is a Data Source.
InterPro is a database of protein families, domains and functional sites in which identifiable features found in known proteins can be applied to unknown protein sequences.
infores:interpro
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| interpro.web | InterPro Web Interface | interpro | Graphical Interface | http | Web interface for browsing and search... |
| interpro.api | InterPro API | api | Programming Interface | http | RESTful API for programmatic access t... |
| interpro.interproscan | InterProScan | interproscan-5.74-105.0-64-bit.tar.gz (6.7 GB) | Process | java | Software package for scanning protein... |
| interpro.entry_list | InterPro Entry List | entry.list (2.5 MB) | Data Model | tsv | Complete list of InterPro entries wit... |
| interpro.xml | InterPro XML | interpro.xml.gz (38.6 MB) | Data Model | xml | Complete InterPro database in XML for... |
| interpro.match_complete | InterPro Match Complete | match_complete.xml.gz (83.1 GB) | Mapping | xml | Complete set of matches between prote... |
| interpro.uniparc_match | UniParc Match | uniparc_match.tar.gz (308.5 GB) | Mapping | xml | InterPro matches for UniParc protein ... |
| interpro.protein2ipr | Protein to InterPro Mappings | protein2ipr.dat.gz (19.5 GB) | Mapping | tsv | Mappings of protein sequences to Inte... |
| interpro.parent_child_tree | Parent-Child Tree | ParentChildTreeFile.txt (612.9 KB) | Data Model | tsv | Hierarchical relationships between In... |
| interpro.interpro2go | InterPro to GO Mappings | interpro2go (2.9 MB) | Mapping | tsv | Mappings between InterPro entries and... |
| ID | Name | URL | Category | Format | Relation | Description |
|---|---|---|---|---|---|---|
| spoke.graph | SPOKE Graph | data-tools | Graph | http | had primary source | The SPOKE knowledge graph containing ... |
| bioteque.embeddings | Bioteque Embeddings | embeddings | Product | mixed | had primary source | Network embeddings of the Bioteque gr... |
| mechreponet.kg | MechRepoNet Knowledge Graph | publication | Product | mixed | had primary source | The MechRepoNet knowledge graph in it... |
| drugmechdb.graph | DrugMechDB Graph Dataset | zenodo.8139357 | Graph | mixed | had primary source | Curated mechanistic drug–disease path... |
| obo-db-ingest.interpro.obo | interpro OBO | interpro.obo (1.1 MB) | Product | obo | had primary source | interpro OBO |
| obo-db-ingest.interpro.owl | interpro OWL | interpro.owl (1.3 MB) | Product | owl | had primary source | interpro OWL |
| obo-db-ingest.interpro.json | interpro OBO Graph JSON | interpro.json (1.1 MB) | Product | json | had primary source | interpro OBO Graph JSON |
| goa.mapping-files | GO Mapping Files | external2go | Mapping | txt | had primary source | Files containing transitive assignmen... |
| kinace.portal | KiNet Web Portal | kinet.kinametrix.com | Graphical Interface | http | was derived from | Interactive Shiny web interface for e... |
| string.protein.links | STRING Protein Links | protein.links.v12.0.txt.gz (128.7 GB) | Graph | txt | had primary source | protein network data (full network, s... |
| string.protein.links.detailed | STRING Protein Links Detailed | protein.links.detailed.v12.0.txt.gz (189.6 GB) | Graph | txt | had primary source | protein network data (full network, i... |
| string.protein.links.full | STRING Protein Links Full | protein.links.full.v12.0.txt.gz (199.6 GB) | Graph | txt | had primary source | protein network data (full network, i... |
| string.protein.physical.links | STRING Protein Physical Links | protein.physical.links.v12.0.txt.gz (11.1 GB) | Graph | txt | had primary source | protein network data (physical subnet... |
| string.protein.physical.links.detailed | STRING Protein Physical Links Detailed | protein.physical.links.detailed.v12.0.txt.gz (13.8 GB) | Graph | txt | had primary source | protein network data (physical subnet... |
| string.protein.physical.links.full | STRING Protein Physical Links Full | protein.physical.links.full.v12.0.txt.gz (14.5 GB) | Graph | txt | had primary source | protein network data (physical subnet... |
| string.cog.links | STRING COG Links | COG.links.v12.0.txt.gz (176.8 MB) | Graph | txt | had primary source | association scores between orthologou... |
| string.cog.links.detailed | STRING COG Links Detailed | COG.links.detailed.v12.0.txt.gz (238.7 MB) | Graph | txt | had primary source | association scores (incl. subscores p... |
| string.database | STRING Database Network Schema | network_schema.v12.0.sql.gz (262.2 GB) | Graph | postgres | had primary source | full database, part II: the networks ... |
| obo-db-ingest.interpro.tsv | interpro Nodes TSV | interpro.tsv (681.5 KB) | Product | tsv | had primary source | interpro Nodes TSV |
| prokn.interpro.domain.is_a.domain.edges | ProKN InterPro Domain Hierarchy Edges | InterPro.Domain.IS_A.Domain.edges.csv (167.0 KB) | Graph | csv | had primary source | InterPro domain is_a domain edges |
| prokn.interpro.protein.has_domain.domain.edges | ProKN InterPro Domain Edges | InterPro.Protein.HAS_DOMAIN.Domain.edges.csv (4.5 MB) | Graph | csv | had primary source | InterPro protein has domain edges |
| genophenoenvo-kg.data | GenoPhenoEnvo KG Data | genophenoenvo | Graph | kgx | had primary source | Merged knowledge graph data files con... |
| disprot.downloads | DisProt Downloads | download | Product | json | was informed by | Bulk download of DisProt data in mult... |
| harmonizome.downloads | Harmonizome Downloads | download | Product | mixed | was derived from | Harmonizome 3.0 processed dataset dow... |
| harmonizome.kg-neo4j | Harmonizome Knowledge Graph Neo4j Database | harmonizome-kg.maayanlab.cloud | Graph | neo4j | was derived from | Neo4j knowledge graph serialization o... |
| biobtree.api | BioBTree REST API | api | Programming Interface | http | had primary source | REST API for searching identifiers an... |
| genecards.web.interface | GeneCards Web Interface | www.genecards.org | Graphical Interface | http | had primary source | Web-based interface for searching and... |
| biobtree.graph.human-subgraph | BioBTree Knowledge Graph - Human Subgraph (KGX) | 20816742 | Graph | kgx | had primary source | Human-scoped, Neo4j-ready subgraph of... |
| spoke-okn.graph | SPOKE-OKN Graph | spoke.ucsf.edu | Graph | ttl | was influenced by | The SPOKE-OKN knowledge graph, an OKN... |
InterPro is a database of protein families, domains and functional sites in which identifiable features found in known proteins can be applied to unknown protein sequences.
InterPro is a comprehensive database hosted at the European Bioinformatics Institute (EMBL-EBI) that provides functional analysis of proteins by classifying them into families and predicting the presence of domains and important sites. It integrates predictive protein signatures from multiple partner databases into a unified resource.
InterPro integrates signatures from several member databases, including:
InterPro provides:
The primary tool for using InterPro signatures is InterProScan, which allows users to scan their protein sequences against all InterPro’s signatures simultaneously. InterPro data can be accessed via:
InterPro is widely used in genome annotation projects, comparative genomics studies, structural biology research, and functional characterization of proteins across all taxonomic groups.
Created: March 09, 2025 | Last modified: September 23, 2026