is a Data Source.
SIDER (Side Effect Resource) contains information on marketed medicines and their recorded adverse drug reactions. The information is extracted from public documents and package inserts, including side effect frequency, drug and side effect classifications, and links to further information.
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| sider.web | SIDER Web Interface | sideeffects.embl.de | Graphical Interface | http | Web interface that allows searching a... |
| sider.drug_names | SIDER Drug Names | drug_names.tsv (33.9 KB) | Product | tsv | Tab-separated file mapping drugs to t... |
| sider.drug_atc | SIDER Drug ATC Codes | drug_atc.tsv (32.0 KB) | Mapping | tsv | Tab-separated file mapping drugs to t... |
| sider.meddra_all_indications | SIDER MedDRA All Indications | meddra_all_indications.tsv.gz (336.6 KB) | Product | tsv | Tab-separated file containing all dru... |
| sider.meddra_all_se | SIDER MedDRA All Side Effects | meddra_all_se.tsv.gz (2.3 MB) | Product | tsv | Tab-separated file containing all sid... |
| sider.meddra_freq | SIDER MedDRA Frequency | meddra_freq.tsv.gz (2.0 MB) | Product | tsv | Tab-separated file containing side ef... |
| sider.meddra_all_label_indications | SIDER MedDRA All Label Indications | meddra_all_label_indications.tsv.gz (5.6 MB) | Product | tsv | Tab-separated file containing all ori... |
| sider.meddra_all_label_se | SIDER MedDRA All Label Side Effects | meddra_all_label_se.tsv.gz (40.6 MB) | Product | tsv | Tab-separated file containing all ori... |
| sider.meddra | SIDER MedDRA Dictionary | meddra.tsv.gz (1.0 MB) | Product | tsv | Tab-separated file mapping MedDRA ter... |
| ID | Name | URL | Category | Format | Relation | Description |
|---|---|---|---|---|---|---|
| spoke.graph | SPOKE Graph | data-tools | Graph | http | had primary source | The SPOKE knowledge graph containing ... |
| alzkb.browser | AlzKB Graph Database Browser | login | Graphical Interface | http | had primary source | A browser interface for a knowledge g... |
| alzkb.data | AlzKB Data Release (Version 2.0.0) | v2.0.0 | Graph | mixed | had primary source | Memgraph data release for AlzKB. |
| bioteque.embeddings | Bioteque Embeddings | embeddings | Product | mixed | had primary source | Network embeddings of the Bioteque gr... |
| indra.cogex.code | INDRA CoGEx Build Code | indra_cogex | Process | python | had primary source | INDRA CoGEx is a graph database integ... |
| pharmkg.graph | PharmKG graph | 4077338 | Graph | mixed | had primary source | Cleaned benchmark graph (PharmKG-8k) ... |
| clinicalkg.graph | CKG Graph Dump | 1 | Graph | mixed | had primary source | Neo4j database dump of the Clinical K... |
| cancer-genome-interpreter.clinicalkg.graph | CKG Graph Dump | 1 | Graph | mixed | had primary source | Neo4j database dump of the Clinical K... |
| ibkh.graph | iBKH Knowledge Graph | ❔ | Graph | mixed | had primary source | The integrative Biomedical Knowledge ... |
| translator.sider.graph | Translator SIDER KGX Graph | latest | Graph | kgx-jsonl | had primary source | KGX JSONL graph package for SIDER dis... |
| unibiomap.links | UniBioMap Graph Links | unibiomap.links.csv (1.3 GB) | Graph | csv | had primary source | Core UniBioMap graph edges file. |
| unibiomap.auxs | UniBioMap Graph Auxiliaries | unibiomap.auxs.tsv (563.9 MB) | Graph | tsv | had primary source | Auxiliary UniBioMap graph annotations... |
| unibiomap.pred | UniBioMap Predicted Graph | unibiomap.pred.csv (2.3 GB) | Graph | csv | had primary source | Predicted UniBioMap graph edges with ... |
| unibiomap.pred.full | UniBioMap Predicted Graph (Full) | unibiomap.pred.full.csv (5.9 GB) | Graph | csv | had primary source | Full unfiltered UniBioMap predicted g... |
| translator.translator_kg.graph | Translator Aggregate KGX Graph | latest | Graph | kgx-jsonl | had primary source | Aggregated KGX JSONL graph package co... |
| hetionet.neo4j | Hetionet v1.0 Neo4j Database | browser | Graphical Interface | http | had primary source | Browser for complete Hetionet v1.0 gr... |
| hetionet.data.json | Hetionet v1.0 JSON | hetionet-v1.0.json.bz2 (131 B) | Graph | json | had primary source | Hetionet v1.0 in JSON format |
| hetionet.data.neo4j | Hetionet v1.0 Neo4j | hetionet-v1.0.db.tar.bz2 (132 B) | Graph | neo4j | had primary source | Hetionet v1.0 as a Neo4j database |
| hetionet.data.edges | Hetionet v1.0 edges (SIF) | hetionet-v1.0-edges.sif.gz (131 B) | Graph | sif | had primary source | Hetionet v1.0 as SIF edges |
| hetionet.data.nodes | Hetionet v1.0 nodes (TSV) | hetionet-v1.0-nodes.tsv (417.1 KB) | Graph | tsv | had primary source | Hetionet v1.0 as TSV nodes |
| hetionet.hetnetpy | hetnetpy | hetnetpy | Process | python | had primary source | Python package for creating, querying... |
| hetionet.search | Hetnet Connectivity Search | search | Graphical Interface | http | had primary source | Web application to search and explore... |
| oregano.graph | OREGANO Knowledge Graph | Graphs | Graph | http | was derived from | The OREGANO knowledge graph dataset i... |
| pharmebinet.json | PharMeBINet JSON Release | content (3.4 GB) | Graph | json | was derived from | PharMeBINet V3 JSON release (Zenodo v... |
| pharmebinet.tsv | PharMeBINet TSV Release | content (3.5 GB) | Graph | tsv | was derived from | PharMeBINet V3 TSV release (Zenodo ve... |
| pharmebinet.graphml | PharMeBINet GraphML Release | content (3.8 GB) | Graph | mixed | was derived from | PharMeBINet V3 GraphML release (Zenod... |
| pharmebinet.neo4j | PharMeBINet Neo4j Database | content (7.7 GB) | Graph | neo4j | was derived from | PharMeBINet V3 Neo4j database release... |
| pharmebinet.neo4j.dump | PharMeBINet Neo4j Dump | content (7.5 GB) | Graph | neo4j | was derived from | PharMeBINet V3 Neo4j dump release (Ze... |
| molepro.graph.nodes | Nodes for Molecular Data KP | nodes.tsv (3.4 GB) | Graph | kgx | had primary source | KGX nodes for Molecular Data KP |
| molepro.graph.edges | Edges for Molecular Data KP | edges.tsv (18.8 GB) | Graph | kgx | had primary source | KGX edges for Molecular Data KP |
| pharmdb.graph | PharmDB-K Graph | ❔ | Graph | http | had primary source | Integrated pharmacological knowledge ... |
| primekg.graph ⚠ | PrimeKG Full Dataset | 6180620 | Graph | csv | had primary source | The full PrimeKG dataset containing d... |
| spoke-okn.graph | SPOKE-OKN Graph | spoke.ucsf.edu | Graph | ttl | was influenced by | The SPOKE-OKN knowledge graph, an OKN... |
| molepro.api | MolePro API | api | Programming Interface | http | had primary source | MolePro API providing access to the k... |
| molepro.trapi | MolePro TRAPI Interface | ui | Programming Interface | http | had primary source | TRAPI-compliant interface for MolePro... |
| molepro.catalog | MolePro Knowledge Sources Catalog | transformers (2.0 MB) | Product | json | had primary source | Catalog of MolePro knowledge sources ... |
| mychem.api | MyChem.info API | query | Programming Interface | json | had primary source | MyChem.info REST API (v1) for queryin... |
| drugenrichr.libraries | DrugEnrichr Drug Set Libraries | datasetStatistics (4.2 KB) | Product | json | had primary source | Statistics for the 29 drug set librar... |
| drugmonizome.libraries ⚠ | Drugmonizome Drug Set Libraries | libraries | Product | json | was derived from | The 35 Drugmonizome drug set librarie... |
| sep-l1000.portal | SEP-L1000 Web Portal | SEP-L1000 | Graphical Interface | http | was derived from | Web portal for browsing and searching... |
| sep-l1000.sider | SEP-L1000 SIDER Side Effect Matrix | SIDER_PTs.csv.gz (165.9 KB) | Product | csv | was derived from | On-label drug-ADR matrix (834 drugs b... |
SIDER (Side Effect Resource) is a database of drugs and their side effects, which was developed at the European Molecular Biology Laboratory (EMBL). The database contains information extracted from public documents and package inserts, providing valuable data on marketed medicines and their recorded adverse drug reactions.
SIDER 4.1, released on October 21, 2015, contains information on 1,430 drugs and 5,868 side effects, totaling 139,756 drug-side effect pairs. The database uses the MedDRA dictionary (version 16.1) to standardize side effect terminology and provides access to both preferred terms and lower-level terms.
The database includes:
SIDER is linked to other databases like STITCH and PubChem through compound identifiers, allowing for integration with other biomedical resources.
The project is no longer actively maintained or updated as it lacks funding for further development. The most recent data is from 2015 and is therefore considered out of date. However, the resource remains valuable for historical research and as a reference for drug side effect data.
Created: May 29, 2025 | Last modified: September 23, 2026