is a Data Source.
SIMAP (Similarity Matrix of Proteins) was a comprehensive database of pre-calculated all-against-all protein sequence similarities, protein domains, functional annotations, and clusters. Developed at MIPS (Munich Information Center for Protein Sequences) / GSF / Helmholtz Munich and later maintained at the Technical University of Munich (TUM), it provided a continuously updated similarity matrix covering tens of millions of non-redundant protein sequences from UniProt and other sources, and was used as an upstream resource by integrative protein interaction and annotation systems. The project appears discontinued, as its historical hosts (MIPS/Helmholtz Munich and the TUM webclu server) no longer resolve and no successor host is currently reachable.
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| simap.portal ⚠ | SIMAP Portal | simap | Product | http | Legacy SIMAP homepage used for sequen... |
| ID | Name | URL | Category | Format | Relation | Description |
|---|---|---|---|---|---|---|
| string.protein.links | STRING Protein Links | protein.links.v12.0.txt.gz (128.7 GB) | GraphProduct | txt | had primary source | protein network data (full network, s... |
| string.protein.links.detailed | STRING Protein Links Detailed | protein.links.detailed.v12.0.txt.gz (189.6 GB) | GraphProduct | txt | had primary source | protein network data (full network, i... |
| string.protein.links.full | STRING Protein Links Full | protein.links.full.v12.0.txt.gz (199.6 GB) | GraphProduct | txt | had primary source | protein network data (full network, i... |
| string.protein.physical.links | STRING Protein Physical Links | protein.physical.links.v12.0.txt.gz (11.1 GB) | GraphProduct | txt | had primary source | protein network data (physical subnet... |
| string.protein.physical.links.detailed | STRING Protein Physical Links Detailed | protein.physical.links.detailed.v12.0.txt.gz (13.8 GB) | GraphProduct | txt | had primary source | protein network data (physical subnet... |
| string.protein.physical.links.full | STRING Protein Physical Links Full | protein.physical.links.full.v12.0.txt.gz (14.5 GB) | GraphProduct | txt | had primary source | protein network data (physical subnet... |
| string.cog.links | STRING COG Links | COG.links.v12.0.txt.gz (176.8 MB) | GraphProduct | txt | had primary source | association scores between orthologou... |
| string.cog.links.detailed | STRING COG Links Detailed | COG.links.detailed.v12.0.txt.gz (238.7 MB) | GraphProduct | txt | had primary source | association scores (incl. subscores p... |
| string.database | STRING Database Network Schema | network_schema.v12.0.sql.gz (262.2 GB) | GraphProduct | postgres | had primary source | full database, part II: the networks ... |
| genecards.web.interface | GeneCards Web Interface | www.genecards.org | GraphicalInterface | http | had primary source | Web-based interface for searching and... |
SIMAP (Similarity Matrix of Proteins) was a database of pre-calculated all-against-all protein sequence similarities, domains, annotations, and clusters, developed at MIPS / Helmholtz Munich and later the Technical University of Munich. It is now inactive: its historical hosts no longer resolve and no live successor was found. It remains referenced here as a legacy upstream protein-similarity data source for downstream resources such as STRING.
Created: February 18, 2026 | Last modified: June 27, 2026