sennet

is a Data Source.

The Cellular Senescence Network (SenNet) is an NIH Common Fund program that aims to comprehensively identify and characterize senescent cells across the human lifespan and in various disease states. SenNet provides spatial molecular maps of senescent cells in tissues, developing and applying cutting-edge technologies for detecting cellular senescence. The consortium generates multi-omics data, imaging data, and develops computational tools to advance understanding of how senescent cells contribute to aging and age-related diseases.

Domains

health, biomedical, anatomy and development, genomics, precision medicine

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sennet

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Product Summary

Products

From this Resource
ID Name URL Category Format Description
sennet.portal SenNet Data Portal data.sennetconsortium.org GraphicalInterface http Data portal for browsing and accessin...
sennet.data SenNet Multi-Omics Data data.sennetconsortium.org Product mixed Multi-omics datasets of senescent cells
sennet.api SenNet API sennetconsortium.org ProgrammingInterface http API for programmatic access to SenNet...
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Details

SenNet - Cellular Senescence Network

Overview

The Cellular Senescence Network (SenNet) is an NIH Common Fund program that aims to comprehensively identify and characterize senescent cells across the human lifespan and in various disease states.

Launched in 2021, SenNet develops and applies cutting-edge technologies to create spatial molecular maps of senescent cells in human tissues, advancing understanding of how these cells contribute to aging and age-related diseases.

Key Features

  • Senescence Biomarkers: Development and validation of markers for detecting senescent cells
  • Multi-Omics Profiling: Genomics, transcriptomics, proteomics, and metabolomics of senescent cells
  • Spatial Mapping: Tissue-level spatial distribution of senescent cells
  • Technology Development: Novel methods for senescence detection and characterization
  • Public Data: Open access to datasets, protocols, and analysis tools
  • Cross-Tissue Studies: Comprehensive mapping across multiple human tissues

Research Applications

  • Aging biology research
  • Age-related disease mechanisms
  • Therapeutic target identification
  • Senolytic drug development
  • Biomarker discovery
  • Understanding tissue-specific aging

Products

SenNet Data Portal

Web-based portal for exploring, visualizing, and downloading SenNet datasets including imaging, omics, and metadata.

SenNet Multi-Omics Data

Comprehensive molecular datasets characterizing senescent cells across tissues and conditions, including transcriptomics, proteomics, and metabolomics.

SenNet API

Programmatic interface for accessing SenNet data and integrating with computational workflows.

Information Resource ID

This resource has the Information Resource identifier: infores:sennet

Domains

  • Health
  • Biomedical
  • Anatomy and Development
  • Genomics
  • Precision Medicine

Taxon Coverage

Human (NCBITaxon:9606)

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Created: November 05, 2025 | Last modified: November 05, 2025