Evaluation for spoke

Evaluator: Not specified

Evaluated on: 2025-08-23

This is a manual evaluation intended to identify potential barriers to reuse.


Access Level and Types

QuestionAnswerComment
Access to data outside of the knowledge graphYNeighborhood explorer; limited to 10k nodes; API https://spoke.rbvi.ucsf.edu/swagger/
API or online access to the knowledge graphYNeighborhood explorer; limited to 10k nodes
Multiple access options availableY
Source code availabilityN
Downloadable knowledge graphN

Section Score: 3/5

Provenance of Nodes and Edges

QuestionAnswerComment
Source list providedYIn supplemental and on website
Source versions informationYPulled each week
Import dependenciesN
Node and edge sourcesYHttps://spoke.rbvi.ucsf.edu/docs/index.html
Edges deduplicationYSort of; genes and protiens are considered different
Triples source detailsYSome for instance specifies PPI for humans comes from STRING; human disease ontology provides disease associated gene
Edge type schemaY

Section Score: 6/7

Documented standards, schema, construction

QuestionAnswerComment
Biological usable dataYNo custom data transforms that are KG specific
Resolvable IDsYUses Ensembl
Construction documentationYEdge and node types specified with source
Transformation documentationYData is downloaded and integrated as is
Schema usedYUses Biolink when practical

Section Score: 5/5

Update frequency and versioning

QuestionAnswerComment
Stable versionsN
Public tracker informationN
Knowledge graph contact informationYEmail provided
Updated annuallyYUpdated weekly according to paper
Prior versions accessN

Section Score: 2/5

Evaluation - Metrics and Fitness for Purpose

QuestionAnswerComment
Use case providedN
Evaluation against other modelsN
Defined scopeYBiomedical applications such as drug reuposing, disease prediction, embedding EHR data
Multiple evaluation methodsN
Accuracy metricsN

Section Score: 1/5

License Information

QuestionAnswerComment
LicenseCC BY 4.0