Nodes TSV rhea.tsv (958.8 KB) Product tsv rhea Nodes TSV

Details

Rhea is an expert-curated knowledgebase of chemical and transport reactions of biological interest. Enzyme-catalyzed and spontaneously occurring reactions are curated from peer-reviewed literature and represented in a computationally tractable manner by using the ChEBI (Chemical Entities of Biological Interest) ontology to describe reaction participants.

Rhea covers the reactions described by the IUBMB Enzyme Nomenclature as well as many additional reactions and can be used for enzyme annotation, genome-scale metabolic modeling and omics-related analyses. Rhea is the standard for enzyme and transporter annotation in UniProtKB.

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Created: March 09, 2025 | Last modified: February 20, 2026