is a Data Source.
InterPro is a database of protein families, domains and functional sites in which identifiable features found in known proteins can be applied to unknown protein sequences.
biological systems, proteomics, genomics, drug discovery
infores:interpro
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| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| interpro.web | InterPro Web Interface | interpro | GraphicalInterface | http | Web interface for browsing and search... |
| interpro.api | InterPro API | api | ProgrammingInterface | ❔ | RESTful API for programmatic access t... |
| interpro.interproscan | InterProScan | interproscan-5.74-105.0-64-bit.tar.gz (6.7 GB) | ProcessProduct | java | Software package for scanning protein... |
| interpro.entry_list | InterPro Entry List | entry.list (2.5 MB) | DataModelProduct | tsv | Complete list of InterPro entries wit... |
| interpro.xml | InterPro XML | interpro.xml.gz (38.6 MB) | DataModelProduct | xml | Complete InterPro database in XML for... |
| interpro.match_complete | InterPro Match Complete | match_complete.xml.gz (83.1 GB) | MappingProduct | xml | Complete set of matches between prote... |
| interpro.uniparc_match | UniParc Match | uniparc_match.tar.gz (308.5 GB) | MappingProduct | xml | InterPro matches for UniParc protein ... |
| interpro.protein2ipr | Protein to InterPro Mappings | protein2ipr.dat.gz (19.5 GB) | MappingProduct | tsv | Mappings of protein sequences to Inte... |
| interpro.parent_child_tree | Parent-Child Tree | ParentChildTreeFile.txt (612.9 KB) | DataModelProduct | tsv | Hierarchical relationships between In... |
| interpro.interpro2go | InterPro to GO Mappings | interpro2go (2.9 MB) | MappingProduct | tsv | Mappings between InterPro entries and... |
| ID | Name | URL | Category | Format | Description |
|---|---|---|---|---|---|
| spoke.graph | SPOKE Graph | ❔ | GraphProduct | ❔ | The SPOKE knowledge graph containing ... |
| bioteque.embeddings | Bioteque Embeddings | embeddings | Product | ❔ | Network embeddings of the Bioteque gr... |
| mechreponet.kg | MechRepoNet Knowledge Graph | publication | ❔ | The MechRepoNet knowledge graph in it... | |
| drugmechdb.graph | DrugMechDB Graph Dataset | zenodo.8139357 | GraphProduct | mixed | Curated mechanistic drug–disease path... |
| obo-db-ingest.interpro.obo | interpro OBO | interpro.obo (1.1 MB) | Product | obo | interpro OBO |
| obo-db-ingest.interpro.owl | interpro OWL | interpro.owl (1.3 MB) | Product | owl | interpro OWL |
| obo-db-ingest.interpro.json | interpro OBO Graph JSON | interpro.json (1.1 MB) | Product | json | interpro OBO Graph JSON |
| goa.mapping-files ⚠ | GO Mapping Files | external2go | MappingProduct | txt | Files containing transitive assignmen... |
| kinace.portal | KinAce Web Portal | kinace.kinametrix.com | GraphicalInterface | http | Interactive web interface for explori... |
| string.protein.links | STRING Protein Links | protein.links.v12.0.txt.gz (128.7 GB) | GraphProduct | txt | protein network data (full network, s... |
| string.protein.links.detailed | STRING Protein Links Detailed | protein.links.detailed.v12.0.txt.gz (189.6 GB) | GraphProduct | txt | protein network data (full network, i... |
| string.protein.links.full | STRING Protein Links Full | protein.links.full.v12.0.txt.gz (199.6 GB) | GraphProduct | txt | protein network data (full network, i... |
| string.protein.physical.links | STRING Protein Physical Links | protein.physical.links.v12.0.txt.gz (11.1 GB) | GraphProduct | txt | protein network data (physical subnet... |
| string.protein.physical.links.detailed | STRING Protein Physical Links Detailed | protein.physical.links.detailed.v12.0.txt.gz (13.8 GB) | GraphProduct | txt | protein network data (physical subnet... |
| string.protein.physical.links.full | STRING Protein Physical Links Full | protein.physical.links.full.v12.0.txt.gz (14.5 GB) | GraphProduct | txt | protein network data (physical subnet... |
| string.cog.links | STRING COG Links | COG.links.v12.0.txt.gz (176.8 MB) | GraphProduct | txt | association scores between orthologou... |
| string.cog.links.detailed | STRING COG Links Detailed | COG.links.detailed.v12.0.txt.gz (238.7 MB) | GraphProduct | txt | association scores (incl. subscores p... |
| string.database | STRING Database Network Schema | network_schema.v12.0.sql.gz (262.2 GB) | GraphProduct | ❔ | full database, part II: the networks ... |
| obo-db-ingest.interpro.tsv | interpro Nodes TSV | interpro.tsv (681.5 KB) | Product | tsv | interpro Nodes TSV |
InterPro is a database of protein families, domains and functional sites in which identifiable features found in known proteins can be applied to unknown protein sequences.
InterPro is a comprehensive database hosted at the European Bioinformatics Institute (EMBL-EBI) that provides functional analysis of proteins by classifying them into families and predicting the presence of domains and important sites. It integrates predictive protein signatures from multiple partner databases into a unified resource.
InterPro integrates signatures from several member databases, including:
InterPro provides:
The primary tool for using InterPro signatures is InterProScan, which allows users to scan their protein sequences against all InterPro’s signatures simultaneously. InterPro data can be accessed via:
InterPro is widely used in genome annotation projects, comparative genomics studies, structural biology research, and functional characterization of proteins across all taxonomic groups.
Created: March 09, 2025 | Last modified: February 18, 2026