treatkb

is a Data Source.

TreatKB is a text-mined knowledge base of drug-treats-disease (treatment) relationships developed by the Rong Xu lab at Case Western Reserve University. Treatment pairs are extracted and combined from multiple lines of evidence, including MEDLINE/PubMed literature, the FDA Adverse Event Reporting System (FAERS), and ClinicalTrials.gov records, alongside a curated gold-standard set of drug-disease treatment pairs. The data are distributed as plain-text files from the Xu lab public data server. TreatKB has been used as a source to construct GP-KG.

License

Not specified

Homepage

treatkb

Repository

Unknown

Infores ID

Unknown

FAIRsharing ID

Unknown

Product Summary

Products

From this Resource
ID Name URL Category Format Description
treatkb.publication TreatKB Method Publication 1471-2105-14-181 DocumentationProduct Peer-reviewed publication from the Xu...
treatkb.goldstandard TreatKB gold-standard treatment pairs drug_disease_goldstandard.txt (328.3 KB) Product txt Curated gold-standard set of drug-dis...
From other Resources
ID Name URL Category Format Relation Description
gp-kg.graph GP-KG GP_KG.txt (46.2 MB) GraphProduct txt was derived from GP_KG.txt

Details

TreatKB

Overview

TreatKB is a text-mined knowledge base of drug-treats-disease relationships built by the Rong Xu lab at Case Western Reserve University. It compiles treatment pairs by integrating evidence from multiple biomedical sources, including the FDA Adverse Event Reporting System (FAERS), FDA drug labels, MEDLINE/PubMed literature, and clinical trials.

Availability

TreatKB data are distributed as plain-text files from the Xu lab public data server at http://nlp.case.edu/public/data/treatKB/, including a curated gold-standard set of drug-disease treatment pairs and companion evidence-count files derived from MEDLINE, FAERS, and ClinicalTrials.gov. These downloads resolve live. There is no dedicated interactive portal, and the underlying method dates to 2013, but the files remain publicly accessible.

Use

TreatKB has been used as a source dataset in the construction of GP-KG.

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Created: June 18, 2026 | Last modified: July 02, 2026